anti-Human BMP6 antibody for Enzyme Immunoassay

Recommended BMP6 Antibody (supplied by: Log in to see )

Antigen
Bone Morphogenetic Protein 6 (BMP6) Antibodies
  • BMP6
  • zgc:113595
  • vgr
  • vgr-1
  • vgr1
  • VGR
  • VGR1
  • D13Wsu115e
  • Vgr1
  • bone morphogenetic protein 6
  • bone morphogenetic protein 6 S homeolog
  • BMP6
  • bmp6
  • bmp6.S
  • Bmp6
Epitope
N-Term
13
8
7
6
5
5
4
4
3
2
2
2
1
1
1
1
1
1
1
1
1
Reactivity
Human
106
30
21
3
2
2
2
2
2
2
2
1
Host
Rabbit
95
25
Clonality
Polyclonal
Conjugate
This BMP6 antibody is un-conjugated
14
10
6
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
103
66
49
15
9
6
4
2
2
2
1
1
1
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Catalog No. ABIN357184
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN5551453 EIA IHC (p) Rabbit AA 40-55 Log in to see Polyclonal 0

General

Antigen Bone Morphogenetic Protein 6 (BMP6) Antibodies
Epitope N-Term
(13), (8), (7), (6), (5), (5), (4), (4), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(106), (30), (21), (3), (2), (2), (2), (2), (2), (2), (2), (1)
Host Rabbit
(95), (25)
Clonality
Polyclonal
Conjugate This BMP6 antibody is un-conjugated
(14), (10), (6), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Western Blotting (WB)
(103), (66), (49), (15), (9), (6), (4), (2), (2), (2), (1), (1), (1)
Pubmed 3 references available
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Product Details anti-BMP6 Antibody

Target Details BMP6 Application Details Handling References for anti-BMP6 antibody (ABIN357184) Images
Specificity This antibody detects Bmp6 at N-term.
Purification Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
Immunogen KLH conjugated synthetic peptide selected from the N-terminal region of human Bmp6
Isotype Ig Fraction
Plasmids, Primers & others

Target Details BMP6

Product Details anti-BMP6 Antibody Application Details Handling References for anti-BMP6 antibody (ABIN357184) Images back to top
Antigen
Alternative Name BMP6 (BMP6 Antibody Abstract)
Background The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, Bmp6 has a proposed role in early development. In addition, the fact that BMP6 is closely related to BMP5 and BMP7 has lead to speculation of possible bone inductive activity.Synonyms: BMP-6, Bone morphogenetic protein 6, VGR, VGR1
Molecular Weight 57225 Da
Gene ID 654, 5874
UniProt P22004
Pathways Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process

Application Details

Product Details anti-BMP6 Antibody Target Details BMP6 Handling References for anti-BMP6 antibody (ABIN357184) Images back to top
Application Notes ELISA1: 1,000. Western blot 1: 100 - 1: 500. Immunohistochemistry 1: 10 - 1: 50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-BMP6 Antibody Target Details BMP6 Application Details References for anti-BMP6 antibody (ABIN357184) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

References for anti-BMP6 antibody (ABIN357184)

Product Details anti-BMP6 Antibody Target Details BMP6 Application Details Handling Images back to top
Background publications

Lories, Derese, Ceuppens, Luyten: "Bone morphogenetic proteins 2 and 6, expressed in arthritic synovium, are regulated by proinflammatory cytokines and differentially modulate fibroblast-like synoviocyte apoptosis." in: Arthritis and rheumatism, Vol. 48, Issue 10, pp. 2807-18, 2003

Bobacz, Gruber, Soleiman, Erlacher, Smolen, Graninger: "Expression of bone morphogenetic protein 6 in healthy and osteoarthritic human articular chondrocytes and stimulation of matrix synthesis in vitro." in: Arthritis and rheumatism, Vol. 48, Issue 9, pp. 2501-8, 2003

Tamada, Kitazawa, Gohji, Kamidono, Maeda, Kitazawa: "Molecular cloning and analysis of the 5'-flanking region of the human bone morphogenetic protein-6 (BMP-6)." in: Biochimica et biophysica acta, Vol. 1395, Issue 3, pp. 247-51, 1998

Images

Product Details anti-BMP6 Antibody Target Details BMP6 Application Details Handling References for anti-BMP6 antibody (ABIN357184) back to top
Supplier Images
 image for anti-Bone Morphogenetic Protein 6 (BMP6) (N-Term) antibody (ABIN357184) anti-Bone Morphogenetic Protein 6 (BMP6) (N-Term) antibody
 image for anti-Bone Morphogenetic Protein 6 (BMP6) (N-Term) antibody (ABIN357184) anti-Bone Morphogenetic Protein 6 (BMP6) (N-Term) antibody (Image 2)