anti-Macaque Lysine (K)-Specific Demethylase 1A antibody for Western Blotting

Recommended Lysine (K)-Specific Demethylase 1A Antibody (supplied by: Log in to see )

Antigen
Lysine (K)-Specific Demethylase 1A (KDM1A) Antibodies
  • AOF2
  • BHC110
  • KDM1
  • LSD1
  • 1810043O07Rik
  • AA408884
  • Aof2
  • D4Ertd478e
  • Kdm1
  • Lsd1
  • mKIAA0601
  • DKFZp459N2450
  • RGD1562975
  • aof2
  • kdm1
  • wu:fb82e06
  • wu:fc51a02
  • wu:fj36a05
  • wu:fj66b06
  • KDM1A
  • lsd1
  • xLSD1
  • lysine demethylase 1A
  • lysine (K)-specific demethylase 1A
  • lysine (K)-specific demethylase 1a
  • KDM1A
  • Kdm1a
  • kdm1a
Epitope
AA 100-150
19
9
9
9
7
7
6
6
5
4
4
4
4
3
3
2
2
2
2
2
2
1
Reactivity
Dog (Canine), Human, Macaque, Monkey, Mouse (Murine), Rat (Rattus), Zebrafish (Danio rerio)
204
119
94
22
20
10
9
6
5
4
3
2
1
1
1
Host
Rabbit
153
50
4
Clonality
Polyclonal
Conjugate
Un-conjugated
2
2
2
2
2
2
2
2
2
2
2
2
2
2
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
175
62
61
49
31
26
17
14
9
8
6
6
3
3
1
1
1
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

Submit your validation data for this product and get a full refund. I want to validate this product

Learn more

Available images

Catalog No. ABIN372401
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN290327 IHC (p) WB Rabbit AA 100-150 Log in to see Polyclonal 0
1 ABIN2470089 IHC WB Rabbit AA 100-150 Log in to see Polyclonal 0

General

Antigen Lysine (K)-Specific Demethylase 1A (KDM1A) Antibodies
Epitope AA 100-150
(19), (9), (9), (9), (7), (7), (6), (6), (5), (4), (4), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (1)
Reactivity Dog (Canine), Human, Macaque, Monkey, Mouse (Murine), Rat (Rattus), Zebrafish (Danio rerio)
(204), (119), (94), (22), (20), (10), (9), (6), (5), (4), (3), (2), (1), (1), (1)
Host Rabbit
(153), (50), (4)
Clonality
Polyclonal
Conjugate Un-conjugated
(2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(175), (62), (61), (49), (31), (26), (17), (14), (9), (8), (6), (6), (3), (3), (1), (1), (1), (1)
Supplier Log in to see

Product details

Target Details Application Details Handling Images
Specificity This antibody recognizes Amine Oxidase (Flavin Containing) Domain 2 (AOF2/KDM1A).
Cross-Reactivity (Details) Species reactivity (expected):Dog (Canine), Macaque, Monkey, Mouse, Rat and Zebrafish.
Species reactivity (tested):Human.
Purification Immunoaffinity Chromatography.
Immunogen Synthetic peptide corresponding to a portion of amino acids of human AOF2.
Isotype IgG

Target Details

Product details Application Details Handling Images back to top
Antigen
Alternative Name AOF2 (KDM1A Antibody Abstract)
Background LSD1 is a histone demethylase that specifically demethylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. LSD1 contains a SWIRM domain, a FAD-binding motif, and an amine oxidase domain. This protein is a component of several histone deacetylase complexes, though it silences genes by functioning as a histone demethylase. It acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. LSD1 demethylates both mono- and tri-methylted 'Lys-4' of histone H3. This protein may play a role in the repression of neuronal genes. Alone, it is unable to demethylate H3 'Lys-4' on nucleosomes and requires the presence of RCOR1/CoREST to achieve such activity. It may also demethylate 'Lys-9' of histone H3, a specific tag for epigenetic transcriptional repression, thereby leading to derepression of androgen receptor target genes.Synonyms: BRAF35-HDAC complex protein BHC110, Flavin-containing amine oxidase domain-containing protein 2, KIAA0601, LSD1, Lysine-specific histone demethylase 1
Molecular Weight 93 kDa.
Gene ID 23028
NCBI Accession NP_001009999
UniProt O60341
Pathways Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Negative Regulation of intrinsic apoptotic Signaling

Application Details

Product details Target Details Handling Images back to top
Application Notes Immunohistochemistry on Paraffin Sections: 5 μg/mL. Western blot: 0.5-2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product details Target Details Application Details Images back to top
Concentration 0.5 mg/mL
Buffer PBS containing 0.2 % Gelatin as stabilizer and 0.05 % Sodium Azide as preservative.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Images

Product details Target Details Application Details Handling back to top
Supplier Images
 image for anti-Lysine (K)-Specific Demethylase 1A (KDM1A) (AA 100-150) antibody (ABIN372401) anti-Lysine (K)-Specific Demethylase 1A (KDM1A) (AA 100-150) antibody