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SH2D1A Proteins

(SH2 Domain Containing 1A (SH2D1A))
This gene encodes a protein that plays a major role in the bidirectional stimulation of T and B cells. This protein contains an SH2 domain and a short tail. It associates with the signaling lymphocyte-activation molecule, thereby acting as an inhibitor of this transmembrane protein by blocking the recruitment of the SH2-domain-containing signal-transduction molecule SHP-2 to its docking site. This protein can also bind to other related surface molecules that are expressed on activated T, B and NK cells, thereby modifying signal transduction pathways in these cells. Mutations in this gene cause lymphoproliferative syndrome X-linked type 1 or Duncan disease, a rare immunodeficiency characterized by extreme susceptibility to infection with Epstein-Barr virus, with symptoms including severe mononucleosis and malignant lymphoma. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
SH2D1A Protein (AA 1-128) (His tag) SH2D1A Protein (AA 1-128) (His tag) SH2D1A Protein (AA 1-128) (His tag) (ABIN7125076)

SH2D1A Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA

SH2D1A Protein (AA 1-128) (GST tag) SH2D1A Protein (AA 1-128) (GST tag) SH2D1A Protein (AA 1-128) (GST tag) (ABIN1319861)

SH2D1A Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA

SH2D1A Protein (AA 1-126) (His tag) SH2D1A Protein (AA 1-126) (His tag) SH2D1A Protein (AA 1-126) (His tag) (ABIN3132254)

Crystallography grade SH2D1A Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys

SH2D1A Proteins by Grade

Find SH2D1A Proteins with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

SH2D1A Proteins by Origin

Find SH2D1A Proteins for a variety of species such as anti-Human SH2D1A, anti-Mouse SH2D1A, anti-Cow SH2D1A. The species listed below are among those available. Click on a link to go to the corresponding products.

SH2D1A Proteins by Source

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SH2D1A Proteins by Protein Type

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SH2D1A Proteins by Application

Find SH2D1A Proteins validated for a specific application such as ELISA, WB, SDS, AP. Some of the available applications are listed below. Click on a link to go to the corresponding products.

SH2D1A Proteins by Biological Activity

Find SH2D1A Proteins with a specific Biological Activity. The Biological Activity listed below are among those available. Click on a link to go to the corresponding products.

Popular SH2D1A Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7125076
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1319861
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3132254
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7319330
Quantity 50 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7405861
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7317640
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3011636
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2731954
Quantity 20 μg
Datasheet Datasheet
Reactivity Rat
Source Yeast
Validations
Cat. No. ABIN1475343
Quantity 1 mg
Datasheet Datasheet
Reactivity Saguinus oedipus
Source Yeast
Validations
Cat. No. ABIN1645601
Quantity 1 mg
Datasheet Datasheet
Reactivity Rhesus Monkey
Source Yeast
Validations
Cat. No. ABIN1675967
Quantity 1 mg
Datasheet Datasheet
Reactivity Cow
Source Yeast
Validations
Cat. No. ABIN1628702
Quantity 1 mg
Datasheet Datasheet

Aliases for SH2D1A Proteins

SH2 domain containing 1A (SH2D1A) Proteins
SH2 domain containing 1A (Sh2d1a) Proteins
DSHP Proteins
EBVS Proteins
Gm686 Proteins
IMD5 Proteins
LYP Proteins
MTCP1 Proteins
RGD1562408 Proteins
SAP Proteins
SAP/SH2D1A Proteins
SH2D1A Proteins
XLP Proteins
XLPD Proteins
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