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|Antigen||Aminolevulinate, delta-, Synthase 1 (ALAS1) Antibodies|
|Reactivity||Human, Mouse (Murine), Rat (Rattus) Alternatives|
|Conjugate||This ALAS1 antibody is un-conjugated Alternatives|
Western Blotting (WB)
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Product Details anti-ALAS1 AntibodyTarget Details ALAS1 Application Details Handling Images
|Specificity||ALAS1 antibody was raised against the N terminal of ALAS1|
|Immunogen||ALAS1 antibody was raised using the N terminal of ALAS1 corresponding to a region with amino acids ETSAGPSVVSVKTDGGDPSGLLKNFQDIMQKQRPERVSHLLQDNLPKSVS|
|Plasmids, Primers & others|
Target Details ALAS1Product Details anti-ALAS1 Antibody Application Details Handling Images back to top
|Alternative Name||ALAS1 (ALAS1 Antibody Abstract)|
|Background||Delta-aminolevulinate synthase (ALAS, EC 188.8.131.52) catalyzes the condensation of glycine with succinyl-CoA to form delta-aminolevulinic acid. This nuclear-encoded mitochondrial enzyme is the first and rate-limiting enzyme in the mammalian heme biosynthetic pathway. There are 2 tissue-specific isozymes: a housekeeping enzyme encoded by the ALAS1 gene and an erythroid tissue-specific enzyme encoded by ALAS2.|
|Molecular Weight||70 kDa (MW of target protein)|
|Pathways||Regulation of Lipid Metabolism by PPARalpha|
Application DetailsProduct Details anti-ALAS1 Antibody Target Details ALAS1 Handling Images back to top
WB: 1 µg/mL
Optimal conditions should be determined by the investigator.
ALAS1 Blocking Peptide, catalog no. 33R-2769, is also available for use as a blocking control in assays to test for specificity of this ALAS1 antibody
|Restrictions||For Research Use only|
HandlingProduct Details anti-ALAS1 Antibody Target Details ALAS1 Application Details Images back to top
|Reconstitution||Lyophilized powder. Add distilled water for a 1 mg/mL concentration of ALAS1 antibody in PBS|
Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.
|Storage Comment||Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.|
ImagesProduct Details anti-ALAS1 Antibody Target Details ALAS1 Application Details Handling back to top