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anti-Human ATOH8 Antibodies:
anti-Mouse (Murine) ATOH8 Antibodies:
anti-Rat (Rattus) ATOH8 Antibodies:
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Atoh8 is dispensible for zebrafish development under standard laboratory conditions.
ATOH8, GATA4 (show GATA4 Antibodies), and FOG2 (show ZFPM2 Antibodies) associate in a single complex
These findings raise the possibility that ATOH8 is a pivotal regulator in nasopharyngeal carcinoma tumorigenesis
Data demonstrated that ATOH8 expression was upregulated in colorectal cancer (CRC (show CALR Antibodies)) patients, and seems to increase the malignancy potential of CRC (show CALR Antibodies).
calcineurin mediates the subcellular localization of ATOH8, which reveals the regulation of ATOH8 transcriptional activity by calcium signaling via calcineurin.
Regeneration marker ATOH8 contributes to muscle cell differentiation in healthy and diseased human muscle tissue.
ATOH8 appears to be a tumor suppressor that induces stem-cell features and chemoresistance in HCC (show FAM126A Antibodies) cells.
Data show that in ATOH8 was hosted in one chromosome which is a fusion product of two orthologous chromosomes in non-human. primates.
ATOH8 is an important transcriptional regulator of hepcidin (show HAMP Antibodies) in beta-thalassemia.
Atoh8 modulates activation of the endocrine program.
It has observed Math6 expression in various organs at early and late stages of mouse development, which illustrates the involvement of Math6 in multiple developmental events.
results reveal distinctive transcriptional properties of Atoh8 within the atonal-related bHLH family that may be associated with the acquisition of new biological functions.
Neurogenin3 (show NEUROG3 Antibodies) can trigger the conversion of Math6 from a poorly transcribed bivalent to an active monovalent state in vitro, hence providing a mechanism whereby Neurogenin3 (show NEUROG3 Antibodies) may activate Math6 in endocrine progenitors
Math6 may participate in kidney development and may be a permissive factor for podocyte differentiation.
Bmp6 (show BMP6 Antibodies), Smad7 (show SMAD7 Antibodies), Id1 (show ID1 Antibodies), and Atoh8 transcripts are significantly modulated by the dietary iron content; activation of Smad7 (show SMAD7 Antibodies), Id1 (show ID1 Antibodies), and Atoh8 transcription by iron requires Smad4 (show SMAD4 Antibodies).
results demonstrate that Math6 is indispensable for early embryonic development and indicate a more widespread function for this factor in tissue-specific differentiation processes that are dependent on class II bHLH genes
Putative transcription factor. May be implicated in specification and differentiation of neuronal cell lineages in the brain. May participate in kidney development and may be involved in podocyte differentiation (By similarity).
protein atonal homolog 8
, atonal homolog 8 (Drosophila)
, atonal homolog 8
, atonal homolog 6
, basic helix loop helix transcription factor 6
, basic helix-loop-helix transcription factor 6
, class A basic helix-loop-helix protein 21
, helix-loop-helix protein hATH-6
, helix-loop-helix protein mATH-6