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Data indicate that duplicate col14a1 genes col14a1a (id 321298; XM_001922011 on chromosome 16) and col14a1b (id 100331704; XM_003200499 on chromosome 19) are differentially expressed during embryogenesis.
the intima+media of IPAH vessels, collagens (COL4A5 (show COL4a5 Proteins), COL14A1, and COL18A1 (show COL18A1 Proteins)), matrix metalloproteinase (MMP) 19 (show MMP19 Proteins), and a disintegrin and metalloprotease (ADAM) 33 (show ADAM33 Proteins) were higher expressed, whereas MMP10 (show MMP10 Proteins), ADAM17 (show ADAM17 Proteins), TIMP1 (show TIMP1 Proteins), and TIMP3 (show TIMP3 Proteins) were less abundant.
COL14A1 would be a casual gene for punctate palmoplantar keratoderma.
In addition to binding collagen I, COMP (show COMP Proteins) binds to collagens XII and XIV via their C-terminal collagenous domains.
the fibronectin (show FN1 Proteins) type III domain of collagen XIV is an inducer of quiescence and differentiation in fibroblasts and preadipocytes
The aim of this study was therefore to test the association between polymorphisms within COL12A1 and COL14A1 and Achilles tendon injuries
Col14a1 deficiency leads to a greater increase in left ventricular wall thickening in response to pathological pressure overload compared to wild type animals.
This gene encodes the alpha chain of type XIV collagen, a member of the FACIT (fibril-associated collagens with interrupted triple helices) collagen family. Type XIV collagen interacts with the fibril surface and is involved in the regulation of fibrillogenesis.
collagen alpha-1(XIV) chain
, collagen, type XIV, alpha 1 (undulin)
, procollagen, type XIV, alpha 1
, collagen, type XIV, alpha 1
, type XIV collagen alpha 1 chain
, collagen alpha-1(XIV) chain-like
, undulin (fibronectin-tenascin-related)
, alpha1 (XIV) collagen
, collagen XIV
, collagen type XIV
, collagen type XIV/undulin