anti-Human Arginine Vasopressin Receptor 1B antibody for Flow Cytometry

Recommended Arginine Vasopressin Receptor 1B Antibody (supplied by: Log in to see )

Antigen
Arginine Vasopressin Receptor 1B (AVPR1B) Antibodies
  • LOC443050
  • AVPR1B
  • si:ch211-125a15.3
  • AVPR3
  • V3/V1b
  • VIBR
  • VPR3
  • arginine vasopressin receptor 1B
  • arginine vasopressin receptor 1Ab
  • AVPR1B
  • avpr1ab
  • Avpr1b
Reactivity
Human, Mouse (Murine), Rat (Rattus)
98
55
50
6
4
4
3
2
2
2
1
1
Host
Rabbit
112
40
Clonality
Polyclonal
Conjugate
PE
10
10
10
6
6
6
1
1
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS)
112
85
37
31
13
6
4
2
2
1
1
1
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Catalog No. ABIN1428255
$ 427.90
Plus shipping costs $45.00

General

Antigen Arginine Vasopressin Receptor 1B (AVPR1B) Antibodies
Reactivity Human, Mouse (Murine), Rat (Rattus)
(98), (55), (50), (6), (4), (4), (3), (2), (2), (2), (1), (1)
Host Rabbit
(112), (40)
Clonality
Polyclonal
Conjugate PE
(10), (10), (10), (6), (6), (6), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Flow Cytometry (FACS)
(112), (85), (37), (31), (13), (6), (4), (2), (2), (1), (1), (1)
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Product details

Target Details Application Details Handling Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human AVP Receptor V3
Isotype IgG

Target Details

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Antigen
Alternative Name Avpr1b/Avp Receptor V3 (AVPR1B Antibody Abstract)
Background

Vasopressin (AVP), the antidiuretic hormone, is a cyclic nonpeptide that is involved in the regulation of body fluid osmolality (1-3). AVP mediates its effects through a family of G-protein coupled receptors, the vasopressin receptors type V1a, V2 and V3 (also designated V1b) (1,2). The AVP receptor V1a is responsible for several functions, including blood vessel constriction, liver glycogenolysis and platelet adhesion (3). It is detected as a full length protein and a shorter protein, which results from proteolytic cleavage of its amino terminus (4). The V1a receptor is coupled to Gq/11 protein, which increases the intracellular calcium concentration (3). The human AVP receptor V2 gene maps to chromosome Xq28 and is expressed in lung and kidney (5,6). Mutations in the V2 receptor result in nephrogenic diabetes insipidus (NDI), a rare X-linked disorder characterized by the inability of the kidney to concentrate urine in response to AVP (5,7). The AVP Receptor V2 activates the Gs protein and the cyclic AMP second messenger system (7). The AVP receptor V3 is preferentially expressed in the pituitary and stimulates the release of adrenocorticotropic hormone (ACTH) in response to AVP by mobilizing intracellular calcium stores (8). AVP receptor antagonists may have potential therapeutic effects in hypertension, congestive heart failure, nephrotic syndrome and ACTH-secreting tumors (2).

Subcellular location: Extracellular


Synonyms: Antidiuretic hormone receptor 1b, Arginine vasopressin receptor 1B, Arginine vasopressin receptor 3, AVPR V1b, AVPR V3, Avpr1b, AVPR3, Pituitary vasopressin receptor 3, V1bR, V1BR_HUMAN, Vasopressin V1b receptor, Vasopressin V3 receptor, VPR3.
Pathways Regulation of Systemic Arterial Blood Pressure by Hormones

Application Details

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Application Notes FCM(1:20-100)
Comment

Exitation/Emission: 480,565nm/578nm

Restrictions For Research Use only

Handling

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Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at 4°C
Expiry Date 12 months