anti-Human Exportin 5 antibody for Enzyme Immunoassay

Recommended Exportin 5 Antibody (supplied by: Log in to see )

Antigen
Exportin 5 (XPO5) Antibodies
  • exp5
  • CG12234
  • Dmel\\CG12234
  • Exp-5
  • Exp5
  • RanBP21
  • dmExp5
  • 2410004H11Rik
  • 2700038C24Rik
  • AI648907
  • AW549301
  • RanBp21
  • mKIAA1291
  • exportin-5
  • ranbp21
  • DDBDRAFT_0185980
  • DDBDRAFT_0237583
  • DDB_0185980
  • DDB_0237583
  • XPO5
  • exportin 5
  • CG12234 gene product from transcript CG12234-RB
  • armadillo-like helical domain-containing protein
  • XPO5
  • Ranbp21
  • Xpo5
  • xpo5
Epitope
C-Term, AA 1122-1152
10
9
7
6
5
3
3
2
2
2
2
1
1
1
Reactivity
Human
64
35
33
5
5
4
3
3
1
1
1
Host
Rabbit
58
7
Clonality
Polyclonal
Conjugate
Un-conjugated
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
53
18
13
12
12
7
6
4
4
1
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Catalog No. ABIN955603
$ 390.50
Plus shipping costs $45.00

General

Antigen Exportin 5 (XPO5) Antibodies
Epitope C-Term, AA 1122-1152
(10), (9), (7), (6), (5), (3), (3), (2), (2), (2), (2), (1), (1), (1)
Reactivity Human
(64), (35), (33), (5), (5), (4), (3), (3), (1), (1), (1)
Host Rabbit
(58), (7)
Clonality
Polyclonal
Conjugate Un-conjugated
(3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Western Blotting (WB)
(53), (18), (13), (12), (12), (7), (6), (4), (4), (1)
Pubmed 4 references available
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Product details

Target Details Application Details Handling References Images
Specificity This antibody detects Human XPO5 / Exportin-5 (C-term).
Purification Protein A column, followed by peptide affinity purification
Immunogen KLH conjugated synthetic peptide between 1122-1152 amino acids from the C-terminal region of Human Exportin-5. Genename: XPO5
Isotype Ig Fraction

Target Details

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Antigen
Alternative Name XPO5 / Exportin-5 (XPO5 Antibody Abstract)
Background Exportin-5 belongs to a large family of karyopherins (see MIM 602738) that mediate the transport of proteins and other cargo between the nuclear and cytoplasmic compartments.Synonyms: KIAA1291, RANBP21, Ran-binding protein 21
Molecular Weight 136311 Da
Gene ID 57510
NCBI Accession NP_065801
Pathways Regulatory RNA Pathways, Protein targeting to Nucleus

Application Details

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Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

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Format Liquid
Concentration 0.25 mg/mL
Buffer PBS, 0.09 % (W/V) Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References

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Background publications

Melo, Moutinho, Ropero, Calin, Rossi, Spizzo, Fernandez, Davalos, Villanueva, Montoya, Yamamoto, Schwartz, Esteller: "A genetic defect in exportin-5 traps precursor microRNAs in the nucleus of cancer cells." in: Cancer cell, Vol. 18, Issue 4, pp. 303-15, 2010

Kim, Choi, Jin, Kang, Choi, Jeon, Lee, Kim, Kim, Kim, Son, Jung, Park: "Association of a common AGO1 variant with lung cancer risk: a two-stage case-control study." in: Molecular carcinogenesis, Vol. 49, Issue 10, pp. 913-21, 2010

Wilker, Baccarelli, Suh, Vokonas, Wright, Schwartz: "Black carbon exposures, blood pressure, and interactions with single nucleotide polymorphisms in MicroRNA processing genes." in: Environmental health perspectives, Vol. 118, Issue 7, pp. 943-8, 2010

Hanna, Kruskal, Ezekowitz, Bloom, Collier: "Role of macrophage oxidative burst in the action of anthrax lethal toxin." in: Molecular medicine (Cambridge, Mass.), Vol. 1, Issue 1, pp. 7-18, 1996

Images

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Supplier Images
Western Blotting (WB) image for anti-Exportin 5 (XPO5) (AA 1122-1152), (C-Term) antibody (ABIN955603) Western blot analysis of XPO5 Antibody (C-term) Cat.-No AP54589PU-N in human placenta...