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Human HPR Protein expressed in Escherichia coli (E. coli) - ABIN1099135
Inamoto, Martin, Paczesny, Tabellini, Momin, Mumaw, Flowers, Lee, Carpenter, Storer, Hanash, Hansen: Association of Plasma CD163 Concentration with De Novo-Onset Chronic Graft-versus-Host Disease. in Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2017
This gene encodes a haptoglobin-related protein that binds hemoglobin as efficiently as haptoglobin. Unlike haptoglobin, plasma concentration of this protein is unaffected in patients with sickle cell anemia and extensive intravascular hemolysis, suggesting a difference in binding between haptoglobin-hemoglobin and haptoglobin-related protein-hemoglobin complexes to CD163, the hemoglobin scavenger receptor. This protein may also be a clinically important predictor of recurrence of breast cancer.
, Haptoglobin-related locus