anti-Rat (Rattus) Chloride Channel, Nucleotide-Sensitive, 1A antibody for Immunofluorescence (Paraffin-embedded Sections)

Recommended Chloride Channel, Nucleotide-Sensitive, 1A Antibody (supplied by: Log in to see )

Antigen
Chloride Channel, Nucleotide-Sensitive, 1A (CLNS1A) Antibodies
  • clci
  • clns1b
  • icln
  • CLCI
  • CLNS1B
  • ICln
  • 2610036D06Rik
  • 2610100O04Rik
  • Clci
  • Clcni
  • ICLN
  • Icln
  • pICln
  • pIcIn
  • chloride channel, nucleotide-sensitive, 1A
  • regulatory protein
  • CLNS1A
  • clns1a
  • Clns1a
Reactivity
Human, Mouse (Murine), Rat (Rattus)
52
23
20
7
5
2
2
2
1
1
1
1
1
1
Host
Rabbit
47
7
Clonality
Polyclonal
Conjugate
Alexa Fluor 594
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
39
13
12
8
8
6
5
4
3
3
3
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Catalog No. ABIN2811749
$ 405.90
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN1422900 IF (p) Cy5 Rabbit IgG Log in to see Polyclonal
1 ABIN1422899 IF (p) Cy3 Rabbit IgG Log in to see Polyclonal
1 ABIN1422901 IF (p) Cy5.5 Rabbit IgG Log in to see Polyclonal
1 ABIN1422902 IF (p) Cy7 Rabbit IgG Log in to see Polyclonal
1 ABIN1405029 IF (p) Alexa Fluor 350 Rabbit IgG Log in to see Polyclonal
1 ABIN1405031 IF (p) Alexa Fluor 555 Rabbit IgG Log in to see Polyclonal
1 ABIN1405030 IF (p) Alexa Fluor 488 Rabbit IgG Log in to see Polyclonal
1 ABIN1405032 IF (p) Alexa Fluor 647 Rabbit IgG Log in to see Polyclonal
1 ABIN1405034 IF (p) FITC Rabbit IgG Log in to see Polyclonal
1 ABIN1385503 IF (p) IHC (p) WB Rabbit IgG Log in to see Polyclonal
1 ABIN5000220 IF (p) Alexa Fluor 750 Rabbit IgG Log in to see Polyclonal
1 ABIN5000219 IF (p) Alexa Fluor 680 Rabbit IgG Log in to see Polyclonal

General

Antigen Chloride Channel, Nucleotide-Sensitive, 1A (CLNS1A) Antibodies
Reactivity Human, Mouse (Murine), Rat (Rattus)
(52), (23), (20), (7), (5), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Host Rabbit
(47), (7)
Clonality
Polyclonal
Conjugate Alexa Fluor 594
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p))
(39), (13), (12), (8), (8), (6), (5), (4), (3), (3), (3)
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Product details

Target details Application Details Handling Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human CLNS1A/pICln
Isotype IgG

Target details

Product details Application Details Handling Images back to top
Antigen
Alternative Name CLNS1A (CLNS1A Antibody Abstract)
Background

The formation of the spliceosome includes the assembly of Sm proteins in an ordered manner onto snRNAs. This process is mediated by the survival of motor neuron (SMN) protein, and is enhanced by modification of specific arginine residues in the Sm proteins to symmetrical dimethylarginines (sDMAs). sDMA modification of Sm proteins is catalyzed by the methylosome, a complex comprised of the type II methyltransferase PRMT5 (also designated Jak-binding protein 1, JBP1), pICln, and two novel factors. PRMT5 binds the Sm proteins via their arginine- and glycine-rich (RG) domains, while pICln binds the Sm domains. pICln also acts as an inhibitor of SnRNP assembly by preventing specific interactions between Sm proteins required for the formation of the Sm core. pICln is a highly conserved, ubiquitously expressed protein that localizes primarily to the cytoplasm, and may play a role as a swelling-activated anion channel or a channel regulator in addition to its function in the methylosome. The gene encoding human pICln maps to chromosome 11q14.1.

Synonyms: nucleotide sensitive 1A, Chloride channel, Chloride channel nucleotide sensitive 1A, Chloride channel regulatory protein, Chloride conductance regulatory protein ICln, Chloride ion current inducer protein, ClCI, CLNS 1A, Clns1a, CLNS1B, ICln, ICln, ICLN_HUMAN, Methylosome subunit pICln, Reticulocyte pICln

Gene ID 1207
Pathways Ribonucleoprotein Complex Subunit Organization

Application Details

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Application Notes IF(IHC-P) 1:50-200
Restrictions For Research Use only

Handling

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Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store at 4°C
Expiry Date 12 months