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Gemin6 is a component of the SMN (show STMN1 ELISA Kits) complex that localizes to gems and interacts with several Sm proteins of the spliceosomal snRNPs.
Gemin8 (show GEMIN8 ELISA Kits) has an essential role in the proper structural organization of the SMN (show STMN1 ELISA Kits) complex and the involvement of the heteromeric subunit containing Gemin6, Gemin7 (show GEMIN7 ELISA Kits), Gemin8 (show GEMIN8 ELISA Kits), and Unrip (show STRAP ELISA Kits) in the recruitment of Sm proteins to the snRNP (show LSM2 ELISA Kits) assembly pathway
GEMIN6 is part of a large macromolecular complex, localized to both the cytoplasm and the nucleus, that plays a role in the cytoplasmic assembly of small nuclear ribonucleoproteins (snRNPs). Other members of this complex include SMN (MIM 600354), GEMIN2 (SIP1\; MIM 602595), GEMIN3 (DDX20\; MIM 606168), GEMIN4 (MIM 606969), and GEMIN5 (MIM 607005).
, gem-associated protein 6
, gemin 6