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Cow (Bovine) Polyclonal MAT2A Primary Antibody for ICC, IF - ABIN410043
Ramani, Tomasi: Transcriptional regulation of methionine adenosyltransferase 2A by peroxisome proliferator-activated receptors in rat hepatic stellate cells. in Hepatology (Baltimore, Md.) 2012
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Polyclonal MAT2A Primary Antibody for WB - ABIN540677
Rodríguez, Boukaba, Sandoval, Georgieva, Latasa, García-Trevijano, Serviddio, Nakamura, Avila, Sastre, Torres, Mato, López-Rodas: Transcription of the MAT2A gene, coding for methionine adenosyltransferase, is up-regulated by E2F and Sp1 at a chromatin level during proliferation of liver cells. in The international journal of biochemistry & cell biology 2007
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Human Monoclonal MAT2A Primary Antibody for IHC (p), IHC - ABIN449884
Rho, Lampe: High-throughput screening for native autoantigen-autoantibody complexes using antibody microarrays. in Journal of proteome research 2013
Show all 2 Pubmed References
Cow (Bovine) Polyclonal MAT2A Primary Antibody for WB - ABIN410047
Ramani, Donoyan, Tomasi, Park: Role of methionine adenosyltransferase α2 and β phosphorylation and stabilization in human hepatic stellate cell trans-differentiation. in Journal of cellular physiology 2015
MAT2A expression is upregulated through mRNA stabilization upon SAM (show TTN Antibodies) depletion.
Increased MAT2A expression is associated with recurrence in hepatocellular carcinoma.
High MAT2A expression is associated with tamoxifen-resistant breast cancer.
METTL16 (show METTL16 Antibodies) that controls MAT2A intron retention in response to intracellular SAM (show TTN Antibodies) levels; splicing of the MAT2A retained intron is rapidly induced upon Met depletion, and this effect requires a conserved hairpin which is a METTL16 (show METTL16 Antibodies) m6A (show GPM6A Antibodies) substrate.
S-adenosyl-L-methionine (show AS3MT Antibodies) diminishes hepatitis C virus expression by altering MAT1A (show MAT1A Antibodies)/2A signaling in hepatocytes.
methionine adenosyltransferase II alpha (MAT2A), and the arginine methyltransferase, PRMT5 (show PRMT5 Antibodies), as vulnerable enzymes in cells with MTAP (show MTAP Antibodies) deletion.
acet (show EP300 Antibodies)ylation decreased in hepatocellular cancer
The data presented here support the conclusion that rare genetic variants in MAT2A predispose individuals to thoracic aortic disease.
Results suggest that MAT2A is downregulated in cancer tissues of renal cell carcinomas patients and has function of tumor suppressor though repressing the expression of heme oxygenase-1 (show HMOX1 Antibodies).
Liver-specific isoenzyme MAT1A (show MAT1A Antibodies) is genetically linked with an inborn metabolic disorder of hypermethioninemia, as well as a ubiquitously expressed isoenzyme MAT2A, whose enzymatic activity is regulated by an associated subunit MAT2B (show MAT2B Antibodies).
SIRT1 (show SIRT1 Antibodies) knock-out embryos display reduced Mat2a expression and histone methylation and are sensitive to maternal methionine restriction-induced lethality, whereas maternal methionine supplementation increases the survival of SIRT1 (show SIRT1 Antibodies) knock-out newborn mice.
P300 (show NOTCH1 Antibodies) acetylates MAT IIalpha at lysine residue 81 and destabilizes MAT IIalpha by promoting its ubiquitylation and subsequent proteasomal degradation.
MATIIalpha represses the expression of cyclooxygenase 2 (COX-2 (show PTGS2 Antibodies)), encoded by Ptgs2 (show PTGS2 Antibodies), by specifically interacting with histone H3K9 methyltransferase SETDB1 (show SETDB1 Antibodies).
Methionine adenosyltransferase II serves as a transcriptional corepressor of Maf (show MAF Antibodies) oncoprotein
MAT2A and MAT2beta (show MAT2B Antibodies) genes are induced during hepatic stellate cell activation
up-regulation of MAT2A also provides a growth advantage and s-adenosylmethionine and methylthioadenosine can block mitogenic signaling in colon cancer cells.
The protein encoded by this gene catalyzes the production of S-adenosylmethionine (AdoMet) from methionine and ATP. AdoMet is the key methyl donor in cellular processes.
methionine adenosyltransferase II, alpha
, S-adenosylmethionine synthetase isoform type-2-like
, MAT 2
, S-adenosylmethionine synthase isoform type-2
, adoMet synthase 2
, adoMet synthetase 2
, methionine adenosyltransferase 2
, S-adenosylmethionine synthetase isoform type-2
, non-hepatic-type S-adenosylmethionine synthetase