anti-Human Angiopoietin 2 antibody for ELISA

Recommended Angiopoietin 2 Antibody

Antigen
Angiopoietin 2 (ANGPT2) Antibodies
  • AGPT2
  • ANG2
  • Agpt2
  • Ang-2
  • Ang2
  • ang2
  • angpt2
  • ANGIOPOIETIN-2
  • ANG-2
  • ANGPT2
  • angiopoietin 2
  • angiopoietin 2b
  • ANGPT2
  • Angpt2
  • angpt2b
Reactivity
Human
123
82
59
21
5
4
3
3
2
1
1
1
1
Host
Human
140
15
5
2
1
1
Antibody Type
Recombinant Antibody
Clonality
Monoclonal
Conjugate
This Angiopoietin 2 antibody is un-conjugated
15
7
6
4
4
4
4
4
4
1
1
1
1
1
1
1
1
Application
ELISA, Functional Studies (Func)
105
62
61
21
18
15
13
10
7
7
6
2
2
Options
Catalog No. ABIN5564219
$ 557.94
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Clonality References Details
13.656592 ABIN5564221 ELISA Func Human IgG2 Angy-1-4 0
13.656592 ABIN5564220 ELISA Func Human IgG2 Angy-1-4 0
13.656592 ABIN5564223 ELISA Func Mouse IgG2b Angy-2-1 0
13.656592 ABIN5564222 ELISA Func Human IgG2 Angy-1-4 0
13.656592 ABIN5564225 ELISA Func Mouse IgG2b Angy-2-1 0
13.656592 ABIN5564224 ELISA Func Mouse IgG2b Angy-2-1 0
13.656592 ABIN5564226 ELISA Func Mouse IgG2b Angy-2-1 0
11.5 ABIN5518732 ELISA IHC (p) WB Rabbit IgG AA 180-283 Polyclonal 3
10 ABIN6259928 ELISA IHC WB Rabbit IgG Polyclonal 0
10 ABIN2421171 IHC ELISA WB Rabbit IgG Polyclonal 0
7 ABIN5572508 ELISA IHC WB Rabbit IgG Polyclonal 0
7 ABIN1030235 ELISA WB Rabbit C-Term Polyclonal 0
7 ABIN5572509 ELISA IHC (p) WB Rabbit Polyclonal 0
7 ABIN2427747 IHC ELISA Rabbit IgG Polyclonal 0
4 ABIN1997235 ELISA WB Rabbit IgG AA 1-496 Polyclonal 0
4 ABIN1997237 IP ELISA WB Rabbit IgG AA 1-496 Polyclonal 0
4 ABIN5647041 ELISA IHC (p) WB Rabbit IgG Polyclonal 0
1 ABIN2861356 IHC ELISA WB Rabbit C-Term Polyclonal 0
1 ABIN6656107 ELISA IHC WB Rabbit IgG C-Term Polyclonal 0
1 ABIN2200901 IHC ELISA WB HRP Rabbit IgG C-Term, AA 404-432 Polyclonal 0

General

Antigen Angiopoietin 2 (ANGPT2) Antibodies
Reactivity Human
(123), (82), (59), (21), (5), (4), (3), (3), (2), (1), (1), (1), (1)
Host Human
(140), (15), (5), (2), (1), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This Angiopoietin 2 antibody is un-conjugated
(15), (7), (6), (4), (4), (4), (4), (4), (4), (1), (1), (1), (1), (1), (1), (1), (1)
Application ELISA, Functional Studies (Func)
(105), (62), (61), (21), (18), (15), (13), (10), (7), (7), (6), (2), (2)
Supplier

Product Details anti-Angiopoietin 2 Antibody

Target Details Angiopoietin 2 Application Details Handling Images
Specificity Recognizes human angiopoietin-2.
Cross-Reactivity Human
No Cross-Reactivity Mouse (Murine)
Cross-Reactivity (Details) Does not recognize mouse angiopoietin-2 and human angiopoietin-1.
Purity >95 % (SDS-PAGE)
Immunogen Recombinant human angiopoietin-2.
Clone Angy-1-4
Isotype IgG2
Plasmids, Primers & others

Target Details Angiopoietin 2

Product Details anti-Angiopoietin 2 Antibody Application Details Handling Images back to top
Antigen
Alternative Name Angiopoietin-2 (ANGPT2 Antibody Abstract)
Background Angiopoietin-1 (Ang-1) and Angiopoietin-2 (Ang-2) are closely related secreted ligands which bind with similar affinity to Tie-2. Tie-2 and angiopoietins have been shown to play critical roles in embryogenic angiogenesis and in maintaining the integrity of the adult vasculature. Ang-1 activates Tie-2 signaling on endothelial cells to promote chemotaxis, cell survival, cell sprouting, vessel growth and stabilization. Ang-2 has been identified as a secreted protein ligand of Tie-2 and has alternatively been reported to be an antagonist for Ang-1 induced Tie-2 signaling as well as an agonist for Tie-2 signaling, depending on the cell context. anti-Angiopoietin-2 (human), mAb (rec.) (blocking) (Angy-1-4) is an antibody developed by antibody phage display technology using a human naive antibody gene library. These libraries consist of scFv (single chain fragment variable) composed of VH (variable domain of the human immunoglobulin heavy chain) and VL (variable domain of the human immunoglobulin light chain) connected by a polypeptide linker. The antibody fragments are displayed on the surface of filamentous bacteriophage (M13). This scFv was selected by affinity selection on antigen in a process termed panning. Multiple rounds of panning are performed to enrich for antigen-specific scFv-phage. Monoclonal antibodies are subsequently identified by screening after each round of selection. The selected monoclonal scFv is cloned into an appropriate vector containing a Fc portion of interest and then produced in mammalian cells to generate an IgG like scFv-Fc fusion protein.
UniProt O15123
Pathways RTK Signaling

Application Details

Product Details anti-Angiopoietin 2 Antibody Target Details Angiopoietin 2 Handling Images back to top
Comment

anti-Angiopoietin-2 (human), mAb (rec.) (blocking) (Angy-1-4) is composed of human variable regions (VH and VL) (lambda-chain) of immunoglobulin fused to the human lgG2 Fc domain.

Restrictions For Research Use only

Handling

Product Details anti-Angiopoietin 2 Antibody Target Details Angiopoietin 2 Application Details Images back to top
Format Liquid
Concentration 1 mg/mL
Buffer In PBS containing 10 % glycerol and 0.02 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C.
Expiry Date 12 months