anti-Mouse (Murine) Angiopoietin 2 antibody for Functional Studies

Recommended Angiopoietin 2 Antibody (supplied by: Log in to see )

Antigen
Angiopoietin 2 (ANGPT2) Antibodies
  • ang2
  • angpt2
  • ANG-2
  • ANGPT2
  • Agpt2
  • Ang-2
  • Ang2
  • AGPT2
  • ANG2
  • ANGIOPOIETIN-2
  • angiopoietin 2b
  • angiopoietin-2
  • angiopoietin 2
  • angpt2b
  • ANG-2
  • ANGPT2
  • LOC100225992
  • Angpt2
Reactivity
Human, Mouse (Murine)
111
59
37
20
15
5
3
3
2
2
1
1
1
1
Host
Mouse
108
27
6
2
1
1
Antibody Type
Recombinant Antibody
Clonality
Monoclonal
Conjugate
This Angiopoietin 2 antibody is un-conjugated
10
7
7
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
ELISA, Functional Studies (Func)
103
61
57
31
25
19
17
13
13
10
8
7
2
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Catalog No. ABIN5564223
$ 414.75
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN5564224 ELISA Func Mouse IgG2b Log in to see Angy-2-1
1 ABIN5564225 ELISA Func Mouse IgG2b Log in to see Angy-2-1
1 ABIN5564226 ELISA Func Mouse IgG2b Log in to see Angy-2-1

General

Antigen Angiopoietin 2 (ANGPT2) Antibodies
Reactivity Human, Mouse (Murine)
(111), (59), (37), (20), (15), (5), (3), (3), (2), (2), (1), (1), (1), (1)
Host Mouse
(108), (27), (6), (2), (1), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This Angiopoietin 2 antibody is un-conjugated
(10), (7), (7), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application ELISA, Functional Studies (Func)
(103), (61), (57), (31), (25), (19), (17), (13), (13), (10), (8), (7), (2)
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Product Details anti-Angiopoietin 2 Antibody

Target Details Angiopoietin 2 Application Details Handling Images
Specificity Recognizes human and mouse angiopoietin-2.
Cross-Reactivity Human, Mouse (Murine)
Cross-Reactivity (Details) Does not detect human angiopoietin-1.
Purity >95 % (SDS-PAGE)
Immunogen Recombinant human angiopoietin-2.
Clone Angy-2-1
Isotype IgG2b

Target Details Angiopoietin 2

Product Details anti-Angiopoietin 2 Antibody Application Details Handling Images back to top
Antigen
Alternative Name Angiopoietin-2 (ANGPT2 Antibody Abstract)
Background Angiopoietin-1 (Ang-1) and Angiopoietin-2 (Ang-2) are closely related secreted ligands which bind with similar affinity to Tie-2. Tie-2 and angiopoietins have been shown to play critical roles in embryogenic angiogenesis and in maintaining the integrity of the adult vasculature. Ang-1 activates Tie-2 signaling on endothelial cells to promote chemotaxis, cell survival, cell sprouting, vessel growth and stabilization. Ang-2 has been identified as a secreted protein ligand of Tie-2 and has alternatively been reported to be an antagonist for Ang-1 induced Tie-2 signaling as well as an agonist for Tie-2 signaling, depending on the cell context. anti-Angiopoietin-2, mAb (rec.) (blocking) (Angy-2-1) is an antibody developed by antibody phage display technology using a human naive antibody gene library. These libraries consist of scFv (single chain fragment variable) composed of VH (variable domain of the human immunoglobulin heavy chain) and VL (variable domain of the human immunoglobulin light chain) connected by a polypeptide linker. The antibody fragments are displayed on the surface of filamentous bacteriophage (M13). This scFv was selected by affinity selection on antigen in a process termed panning. Multiple rounds of panning are performed to enrich for antigen-specific scFv-phage. Monoclonal antibodies are subsequently identified by screening after each round of selection. The selected monoclonal scFv is cloned into an appropriate vector containing a Fc portion of interest and then produced in mammalian cells to generate an IgG like scFv-Fc fusion protein.
UniProt O15123
Research Area Growth Factors
Pathways RTK Signaling

Application Details

Product Details anti-Angiopoietin 2 Antibody Target Details Angiopoietin 2 Handling Images back to top
Comment

anti-Angiopoietin-2, mAb (rec.) (blocking) (Angy-2-1) is composed of human variable regions (VH and VL) (lambda-chain) of immunoglobulin fused to the mouse lgG2b Fc domain.

Restrictions For Research Use only

Handling

Product Details anti-Angiopoietin 2 Antibody Target Details Angiopoietin 2 Application Details Images back to top
Format Liquid
Concentration 1 mg/mL
Buffer In PBS containing 10 % glycerol and 0.02 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C.
Expiry Date 12 months