anti-Rat (Rattus) Angiopoietin 2 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended Angiopoietin 2 Antibody

Antigen
Angiopoietin 2 (ANGPT2) Antibodies
  • AGPT2
  • ANG2
  • Agpt2
  • Ang-2
  • Ang2
  • ang2
  • angpt2
  • ANGIOPOIETIN-2
  • ANG-2
  • ANGPT2
  • angiopoietin 2
  • angiopoietin 2b
  • ANGPT2
  • Angpt2
  • angpt2b
Epitope
AA 19-348
20
15
8
6
5
4
4
4
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
124
82
58
21
5
4
3
3
2
1
1
1
1
Host
Rabbit
140
15
6
2
1
1
Clonality
Polyclonal
Conjugate
This Angiopoietin 2 antibody is un-conjugated
15
7
6
4
4
4
4
4
4
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
106
63
61
21
18
15
13
10
8
7
7
2
2
Options

Available images

Catalog No. ABIN3043725
$ 280.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Clonality References Details
11.585577 ABIN1105366 IHC (p) WB Rabbit IgG C-Term Polyclonal 0
11.5 ABIN671781 IF (p) IHC (p) WB Rabbit IgG AA 450-490 Polyclonal 2
3.4755225 ABIN5945146 IHC IHC (p) WB Rabbit IgG AA 200-350 JM71-34 0
1 ABIN5556577 EIA IHC (p) WB Rabbit IgG C-Term Polyclonal 0
1 ABIN671790 IHC (p) WB HRP Rabbit IgG AA 450-490 Polyclonal 0
1 ABIN671783 IHC (p) WB Biotin Rabbit IgG AA 450-490 Polyclonal 0

General

Antigen Angiopoietin 2 (ANGPT2) Antibodies
Epitope AA 19-348
(20), (15), (8), (6), (5), (4), (4), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(124), (82), (58), (21), (5), (4), (3), (3), (2), (1), (1), (1), (1)
Host Rabbit
(140), (15), (6), (2), (1), (1)
Clonality
Polyclonal
Conjugate This Angiopoietin 2 antibody is un-conjugated
(15), (7), (6), (4), (4), (4), (4), (4), (4), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(106), (63), (61), (21), (18), (15), (13), (10), (8), (7), (7), (2), (2)
Pubmed 3 references available
Supplier

Product Details anti-Angiopoietin 2 Antibody

Target Details Angiopoietin 2 Application Details Handling References for anti-Angiopoietin 2 antibody (ABIN3043725) Images
Purpose Rabbit IgG polyclonal antibody for Angiopoietin-2(ANGPT2) detection. Tested with IHC-P in Human,Mouse,Rat.
Cross-Reactivity (Details) No cross reactivity with other proteins.
Characteristics Rabbit IgG polyclonal antibody for Angiopoietin-2(ANGPT2) detection. Tested with IHC-P in Human,Mouse,Rat.
Gene Name: angiopoietin 2
Protein Name: Angiopoietin-2
Purification Immunogen affinity purified.
Immunogen E.coli-derived human Angiopoietin 2 recombinant protein (Position: Y19-N348). Human Angiopoietin 2 shares 84% and 85% amino acid (aa) sequences identity with mouse and rat Angiopoietin 2, respectively.
Isotype IgG
Plasmids, Primers & others

Target Details Angiopoietin 2

Product Details anti-Angiopoietin 2 Antibody Application Details Handling References for anti-Angiopoietin 2 antibody (ABIN3043725) Images back to top
Antigen
Alternative Name ANGPT2 (ANGPT2 Antibody Abstract)
Background ANGPT2, also known as ANG2 or Angiopoietin 2, is a protein that in humans is encoded by the ANGPT2 gene. It is mapped to 8p23.1. ANGPT2 is a naturally occurring antagonist of ANG1 that competes for binding to the TIE2 receptor and blocks ANGPT1-induced TIE2 autophosphorylation during vasculogenesis. The encoded protein disrupts the vascular remodeling ability of ANGPT1 and may induce endothelial cell apoptosis. ANGPT2 was significantly increased in plasma and alveolar edema fluid in adults with acute lung injury compared to controls or patients with hydrostatic pulmonary edema, tracheal. ANGPT2 was also significantly increased in neonates with respiratory distress syndrome who developed bronchopulmonary edema. It is also a mediator of epithelial necrosis with an important role in hyperoxic acute lung injury and pulmonary edema.

Synonyms: AGPT 2 antibody|Agpt2 antibody|ANG 2 antibody|ANG-2 antibody|ANG2 antibody|ANG2 antibody|Angiopoietin 2a antibody|Angiopoietin 2B antibody|Angiopoietin-2 antibody|Angiopoietin2 antibody|ANGP2_HUMAN antibody|ANGPT 2 antibody|ANGPT2 antibody|ANGPT2 antibody|Tie2 ligand antibody
Gene ID 285
UniProt O15123
Pathways RTK Signaling

Application Details

Product Details anti-Angiopoietin 2 Antibody Target Details Angiopoietin 2 Handling References for anti-Angiopoietin 2 antibody (ABIN3043725) Images back to top
Application Notes IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
Comment

Antibody can be supported by ABIN921231 in IHC(P).

Restrictions For Research Use only

Handling

Product Details anti-Angiopoietin 2 Antibody Target Details Angiopoietin 2 Application Details References for anti-Angiopoietin 2 antibody (ABIN3043725) Images back to top
Format Lyophilized
Reconstitution Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
Concentration 500 μg/mL
Buffer Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

References for anti-Angiopoietin 2 antibody (ABIN3043725)

Product Details anti-Angiopoietin 2 Antibody Target Details Angiopoietin 2 Application Details Handling Images back to top
Product cited in:

Huang, Pan, Yu, Guo, Wang, Zhang, Wang, Gao: "Benefical therapeutic effect of Chinese Herbal Xinji'erkang formula on hypertension-induced renal injury in the 2-kidney-1-clip hypertensive rats." in: African journal of traditional, complementary, and alternative medicines : AJTCAM, Vol. 11, Issue 5, pp. 16-27, 2015

Bai, Li, Tian, Zhou: "Antiangiogenic treatment diminishes renal injury and dysfunction via regulation of local AKT in early experimental diabetes." in: PLoS ONE, Vol. 9, Issue 4, pp. e96117, 2014

Li, Fan, Song, Zhang, Chen, Li, Mi, Ma, Song, Tao, Li: "Expression of angiopoietin-2 and vascular endothelial growth factor receptor-3 correlates with lymphangiogenesis and angiogenesis and affects survival of oral squamous cell carcinoma." in: PLoS ONE, Vol. 8, Issue 9, pp. e75388, 2013

Images

Product Details anti-Angiopoietin 2 Antibody Target Details Angiopoietin 2 Application Details Handling References for anti-Angiopoietin 2 antibody (ABIN3043725) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-Angiopoietin 2 (ANGPT2) (AA 19-348) antibody (ABIN3043725) Anti-Angiopoietin 2 Picoband antibody, IHC(P): Rat Intestine Tissue
Immunohistochemistry (IHC) image for anti-Angiopoietin 2 (ANGPT2) (AA 19-348) antibody (ABIN3043725) Anti-Angiopoietin 2 Picoband antibody, IHC(P): Human Placenta Tissue
Immunohistochemistry (IHC) image for anti-Angiopoietin 2 (ANGPT2) (AA 19-348) antibody (ABIN3043725) Anti-Angiopoietin 2 Picoband antibody, IHC(P): Mouse Intestine Tissue