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|Antigen||Actin Related Protein 2/3 Complex, Subunit 1B, 41kDa (ARPC1B) Antibodies|
|Epitope||Middle Region Alternatives|
|Conjugate||This ARPC1B antibody is un-conjugated Alternatives|
Enzyme Immunoassay (EIA), Western Blotting (WB)
|1 reference available|
|Supplier||Log in to see|
Product Details anti-ARPC1B AntibodyTarget Details ARPC1B Application Details Handling References for anti-ARPC1B antibody (ABIN453520) Images
|Specificity||This antibody reacts to ARPC1B.|
|Purification||Affinity chromatography on Protein A|
|Immunogen||KLH conjugated synthetic peptide selected from the Center region of human ARPC1B|
Target Details ARPC1BProduct Details anti-ARPC1B Antibody Application Details Handling References for anti-ARPC1B antibody (ABIN453520) Images back to top
|Alternative Name||ARPC1B / ARC41 (ARPC1B Antibody Abstract)|
|Background||ARPC1B is one of seven subunits of the human Arp2/3 protein complex. This subunit is a member of the SOP2 family of proteins and is most similar to the protein encoded by gene ARPC1A. The similarity between these two proteins suggests that they both may function as p41 subunit of the human Arp2/3 complex that has been implicated in the control of actin polymerization in cells. It is possible that the p41 subunit is involved in assembling and maintaining the structure of the Arp2/3 complex.Synonyms: Actin-related protein 2/3 complex subunit 1B, Arp2/3 complex 41 kDa subunit, p41-ARC|
|Pathways||RTK Signaling, Regulation of Actin Filament Polymerization|
Application DetailsProduct Details anti-ARPC1B Antibody Target Details ARPC1B Handling References for anti-ARPC1B antibody (ABIN453520) Images back to top
ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-ARPC1B Antibody Target Details ARPC1B Application Details References for anti-ARPC1B antibody (ABIN453520) Images back to top
|Buffer||PBS with 0.09 % (W/V) sodium azide|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||Avoid repeated freezing and thawing.|
|Storage||4 °C/-20 °C|
|Storage Comment||Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.|
References for anti-ARPC1B antibody (ABIN453520)Product Details anti-ARPC1B Antibody Target Details ARPC1B Application Details Handling Images back to top
Volkmann, Amann, Stoilova-McPhie, Egile, Winter, Hazelwood, Heuser, Li, Pollard, Hanein: "Structure of Arp2/3 complex in its activated state and in actin filament branch junctions." in: Science (New York, N.Y.), Vol. 293, Issue 5539, pp. 2456-9, 2001
ImagesProduct Details anti-ARPC1B Antibody Target Details ARPC1B Application Details Handling References for anti-ARPC1B antibody (ABIN453520) back to top