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|Antigen||Brain-Derived Neurotrophic Factor (BDNF) Antibodies|
|Reactivity||Human, Rat (Rattus), Mouse (Murine) Alternatives|
|Conjugate||This BDNF antibody is un-conjugated Alternatives|
Immunohistochemistry (IHC), Western Blotting (WB)
|Supplier||Log in to see|
Product Details anti-BDNF AntibodyTarget Details BDNF Application Details Handling Images
|Specificity||Specific for mature BDNF.|
|Immunogen||Synthetic peptides (a dimer) from mature human BDNF (Brain derived neurotrophic factor) conjugated to an immunogenic carrier protein was used as the antigen.|
|Plasmids, Primers & others|
Target Details BDNFProduct Details anti-BDNF Antibody Application Details Handling Images back to top
|Alternative Name||BDNF (BDNF Antibody Abstract)|
Function: Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability.
Subunit: Monomers and homodimers. Binds to NTRK2/TRKB.
Subcellular location: Secreted. Also known as: Brain-derived neurotrophic factor, BDNF, Abrineurin.
|Pathways||RTK Signaling, Synaptic Membrane, Feeding Behaviour, Dicarboxylic Acid Transport, Regulation of long-term Neuronal Synaptic Plasticity|
Application DetailsProduct Details anti-BDNF Antibody Target Details BDNF Handling Images back to top
A dilution of 1 : 300 to 1 : 2000 is recommended.
The optimal dilution should be determined by the end user.
Not yet tested in other applications.
|Restrictions||For Research Use only|
HandlingProduct Details anti-BDNF Antibody Target Details BDNF Application Details Images back to top
|Reconstitution||Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.|
|Handling Advice||Avoid freeze and thaw cycles.|
|Storage||4 °C/-20 °C|
|Storage Comment||Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.|
|Expiry Date||12 months|
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