anti-Human DDR2 antibody for Immunohistochemistry

Recommended DDR2 Antibody (supplied by: Log in to see )

Antigen
Discoidin Domain Receptor tyrosine Kinase 2 (DDR2) Antibodies
  • MIG20a
  • NTRKR3
  • TKT
  • TYRO10
  • AW495251
  • Ntrkr3
  • tyro10
  • DDR2
  • Tyro10
  • ddr2
  • si:ch211-193c2.1
  • discoidin domain receptor tyrosine kinase 2
  • discoidin domain receptor family, member 2
  • discoidin domain receptor family, member 2, like
  • DDR2
  • Ddr2
  • ddr2l
Epitope
Center
15
13
11
10
8
6
4
2
2
2
2
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
90
33
6
1
1
Host
Rabbit
72
41
Clonality
Polyclonal
Conjugate
This DDR2 antibody is un-conjugated
4
4
4
4
4
4
2
2
2
2
2
2
2
Application
Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (IHC), Western Blotting (WB)
86
59
38
21
18
13
6
3
2
1
1
Options
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Catalog No. ABIN2855418
$ 358.60
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
8.907254 ABIN4899816 CyTOF FACS IHC Mouse IgG2b AA 24-399 Log in to see 290804 1
8.907254 ABIN969083 ICC IHC ELISA WB Mouse IgG2a Log in to see 3B11E4 3
8.907254 ABIN2469944 IF IHC ELISA WB Mouse IgG2a truncated Log in to see 0
8.907254 ABIN3030741 FACS IHC ELISA WB Rabbit Ig Fraction Log in to see Polyclonal 0
8.907254 ABIN1843313 ELISA IF/ICC IHC WB Mouse IgG2a Log in to see 0
8.907254 ABIN2432083 IHC ELISA Rabbit IgG Log in to see Polyclonal 0
8.907254 ABIN2426677 IHC ELISA Rabbit IgG Log in to see Polyclonal 0
1 ABIN449954 ICC IF IHC (p) IHC ELISA WB Mouse IgG2a Log in to see 3B11E4 0
1 ABIN2869259 ELISA ICC IHC WB Mouse IgG2a Log in to see 3B11E4 0
1 ABIN1867537 ICC IHC WB Rabbit IgG AA 578-817 Log in to see Polyclonal 0
1 ABIN2464044 IHC ELISA WB Mouse IgG2a truncated Log in to see 3B11E4 0
1 ABIN4304587 IHC IHC (p) WB Rabbit IgG C-Term Log in to see Polyclonal 0
1 ABIN4304588 FACS IHC IHC (p) WB Rabbit IgG Center Log in to see Polyclonal 0
1 ABIN5682664 ELISA ICC IF IHC IHC (p) WB Mouse IgG2a Log in to see 3B11E4 0
1 ABIN2251797 IHC ELISA WB Mouse IgG2a Log in to see 13B220 0
1 ABIN1582772 IF IHC WB Mouse IgG2a Log in to see 3B11E4 0
1 ABIN2251814 IF IHC ELISA WB Mouse IgG2a Log in to see 0
1 ABIN4901383 ELISA IF IHC WB Mouse IgG2a Log in to see 3B11E4 0
1 ABIN2138961 IF IHC ELISA WB Mouse IgG2a Log in to see 3B11E4 0
1 ABIN2764668 IHC (p) IHC ELISA WB Mouse IgG2a Log in to see 0

General

Antigen Discoidin Domain Receptor tyrosine Kinase 2 (DDR2) Antibodies
Epitope Center
(15), (13), (11), (10), (8), (6), (4), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine)
(90), (33), (6), (1), (1)
Host Rabbit
(72), (41)
Clonality
Polyclonal
Conjugate This DDR2 antibody is un-conjugated
(4), (4), (4), (4), (4), (4), (2), (2), (2), (2), (2), (2), (2)
Application Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (IHC), Western Blotting (WB)
(86), (59), (38), (21), (18), (13), (6), (3), (2), (1), (1)
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Product Details anti-DDR2 Antibody

Target Details DDR2 Application Details Handling Images
Cross-Reactivity Mouse (Murine), Cow (Bovine)
Cross-Reactivity (Details) Mouse (97 %), Bovine (98 %)
Characteristics Rabbit Polyclonal antibody to DDR2 (discoidin domain receptor tyrosine kinase 2)
DDR2 antibody [N2N3]
Purification Purified by antigen-affinity chromatography.
Immunogen Recombinant protein encompassing a sequence within the center region of human DDR2. The exact sequence is proprietary.
Isotype IgG

Target Details DDR2

Product Details anti-DDR2 Antibody Application Details Handling Images back to top
Antigen
Alternative Name DDR2 (DDR2 Antibody Abstract)
Background Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation, and metabolism. In several cases the biochemical mechanism by which RTKs transduce signals across the membrane has been shown to be ligand induced receptor oligomerization and subsequent intracellular phosphorylation. This autophosphorylation leads to phosphorylation of cytosolic targets as well as association with other molecules, which are involved in pleiotropic effects of signal transduction. RTKs have a tripartite structure with extracellular, transmembrane, and cytoplasmic regions. This gene encodes a member of a novel subclass of RTKs and contains a distinct extracellular region encompassing a factor VIII-like domain. Alternative splicing in the 5' UTR results in multiple transcript variants encoding the same protein.

Cellular Localization: Membrane
Molecular Weight 97 kDa
Gene ID 4921
Pathways RTK Signaling

Application Details

Product Details anti-DDR2 Antibody Target Details DDR2 Handling Images back to top
Application Notes Suggested dilution Reference Flow cytometry/FACS Assay-dependent dilution Immunohistochemistry Assay-dependent dilution IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceFlow cytometry/FACSAssay-dependent dilution ImmunohistochemistryAssay-dependent dilution IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
Comment

Positive Control: K562 , THP-1

Restrictions For Research Use only

Handling

Product Details anti-DDR2 Antibody Target Details DDR2 Application Details Images back to top
Format Liquid
Concentration 1 mg/mL
Buffer 0.1M Tris, 0.1M Glycine, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
Preservative Thimerosal (Merthiolate)
Precaution of Use This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Images

Product Details anti-DDR2 Antibody Target Details DDR2 Application Details Handling back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-Discoidin Domain Receptor tyrosine Kinase 2 (DDR2) (Center) antibody (ABIN2855418) IHC-P Image Immunohistochemical analysis of paraffin-embedded human hepatoma, using D...
Western Blotting (WB) image for anti-Discoidin Domain Receptor tyrosine Kinase 2 (DDR2) (Center) antibody (ABIN2855418) WB Image Sample (30 ug of whole cell lysate) A: THP-1 7.5% SDS PAGE antibody diluted ...