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|Antigen||EPH Receptor B1 (EPHB1) Antibodies|
|Conjugate||This EPH Receptor B1 antibody is un-conjugated Alternatives|
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Product Details anti-EPH Receptor B1 AntibodyTarget Details EPH Receptor B1 Application Details Handling Images
|Specificity||This antibody reacts to ephB1 (Elk receptor) - CY.|
Target Details EPH Receptor B1Product Details anti-EPH Receptor B1 Antibody Application Details Handling Images back to top
|Alternative Name||EPHB1 (EPHB1 Antibody Abstract)|
|Background||The immunogen used for the anti-human ephB1 (Elk receptor) - cytoplasmic(CY) region was a GST fusion protein ephB1 (Elk receptor) - CY corresponding to amino acid sequence 586 - 984 of the C terminus region and having a molecular weight of 116 kDa. EphB1, previously known as Elk (eph-like kinase), is a receptor tyrosine kinase of the highly tissue restricted family of eph proteins. EphB1 and other ephB family members are type 1 membrane spanning proteins, comprised of immunoglobulin, fibronectin type III, and cysteine rich subdomains in the ecto domain, and the single uninterrupted cytoplasmic tyrosine kinase domain upstream of a carboxyterminal sterile alpha motif (SAM) domain. EphB family proteins bind ephrins of the B class, ligands that are also transmembrane spanning proteins capable of transmitting signals. EphB1 is expressed predominantly in developing neural structures in embryos, and in vascular epithelium of kidney, and other tissues. Upon binding to alternatively oligomerized ephrin B1, ephB1 signals regulation of cell attachment and cell-cell assembly. Members of this protein family are implicated in neuronal and vascular cell targeting.Synonyms: ELK, EPH2, EPHT2, Ephrin type-B receptor 1, HEK6, NET, Tyrosine-protein kinase receptor EPH-2|
Application DetailsProduct Details anti-EPH Receptor B1 Antibody Target Details EPH Receptor B1 Handling Images back to top
Western Blot: 1 - 10 μg/mL. Immunoprecipitation: 10 - 20 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-EPH Receptor B1 Antibody Target Details EPH Receptor B1 Application Details Images back to top
|Buffer||Phosphate buffered saline with 0.08 % sodium azide|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||Avoid repeated freezing and thawing.|
ImagesProduct Details anti-EPH Receptor B1 Antibody Target Details EPH Receptor B1 Application Details Handling back to top