anti-Mouse (Murine) EPH Receptor B4 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended EPH Receptor B4 Antibody (supplied by: Log in to see )

Antigen
EPH Receptor B4 (EPHB4) Antibodies
  • htk
  • myk1
  • ephB4a
  • tyro11
  • ephb4b
  • MGC130997
  • AI042935
  • Htk
  • MDK2
  • Myk1
  • Tyro11
  • HTK
  • MYK1
  • TYRO11
  • EPH receptor B4
  • EPH receptor B4 L homeolog
  • EPH receptor B4 S homeolog
  • Eph receptor B4
  • EPHB4
  • ephb4.L
  • ephb4.S
  • ephb4
  • Ephb4
Reactivity
Human, Mouse (Murine)
151
65
9
1
1
1
1
Host
Rabbit
73
65
38
18
2
Clonality
Polyclonal
Conjugate
This EPH Receptor B4 antibody is un-conjugated
7
7
6
5
5
4
3
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
140
108
35
27
22
19
5
5
4
3
3
2
1
1
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

Submit your validation data for this product and get a full refund. I want to validate this product

Learn more

Available images

Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-EPH Receptor B4 (EPHB4) antibody (ABIN498286)
Western Blotting (WB) image for anti-EPH Receptor B4 (EPHB4) antibody (ABIN498286)
Catalog No. ABIN498286
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN2001181 IHC (p) ELISA Rabbit IgG AA 1-539 Log in to see Polyclonal 0
1 ABIN1537708 IHC (p) WB Rabbit Ig Fraction AA 88-118, Center Log in to see Polyclonal 0

General

Antigen EPH Receptor B4 (EPHB4) Antibodies
Reactivity Human, Mouse (Murine)
(151), (65), (9), (1), (1), (1), (1)
Host Rabbit
(73), (65), (38), (18), (2)
Clonality
Polyclonal
Conjugate This EPH Receptor B4 antibody is un-conjugated
(7), (7), (6), (5), (5), (4), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(140), (108), (35), (27), (22), (19), (5), (5), (4), (3), (3), (2), (1), (1), (1)
Supplier Log in to see

Product Details anti-EPH Receptor B4 Antibody

Target Details EPH Receptor B4 Application Details Handling Images
Specificity This antibody detects endogenous levels of EphB4 protein. (region surrounding Glu601)
Cross-Reactivity (Details) Species reactivity (tested):Human and Mouse.
Purification Affinity Chromatography using epitope-specific immunogen

Target Details EPH Receptor B4

Product Details anti-EPH Receptor B4 Antibody Application Details Handling Images back to top
Antigen
Alternative Name EPHB4 (EPHB4 Antibody Abstract)
Background EphB4, also known as Htk, Myk1, Tyro11, and Mdk2, is a member of the Eph receptor family, which binds of the ephrin ligand family. Two classes of receptors exist, designated A and B, that have an extracellular domain made up of a globular domain, a cysteine-rich domain, and two fibronectin type III domains, followed by the transmembrane region and cytoplasmic region. The cytoplasmic region contains juxtamembrane motif with two tyrosines, which are the major autophosphorylation sites, along with a kinase domain, and a conserved sterile alpha motif (SAM) in the carboxyl terminus, which includes one conserved tyrosine. Ligand recognition and binding leads to activation of intrinsic kinase activity. Only membrane-bound or Fc-clustered ligands have been shown to activate the receptor in vitro. Soluble monomeric ligands can bind the receptor, but do not induce receptor autophosphorylation and activation. The Eph receptors and ephrin ligands display reciprocal expression in vivo. Developing and adult neural tissue express nearly all of the Eph receptors and ephrin ligands.Ephs and ephrins play a significant role in angiogenesis.Synonyms: Ephrin type-B receptor 4, HTK, TYRO11, Tyrosine-protein kinase TYRO11, Tyrosine-protein kinase receptor HTK
Molecular Weight approx. 108.0 kDa
Gene ID 2050
NCBI Accession NP_004435
UniProt P54760
Pathways RTK Signaling

Application Details

Product Details anti-EPH Receptor B4 Antibody Target Details EPH Receptor B4 Handling Images back to top
Application Notes Western Blot: 1/500-1/1000. Immunofluorescence: 1/50-1/200. Immunohistochemistry on Paraffin Sections: 1/50-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-EPH Receptor B4 Antibody Target Details EPH Receptor B4 Application Details Images back to top
Concentration 1.0 mg/mL
Buffer PBS, pH ~7.2, 0.05 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Images

Product Details anti-EPH Receptor B4 Antibody Target Details EPH Receptor B4 Application Details Handling back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-EPH Receptor B4 (EPHB4) antibody (ABIN498286) Immunohistochemistry analysis of EphB4 Antibody in paraffin-embedded human bra...
Western Blotting (WB) image for anti-EPH Receptor B4 (EPHB4) antibody (ABIN498286) Western blot analysis of EphB4 Antibody in extracts from Jurkat cells.