General
Antigen
V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian) (ERBB4) Antibodies
Epitope
Internal Region
Alternatives
Reactivity
Bat, Gibbon, Hamster, Horse (Equine), Human, Monkey, Mouse (Murine)
Alternatives
Host
Rabbit
Alternatives
Clonality
Conjugate
This ERBB4 antibody is un-conjugated
Alternatives
Application
Immunohistochemistry (IHC)
Alternatives
Supplier
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Specificity
BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Purification
Immunoaffinity Chromatography
Immunogen
ERBB4 antibody was raised against a peptide located near the internal domain of ERBB4 (Human).
Antigen
Alternative Name
ERBB4 (ERBB4 Antibody Abstract )
Background
ERBB-4 receptor tyrosine kinase is activated by neuregulins, nrg- 2, nrg-3, heparin-binding egf-like growth factor, betacellulin and ntak to regulate cell proliferation and differentiation. Several isoforms of the ERBB-4 receptor tyrosine kinase have been identified and differ functionally in their response to phorbol ester: they represent cleavable and noncleavable forms of the receptor. These isoforms are differentially expressed in tissues.
Gene ID
2066
UniProt
Q15303
Pathways
RTK Signaling , Fc-epsilon Receptor Signaling Pathway , EGFR Signaling Pathway , Neurotrophin Signaling Pathway
Application Notes
ERBB4 antibody can be used in immunohistochemistry starting at 10 μg/mL, and immunofluorescence.
Restrictions
For Research Use only
Format
Liquid
Buffer
PBS, 0.1 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
As with all antibodies avoid freeze/thaw cycles.
Storage
4 °C/-80 °C
Storage Comment
ERBB4 antibody should be stored long term (months) at -80 °C and short term (days) at 4 °C.
Supplier Images
anti-V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian) (ERBB4) (Internal Region) antibody
anti-V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian) (ERBB4) (Internal Region) antibody