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|Antigen||Fibroblast Growth Factor 10 (FGF10) Antibodies|
|Epitope||AA 38-208 Alternatives|
|Conjugate||This FGF10 antibody is un-conjugated Alternatives|
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Product Details anti-FGF10 AntibodyTarget Details FGF10 Application Details Handling Images
Human FGF10 / KGF2
No cross-reactivity in ELISA with
E.coli cell lysate
|No Cross-Reactivity||Human, Escherichia coli (E. coli)|
|Characteristics||This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human FGF10 / KGF2 (rh FGF10 / KGF2, ABIN2003084 NP_004456.1, Gln 38-Ser 208,. The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.|
|Purification||purified by Protein A affinity chromatography|
|Sterility||0.2 μm filtered|
|Immunogen||Recombinant Human FGF10 / KGF2 protein (ABIN2003084)|
Target Details FGF10Product Details anti-FGF10 Antibody Application Details Handling Images back to top
|Alternative Name||FGF10 (FGF10 Antibody Abstract)|
|Background||The fibroblast growth factors (FGFs) are a growing family of heparin-binding growth factors that that regulate a variety of physiological processes in both developing and adult organism. The secreted human FGF10 exists most abundantly in the embyro and adult lung, and is most closely related to FGF7. It signaling through FGF receptor 2 (FGFR2) controls survival, proliferation, and differentiation of distal-alveolar epithelial progenitor cells during lung development. FGF10 overexpression during both the inflammatory and fibrotic phases results in a greatly reduced extent of lung fibrosis, suggesting that FGF10 may be useful as a novel approach to the treatment of pulmonary fibrosis. Additionally, FGF10 is also proposed as a growth factor active involved in the process of wound healing and limb bud formation. Human FGF10 shares approximately 92% and 95% amino acid sequence identity with mouse and rat FGF10, respectively.|
|Pathways||RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Tube Formation, Positive Regulation of Response to DNA Damage Stimulus|
Application DetailsProduct Details anti-FGF10 Antibody Target Details FGF10 Handling Images back to top
ELISA: 0.5-1 μg/mL
This antibody can be used at 0.5-1 μg/mL with the appropriate secondary reagents to detect Human FGF10. The detection limit for Human FGF10 is approximately 0.16 ng/well.
|Restrictions||For Research Use only|
HandlingProduct Details anti-FGF10 Antibody Target Details FGF10 Application Details Images back to top
|Buffer||0.2 μm filtered solution in PBS with 5 % trehalose|
|Handling Advice||Avoid repeated freeze-thaw cycles.|
|Storage||4 °C,-20 °C,-80 °C|
This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
|Expiry Date||12 months|