anti-Human FGFR4 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended FGFR4 Antibody (supplied by: Log in to see )

Antigen
Fibroblast Growth Factor Receptor 4 (FGFR4) Antibodies
  • FGFR4
  • XFGFR-4
  • XFGFR-4a
  • cd334
  • fgfr-4
  • jtk2
  • tkf
  • xfgfr4
  • CD334
  • JTK2
  • TKF
  • Fgfr-4
  • etID309818.21
  • wu:fc13h10
  • zgc:111935
  • fgfr-4c
  • fgfr4
  • fibroblast growth factor receptor 4
  • fibroblast growth factor receptor 4 S homeolog
  • FGFR4
  • fgfr4
  • Fgfr4
  • fgfr4.S
Epitope
Center
19
16
14
12
9
6
4
4
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
194
62
54
3
3
Host
Rabbit
133
66
10
Clonality
Polyclonal
Conjugate
This FGFR4 antibody is un-conjugated
9
8
7
5
4
3
2
2
2
2
2
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
161
104
58
34
30
26
13
10
8
7
5
3
2
1
1
1
Options
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Catalog No. ABIN2856017
$ 466.18
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
14.127748 ABIN3042391 IHC (p) WB Rabbit IgG AA 22-206 Log in to see Polyclonal 0
13 ABIN391970 FACS IF IHC (p) WB Rabbit Ig Fraction AA 24-55, N-Term Log in to see Polyclonal 1
12.579585 ABIN4901532 ELISA IHC (p) WB Mouse IgG1 Log in to see 4H2B10B2 0
11.127748 ABIN462135 ELISA IHC IHC (fro) IHC (p) WB Mouse IgG1 Log in to see 4H2B10B2 0
11.127748 ABIN1960119 IHC IHC (p) WB Mouse IgG1, kappa Log in to see 53CT32-19-3 0
10 ABIN5531164 FACS IF IHC (p) WB Rabbit Ig Fraction AA 24-55, N-Term Log in to see Polyclonal 0
10 ABIN5578119 IF IHC (p) WB Rabbit IgG Log in to see Polyclonal 0
10 ABIN3030961 IHC (p) WB Rabbit IgG AA 22-206 Log in to see Polyclonal 0
7 ABIN1997069 IHC (p) ELISA Rabbit IgG AA 1-369 Log in to see Polyclonal 0
7 ABIN671766 IF (p) IHC (p) WB Rabbit IgG AA 40-90 Log in to see Polyclonal 0
7 ABIN2851987 IHC (p) ELISA WB Mouse IgG1 kappa Log in to see 53CT32-19-3 0
7 ABIN5578115 ELISA IHC (p) WB Mouse IgG1 Log in to see 4H2B10B2 0
7 ABIN5578116 IHC (p) WB Mouse IgG1 kappa Log in to see 53CT32-19-3 0
7 ABIN5578117 IHC (p) WB Mouse IgG1 kappa Log in to see 53CT32-19-3 0
7 ABIN5578120 IF IHC (p) Rabbit IgG Log in to see Polyclonal 0
7 ABIN614490 EIA IHC (fro) IHC (p) WB Mouse IgG1 Log in to see 4H2B10B2 0
7 ABIN1106282 IHC (p) WB Mouse IgG1 Log in to see 4H2B10B2 2
1 ABIN5552242 EIA IHC (p) WB Rabbit Ig Fraction N-Term Log in to see Polyclonal 0
1 ABIN2620881 IHC IHC (p) WB Rabbit IgG AA 22-206 Log in to see Polyclonal 0
1 ABIN5550872 EIA IHC (p) WB Mouse IgG1 Log in to see 53CT32-19-3 0

General

Antigen Fibroblast Growth Factor Receptor 4 (FGFR4) Antibodies
Epitope Center
(19), (16), (14), (12), (9), (6), (4), (4), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine)
(194), (62), (54), (3), (3)
Host Rabbit
(133), (66), (10)
Clonality
Polyclonal
Conjugate This FGFR4 antibody is un-conjugated
(9), (8), (7), (5), (4), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(161), (104), (58), (34), (30), (26), (13), (10), (8), (7), (5), (3), (2), (1), (1), (1)
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Product Details anti-FGFR4 Antibody

Target Details FGFR4 Application Details Handling Images
Cross-Reactivity Cow (Bovine), Rat (Rattus)
Cross-Reactivity (Details) Rat (89 %), Bovine (92 %)
Characteristics Rabbit Polyclonal antibody to FGFR4 (fibroblast growth factor receptor 4)
FGFR4 antibody [N1N3]
Purification Purified by antigen-affinity chromatography.
Immunogen Recombinant protein encompassing a sequence within the center region of human FGFR4. The exact sequence is proprietary.
Isotype IgG
Plasmids, Primers & others

Target Details FGFR4

Product Details anti-FGFR4 Antibody Application Details Handling Images back to top
Antigen
Alternative Name FGFR4 (FGFR4 Antibody Abstract)
Background The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. The genomic organization of this gene, compared to members 1-3, encompasses 18 exons rather than 19 or 20. Although alternative splicing has been observed, there is no evidence that the C-terminal half of the IgIII domain of this protein varies between three alternate forms, as indicated for members 1-3. This particular family member preferentially binds acidic fibroblast growth factor and, although its specific function is unknown, it is overexpressed in gynecological tumor samples, suggesting a role in breast and ovarian tumorigenesis.

Cellular Localization: Membrane, Single-pass type I membrane protein
Molecular Weight 88 kDa
Gene ID 2264
Pathways RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding

Application Details

Product Details anti-FGFR4 Antibody Target Details FGFR4 Handling Images back to top
Application Notes Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
Comment

Positive Control: IMR32 , U87-MG

Restrictions For Research Use only

Handling

Product Details anti-FGFR4 Antibody Target Details FGFR4 Application Details Images back to top
Format Liquid
Concentration 0.67 mg/mL
Buffer 1XPBS, 1 % BSA, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
Preservative Thimerosal (Merthiolate)
Precaution of Use This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Images

Product Details anti-FGFR4 Antibody Target Details FGFR4 Application Details Handling back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-Fibroblast Growth Factor Receptor 4 (FGFR4) (Center) antibody (ABIN2856017) IHC-P Image Immunohistochemical analysis of paraffin-embedded Hela xenograft, using F...
Western Blotting (WB) image for anti-Fibroblast Growth Factor Receptor 4 (FGFR4) (Center) antibody (ABIN2856017) WB Image Sample (30 ug of whole cell lysate) A: U87-MG 7.5% SDS PAGE antibody diluted...
Immunohistochemistry (IHC) image for anti-Fibroblast Growth Factor Receptor 4 (FGFR4) (Center) antibody (ABIN2856017) IHC-P Image FGFR4 antibody [N1N3] detects FGFR4 protein at cytosol on mouse pancreas ...