anti-Cow (Bovine) HER2 antibody for Immunohistochemistry

Recommended HER2 Antibody (supplied by: Log in to see )

Antigen
V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) (ERBB2) Antibodies
  • CD340
  • HER-2
  • HER-2/neu
  • HER2
  • MLN 19
  • NEU
  • NGL
  • TKR1
  • Erbb-2
  • Neu
  • c-erbB2
  • c-neu
  • mKIAA3023
  • wu:fv70f10
  • zgc:63601
  • erb2
  • erb-b2 receptor tyrosine kinase 2
  • ERBB2
  • Erbb2
  • erbb2
Epitope
Cytoplasmic Domain
83
66
65
56
46
45
43
31
28
27
25
22
21
17
15
15
14
14
13
11
11
11
11
11
11
11
11
11
11
11
11
10
10
8
8
7
7
7
6
6
6
5
5
5
5
4
4
4
4
4
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Cow (Bovine), Gibbon, Gorilla, Hamster, Horse (Equine), Human, Monkey, Mouse (Murine), Rat (Rattus)
1141
396
277
28
21
7
4
4
3
3
3
2
2
2
1
1
1
Host
Rabbit
757
453
32
14
11
3
3
Clonality
Polyclonal
Conjugate
This HER2 antibody is un-conjugated
53
45
38
37
36
21
19
19
12
12
12
10
10
8
8
8
8
8
7
7
7
7
7
7
7
7
6
6
6
3
2
2
1
Application
Immunohistochemistry (IHC)
625
464
335
306
276
207
195
108
107
102
91
24
21
18
18
6
5
4
3
3
3
2
1
1
1
1
1
1
1
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Catalog No. ABIN2469527
$ 550.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN461702 IHC IHC (p) Rabbit N-Term Log in to see Polyclonal 0
1 ABIN213613 IHC IHC (p) Rabbit Cytoplasmic Domain Log in to see Polyclonal 0
1 ABIN2467627 IHC Rabbit N-Term Log in to see Polyclonal 0

General

Antigen V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) (ERBB2) Antibodies
Epitope Cytoplasmic Domain
(83), (66), (65), (56), (46), (45), (43), (31), (28), (27), (25), (22), (21), (17), (15), (15), (14), (14), (13), (11), (11), (11), (11), (11), (11), (11), (11), (11), (11), (11), (11), (10), (10), (8), (8), (7), (7), (7), (6), (6), (6), (5), (5), (5), (5), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Cow (Bovine), Gibbon, Gorilla, Hamster, Horse (Equine), Human, Monkey, Mouse (Murine), Rat (Rattus)
(1141), (396), (277), (28), (21), (7), (4), (4), (3), (3), (3), (2), (2), (2), (1), (1), (1)
Host Rabbit
(757), (453), (32), (14), (11), (3), (3)
Clonality
Polyclonal
Conjugate This HER2 antibody is un-conjugated
(53), (45), (38), (37), (36), (21), (19), (19), (12), (12), (12), (10), (10), (8), (8), (8), (8), (8), (7), (7), (7), (7), (7), (7), (7), (7), (6), (6), (6), (3), (2), (2), (1)
Application Immunohistochemistry (IHC)
(625), (464), (335), (306), (276), (207), (195), (108), (107), (102), (91), (24), (21), (18), (18), (6), (5), (4), (3), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1)
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Product Details anti-HER2 Antibody

Target Details HER2 Application Details Handling Images
Specificity BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Purification Immunoaffinity Chromatography
Immunogen ERBB2 antibody was raised against a peptide located in the cytoplasmic domain of ERBB2 (Human).

Target Details HER2

Product Details anti-HER2 Antibody Application Details Handling Images back to top
Antigen
Alternative Name ERBB2 (ERBB2 Antibody Abstract)
Background A tyrosine kinase receptor in the EGF-receptor family. ErbB2 does not bind ligand on its own, but acts as an amplifier in heterodimers with ErbB1, (EGFR), ErbB3, or ErbB4. Amplification of the ErbB2 gene and overexpression of ErbB2 protein is associated with breast cancer (~25 % of cases), and anti-ErbB2 therapeutics (e.g. Herceptin, an anti-ErbB2 monoclonal antibody) are sometimes effective in treating these cases. Overexpression of ErbB2 has also been indicated as a factor in prostate cancer.
Gene ID 2064
UniProt P04626
Pathways RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Skeletal Muscle Fiber Development

Application Details

Product Details anti-HER2 Antibody Target Details HER2 Handling Images back to top
Application Notes ERBB2 antibody can be used in ELISA starting at 1:10000, Western Blot starting at 1:500 - 1:2000, immunohistochemistry starting at 1:200, and immunofluorescence starting at 1:200 - 1:1000.
Restrictions For Research Use only

Handling

Product Details anti-HER2 Antibody Target Details HER2 Application Details Images back to top
Format Liquid
Buffer PBS, 0.1 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice As with all antibodies avoid freeze/thaw cycles.
Storage 4 °C/-80 °C
Storage Comment ERBB2 antibody should be stored long term (months) at -80 °C and short term (days) at 4 °C.

Images

Product Details anti-HER2 Antibody Target Details HER2 Application Details Handling back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) (ERBB2) (Cytoplasmic Domain) antibody (ABIN2469527) anti-V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) (ERBB2) (Cytoplasmic Domain) antibody