anti-Human MME antibody for Immunoprecipitation

Recommended MME Antibody (supplied by: Log in to see )

Antigen
Membrane Metallo-Endopeptidase (MME) Antibodies
  • CALLA
  • CD10
  • NEP
  • SFE
  • 6030454K05Rik
  • C85356
  • Nep
  • neprilysin
  • membrane metalloendopeptidase
  • membrane metallo endopeptidase
  • membrane metallo-endopeptidase
  • MME
  • Mme
Reactivity
Human
641
121
105
11
6
4
4
2
2
2
2
1
1
1
1
Host
Mouse
446
211
2
2
Clonality
Monoclonal
Conjugate
This MME antibody is conjugated to FITC
60
48
42
31
11
9
7
6
5
5
4
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunoprecipitation (IP)
357
280
213
136
114
92
86
39
35
21
16
13
4
4
4
2
2
2
1
1
1
1
1
1
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Catalog No. ABIN93932
$ 428.84
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
22.556313 ABIN948133 IP WB Rabbit AA 1-750 Log in to see Polyclonal 0
19.659819 ABIN93930 FACS IP Mouse IgG1 Log in to see MEM-78 4
19.659819 ABIN192081 FACS IP APC Mouse IgG1 Log in to see MEM-78 4
19.659819 ABIN93933 FACS IP PE Mouse IgG1 Log in to see MEM-78 4
19.659819 ABIN302051 FACS IP PerCP Mouse IgG1 Log in to see MEM-78 4
19.659819 ABIN93931 FACS IP Biotin Mouse IgG1 Log in to see MEM-78 4
19 ABIN2916843 IF/ICC IHC IP WB Rabbit AA 382-538 Log in to see Polyclonal 0
15.159819 ABIN2967161 FACS IP PE-DyLight 594 Mouse IgG1 Log in to see MEM-78 0
15.159819 ABIN5663573 IP IHC WB Rabbit Log in to see Polyclonal 0
11.5 ABIN4900407 CyTOF ELISA (Capture) FACS IHC IP WB Goat IgG AA 52-750 Log in to see Polyclonal 3
10 ABIN2916844 IF/ICC IHC IP WB Rabbit AA 565-750 Log in to see Polyclonal 0
5.5 ABIN2477961 IHC (fro) FACS IP WB Mouse IgG1 Log in to see SN5c 4
5.1514864 ABIN5682572 FACS IP Mouse IgG1 Log in to see MEM-78 0
4 ABIN119108 FACS IHC (fro) IP WB Mouse IgG1 Log in to see SN5c 2
4 ABIN119107 FACS IHC (fro) IP WB Mouse IgG1 Log in to see SN5c 2
4 ABIN119104 FACS IHC (fro) IP WB Mouse IgG1 Log in to see SN5c 2
4 ABIN1805404 FACS IHC IHC (fro) IP WB Mouse IgG1 Log in to see SN5c-L4-1A1 0
4 ABIN1876865 FACS IHC IP WB Rabbit IgG Log in to see Polyclonal 0
4 ABIN2662920 CMCD FACS IP IHC WB PE Mouse IgG1 kappa Log in to see HI10a 5
4 ABIN2664105 IP WB Mouse IgG1 kappa Log in to see HI10a 5

General

Antigen Membrane Metallo-Endopeptidase (MME) Antibodies
Reactivity Human
(641), (121), (105), (11), (6), (4), (4), (2), (2), (2), (2), (1), (1), (1), (1)
Host Mouse
(446), (211), (2), (2)
Clonality (Clone)
Monoclonal   ( )
Conjugate This MME antibody is conjugated to FITC
(60), (48), (42), (31), (11), (9), (7), (6), (5), (5), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Application Flow Cytometry (FACS), Immunoprecipitation (IP)
(357), (280), (213), (136), (114), (92), (86), (39), (35), (21), (16), (13), (4), (4), (4), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Pubmed 4 references available
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Product Details anti-MME Antibody

Target Details MME Application Details Handling References for anti-MME antibody (ABIN93932) Images
Specificity The antibody MEM-78 reacts with CD10 antigen (CALLA - Common acute lymphatic leukemia antigen), a 100 kDa type II integral membrane protein.
HLDA IV, WS Code B 506
HLDA V, WS Code B CD10.4
Cross-Reactivity (Details) Human
Immunogen NALM-6 human pre-B cell line
Clone MEM-78
Isotype IgG1
Plasmids, Primers & others

Target Details MME

Product Details anti-MME Antibody Application Details Handling References for anti-MME antibody (ABIN93932) Images back to top
Antigen
Alternative Name CD10 (MME Antibody Abstract)
Background CD10 (neutral endopeptidase –, NEP, common acute lymphocytic leukemia antigen –, CALLA, membrane metallo-endopeptidase –, MME, enkefalinase) is a 100- kDa cell surface zinc metalloprotease cleaving peptide bonds on the N-terminus of hydrophobic amino acids and inactivating multiple physiologically active peptids. CD10 is expressed on various normal cell types, including lymphoid precursor cells, germinal center B lymhocytes, and some epithelial cells, and its expression level serves as a marker for diagnostics of many carcinomas. CD10 is also a differentiation antigen for early B-lymphoid progenitors in the B-cell differentiation pathway and has a key role in regulation of growth, differentiation and signal transduction of many cellular systems.
Pathways RTK Signaling, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration

Application Details

Product Details anti-MME Antibody Target Details MME Handling References for anti-MME antibody (ABIN93932) Images back to top
Application Notes The reagent is designed for Flow Cytometry analysis of human blood cells using 20 μ,l reagent / 100 μ,l of whole blood or 106 cells in a suspension.The content of a vial (2 ml) is sufficient for 100 tests.
Comment

The purified antibody is conjugated with Fluorescein isothiocyanate (FITC) under optimum conditions. The reagent is free of unconjugated FITC and adjusted for direct use. No reconstitution is necessary.

Restrictions For Research Use only

Handling

Product Details anti-MME Antibody Target Details MME Application Details References for anti-MME antibody (ABIN93932) Images back to top
Reconstitution No reconstitution is necessary.
Buffer The reagent is provided in stabilizing phosphate buffered saline (PBS) solution containing 15 mM sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Do not freeze.
Avoid prolonged exposure to light.
Storage 4 °C
Storage Comment Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light. Do not use after expiration date stamped on vial label.

References for anti-MME antibody (ABIN93932)

Product Details anti-MME Antibody Target Details MME Application Details Handling Images back to top
Background publications

DallEra, True, Siegel, Porter, Sherertz, Liu: "Differential expression of CD10 in prostate cancer and its clinical implication." in: BMC urology, Vol. 7, pp. 3, 2007

Braham, Trimeche, Ziadi, Mestiri, Mokni, Amara, Hachana, Sriha, Korbi: "CD10 expression by fusiform stromal cells in nasopharyngeal carcinoma correlates with tumor progression." in: Virchows Archiv : an international journal of pathology, Vol. 449, Issue 2, pp. 220-4, 2006

Yada, Kashima, Daa, Kitano, Fujiwara, Yokoyama: "Expression of CD10 in basal cell carcinoma." in: The American Journal of dermatopathology, Vol. 26, Issue 6, pp. 463-71, 2004

Product cited in:

Angelisová, Drbal, Horejsí, Cerný: "Association of CD10/neutral endopeptidase 24.11 with membrane microdomains rich in glycosylphosphatidylinositol-anchored proteins and Lyn kinase." in: Blood, Vol. 93, Issue 4, pp. 1437-9, 1999

Images

Product Details anti-MME Antibody Target Details MME Application Details Handling References for anti-MME antibody (ABIN93932) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-Membrane Metallo-Endopeptidase (MME) antibody (FITC) (ABIN93932) Surface staining of NALM-6 human pre-B cell leukemia cell line with anti-human CD10 (...
Flow Cytometry (FACS) image for anti-Membrane Metallo-Endopeptidase (MME) antibody (FITC) (ABIN93932) Surface staining of human peripheral blood with anti-human CD10 (MEM-78) FITC.