anti-Cow (Bovine) SHC1 antibody for Western Blotting

Recommended SHC1 Antibody (supplied by: Log in to see )

Antigen
SHC (Src Homology 2 Domain Containing) Transforming Protein 1 (SHC1) Antibodies
  • SHC1
  • SHC
  • SHCA
  • P66shc
  • si:dkey-246i14.4
  • wu:fc10h03
  • shc
  • p66shc
  • Shc
  • ShcA
  • p66
  • SHC adaptor protein 1
  • Shc1p
  • squalene--hopene cyclase
  • SHC (Src homology 2 domain containing) transforming protein 1
  • SHC (Src homology 2 domain containing) transforming protein 1 L homeolog
  • src homology 2 domain-containing transforming protein C1
  • SHC1
  • shc1
  • Shc1
  • shc1.L
Epitope
C-Term
55
54
21
21
18
15
15
12
8
8
8
7
7
6
4
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Reactivity
Chicken, Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Rat (Rattus), Xenopus laevis, Zebrafish (Danio rerio)
299
234
177
12
12
9
8
7
3
3
3
3
2
1
1
1
1
Host
Rabbit
274
45
Clonality
Polyclonal
Conjugate
This SHC1 antibody is un-conjugated
9
9
8
5
5
5
5
5
5
5
5
5
5
5
2
2
2
1
Application
Western Blotting (WB)
239
121
90
77
66
58
20
19
11
9
8
4
3
1
Options
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Catalog No. ABIN928366
$ 473.93
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
7.8026066 ABIN2784202 WB Rabbit C-Term Log in to see Polyclonal 1
7.8026066 ABIN2957756 IHC WB Rabbit pTyr427 Log in to see Polyclonal 0
7.8026066 ABIN2707047 IHC WB Rabbit pTyr349 Log in to see Polyclonal 0
7.8026066 ABIN2972153 IHC WB KLH Rabbit IgG Center, pTyr349 Log in to see Polyclonal 0
4 ABIN321774 WB Rabbit IgG AA 371-420 Log in to see Polyclonal 0
1 ABIN214820 ELISA WB Mouse IgG1 pSer36 Log in to see 6E10 0
1 ABIN597686 WB Rabbit IgG pTyr349 Log in to see Polyclonal 0
1 ABIN602279 IHC WB Rabbit IgG pTyr427 Log in to see Polyclonal 0
1 ABIN597688 WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN198018 WB Mouse IgG1, kappa AA 314-320, pTyr317 Log in to see 0
1 ABIN2743434 IHC IHC (p) WB Rabbit pTyr349 Log in to see Polyclonal 0

General

Antigen SHC (Src Homology 2 Domain Containing) Transforming Protein 1 (SHC1) Antibodies
Epitope C-Term
(55), (54), (21), (21), (18), (15), (15), (12), (8), (8), (8), (7), (7), (6), (4), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Chicken, Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Rat (Rattus), Xenopus laevis, Zebrafish (Danio rerio)
(299), (234), (177), (12), (12), (9), (8), (7), (3), (3), (3), (3), (2), (1), (1), (1), (1)
Host Rabbit
(274), (45)
Clonality
Polyclonal
Conjugate This SHC1 antibody is un-conjugated
(9), (9), (8), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (2), (2), (2), (1)
Application Western Blotting (WB)
(239), (121), (90), (77), (66), (58), (20), (19), (11), (9), (8), (4), (3), (1)
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Product Details anti-SHC1 Antibody

Target Details SHC1 Application Details Handling Images
Cross-Reactivity Mouse (Murine), Rat (Rattus), Cow (Bovine), Frog, Chicken, Dog (Canine), Zebrafish (Brachydanio rerio)
Purification Purified
Immunogen SHC1 antibody was raised in rabbit using the C terminal of SHC1 as the immunogen
Plasmids, Primers & others

Target Details SHC1

Product Details anti-SHC1 Antibody Application Details Handling Images back to top
Antigen
Alternative Name SHC1 (SHC1 Antibody Abstract)
Background SHC1 is a signaling adapter that couples activated growth factor receptors to signaling pathway. Isoform p46Shc and isoform p52Shc, once phosphorylated, couple activated receptor tyrosine kinases to Ras via the recruitment of the GRB2/SOS complex and are implicated in the cytoplasmic propagation of mitogenic signals. Isoform p46Shc and isoform p52Shc may thus function as initiators of the Ras signaling cascade in various non-neuronal systems. Isoform p66Shc does not mediate Ras activation, but is involved in signal transduction pathways that regulate the cellular response to oxidative stress and life span. Isoform p66Shc acts as a downstream target of the tumor suppressor p53 and is indispensable for the ability of stress-activated p53 to induce elevation of intracellular oxidants, cytochrome c release and apoptosis. Synonyms: Polyclonal SHC1 antibody, Anti-SHC1 antibody, SHC, Src homology 2 domain containing transforming protein 1 antibody, FLJ26504 antibody, SHC antibody, SHCA antibody, p52SHC antibody, p66 antibody, p66SHC antibody.
Pathways RTK Signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, ER-Nucleus Signaling, Signaling Events mediated by VEGFR1 and VEGFR2

Application Details

Product Details anti-SHC1 Antibody Target Details SHC1 Handling Images back to top
Application Notes WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.
Comment

SHC1 Blocking Peptide, catalog no. 33R-1145, is also available for use as a blocking control in assays to test for specificity of this SHC1 antibody

Restrictions For Research Use only

Handling

Product Details anti-SHC1 Antibody Target Details SHC1 Application Details Images back to top
Format Lyophilized
Concentration Lot specific
Buffer Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
Handling Advice Avoid repeated freeze/thaw cycles.
Storage RT/-20 °C
Storage Comment Store at 4 °C, following reconstitution, aliquot and store at -20 °C.