anti-Rat (Meriones) SHC3 antibody for Western Blotting

Recommended SHC3 Antibody (supplied by: Log in to see )

Antigen
SHC (Src Homology 2 Domain Containing) Transforming Protein 3 (SHC3) Antibodies
  • N-Shc
  • NSHC
  • RAI
  • SHCC
  • ShcC
  • Rai
  • SHC adaptor protein 3
  • src homology 2 domain-containing transforming protein C3
  • SHC3
  • Shc3
Reactivity
Human, Mouse (Murine), Rat (Meriones)
60
41
36
4
4
4
4
4
2
2
1
Host
Rabbit
58
4
Clonality
Polyclonal
Conjugate
This SHC3 antibody is un-conjugated
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
35
22
15
13
9
4
3
2
1
1
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Catalog No. ABIN2801960
$ 335.50
Plus shipping costs $45.00

General

Antigen SHC (Src Homology 2 Domain Containing) Transforming Protein 3 (SHC3) Antibodies
Reactivity Human, Mouse (Murine), Rat (Meriones)
(60), (41), (36), (4), (4), (4), (4), (4), (2), (2), (1)
Host Rabbit
(58), (4)
Clonality
Polyclonal
Conjugate This SHC3 antibody is un-conjugated
(2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Western Blotting (WB)
(35), (22), (15), (13), (9), (4), (3), (2), (1), (1)
Pubmed 4 references available
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Product Details anti-SHC3 Antibody

Target Details SHC3 Application Details Handling References for anti-SHC3 antibody (ABIN2801960) Images
Isotype IgG
Plasmids, Primers & others

Target Details SHC3

Product Details anti-SHC3 Antibody Application Details Handling References for anti-SHC3 antibody (ABIN2801960) Images back to top
Antigen
Alternative Name SHC3 (SHC3 Antibody Abstract)
Background Signaling adapter that couples activated growth factor receptors to signaling pathway in neurons. Involved in the signal transduction pathways of neurotrophin-activated Trk receptors in cortical neurons.
Synonyms: SHC-transforming protein 3, Neuronal Shc, N-Shc, Protein Rai, SHC-transforming protein C, Src homology 2 domain-containing-transforming protein C3, SH2 domain protein C3, SHC3, NSHC, SHCC
Molecular Weight 64056 Da
Gene ID 53358
UniProt Q92529
Pathways RTK Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway

Application Details

Product Details anti-SHC3 Antibody Target Details SHC3 Handling References for anti-SHC3 antibody (ABIN2801960) Images back to top
Application Notes WB - 1:1000
Restrictions For Research Use only

Handling

Product Details anti-SHC3 Antibody Target Details SHC3 Application Details References for anti-SHC3 antibody (ABIN2801960) Images back to top
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

References for anti-SHC3 antibody (ABIN2801960)

Product Details anti-SHC3 Antibody Target Details SHC3 Application Details Handling Images back to top
Product cited in:

Humphray, Oliver, Hunt, Plumb, Loveland, Howe, Andrews, Searle, Hunt, Scott, Jones, Ainscough, Almeida, Ambrose, Ashwell, Babbage, Babbage, Bagguley, Bailey, Banerjee, Barker, Barlow, Bates, Beasley et al.: "DNA sequence and analysis of human chromosome 9. ..." in: Nature, Vol. 429, Issue 6990, pp. 369-74, 2004

Liu, Meakin: "ShcB and ShcC activation by the Trk family of receptor tyrosine kinases." in: The Journal of biological chemistry, Vol. 277, Issue 29, pp. 26046-56, 2002

Nakamura, Sanokawa, Sasaki, Ayusawa, Oishi, Mori: "N-Shc: a neural-specific adapter molecule that mediates signaling from neurotrophin/Trk to Ras/MAPK pathway." in: Oncogene, Vol. 13, Issue 6, pp. 1111-21, 1996

Pelicci, Dente, De Giuseppe, Verducci-Galletti, Giuli, Mele, Vetriani, Giorgio, Pandolfi, Cesareni, Pelicci: "A family of Shc related proteins with conserved PTB, CH1 and SH2 regions." in: Oncogene, Vol. 13, Issue 3, pp. 633-41, 1996

Images

Product Details anti-SHC3 Antibody Target Details SHC3 Application Details Handling References for anti-SHC3 antibody (ABIN2801960) back to top
Supplier Images
Western Blotting (WB) image for anti-SHC (Src Homology 2 Domain Containing) Transforming Protein 3 (SHC3) antibody (ABIN2801960) anti-SHC (Src Homology 2 Domain Containing) Transforming Protein 3 (SHC3) antibody