anti-Mouse (Murine) TRKA antibody for Western Blotting

Recommended TRKA Antibody (supplied by: Log in to see )

Antigen
Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1) Antibodies
  • MTC
  • TRK
  • TRK1
  • TRKA
  • Trk-A
  • p140-TrkA
  • Trk
  • C80751
  • Tkr
  • TrkA
  • trk
  • trka
  • CTRKA
  • trkA
  • neurotrophic receptor tyrosine kinase 1
  • neurotrophic tyrosine kinase, receptor, type 1
  • NTRK1
  • Ntrk1
  • ntrk1
Epitope
AA 342-361, Middle Region
55
25
20
17
15
15
15
14
13
13
12
12
12
12
10
10
10
10
10
8
8
7
7
6
6
5
4
4
4
4
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
424
262
208
2
2
Host
Rabbit
397
53
4
3
1
Clonality
Polyclonal
Conjugate
This TRKA antibody is un-conjugated
17
16
16
10
9
8
8
8
8
7
7
7
7
7
7
7
6
2
2
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
272
166
121
88
58
52
51
40
19
12
9
5
4
1
1
1
Options
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Catalog No. ABIN3044367
$ 280.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
3.080771 ABIN5518710 WB Rabbit IgG AA 71-90, N-Term Log in to see Polyclonal 2
3.080771 ABIN726110 IF (p) IHC (p) WB Rabbit IgG AA 740-796 Log in to see Polyclonal 1
3.080771 ABIN222983 IP IHC WB Rabbit IgG Log in to see Polyclonal 0
3.080771 ABIN2801358 IHC WB Rabbit C-Term Log in to see Polyclonal 0
3.080771 ABIN1532031 IHC ELISA WB Rabbit IgG AA 666-715, pTyr701 Log in to see Polyclonal 0
3.080771 ABIN1532032 ELISA WB Rabbit IgG AA 646-695, pTyr680 Log in to see Polyclonal 0
3.080771 ABIN1532422 ELISA WB Rabbit IgG AA 471-520 Log in to see Polyclonal 0
3.080771 ABIN392063 FACS WB Rabbit Ig Fraction AA 654-683, Center Log in to see Polyclonal 0
3.080771 ABIN5947442 FACS ICC IF IHC IHC (p) IP WB Rabbit IgG AA 750-850 Log in to see SU0354 0
3.080771 ABIN5947441 ICC IF IHC IHC (p) WB Rabbit IgG C-Term Log in to see JJ084-04 0
3.080771 ABIN659062 WB Mouse IgG1, kappa Log in to see 185CT47-6-1 0
3.080771 ABIN659061 WB Mouse IgG1, kappa Log in to see 185CT47-6-1 0
3.080771 ABIN6256787 ELISA IHC WB Rabbit IgG pTyr680, pTyr681 Log in to see Polyclonal 1
3.080771 ABIN2737768 ICC FACS IP IHC WB Rabbit IgG Log in to see Polyclonal 0
3.080771 ABIN652382 FACS IF WB Rabbit Ig Fraction Log in to see Polyclonal 0
3.080771 ABIN5692904 WB Rabbit Log in to see Polyclonal 0
3.080771 ABIN1846033 WB Rabbit pTyr680, pTyr681 Log in to see Polyclonal 0
3.080771 ABIN6255930 IHC WB Rabbit IgG pTyr490 Log in to see Polyclonal 0
3.080771 ABIN2987787 IF/ICC WB Rabbit IgG pSer791 Log in to see Polyclonal 0
3.080771 ABIN3031983 FACS ELISA WB Rabbit Ig Fraction AA 654-683 Log in to see Polyclonal 0

General

Antigen Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1) Antibodies
Epitope AA 342-361, Middle Region
(55), (25), (20), (17), (15), (15), (15), (14), (13), (13), (12), (12), (12), (12), (10), (10), (10), (10), (10), (8), (8), (7), (7), (6), (6), (5), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(424), (262), (208), (2), (2)
Host Rabbit
(397), (53), (4), (3), (1)
Clonality
Polyclonal
Conjugate This TRKA antibody is un-conjugated
(17), (16), (16), (10), (9), (8), (8), (8), (8), (7), (7), (7), (7), (7), (7), (7), (6), (2), (2), (1), (1), (1), (1)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(272), (166), (121), (88), (58), (52), (51), (40), (19), (12), (9), (5), (4), (1), (1), (1)
Pubmed 2 references available
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Product Details anti-TRKA Antibody

Target Details TRKA Application Details Handling References for anti-TRKA antibody (ABIN3044367) Images
Purpose Rabbit IgG polyclonal antibody for High affinity nerve growth factor receptor(NTRK1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Sequence RHGCLRLNQP THVNNGNYTL
Cross-Reactivity (Details) No cross reactivity with other proteins.
Characteristics Rabbit IgG polyclonal antibody for High affinity nerve growth factor receptor(NTRK1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: neurotrophic tyrosine kinase, receptor, type 1
Protein Name: High affinity nerve growth factor receptor
Purification Immunogen affinity purified.
Immunogen A synthetic peptide corresponding to a sequence in the middle region of human TrkA(342-361aa RHGCLRLNQPTHVNNGNYTL), identical to the related rat and mouse sequences.
Isotype IgG
Plasmids, Primers & others

Target Details TRKA

Product Details anti-TRKA Antibody Application Details Handling References for anti-TRKA antibody (ABIN3044367) Images back to top
Antigen
Alternative Name NTRK1 (NTRK1 Antibody Abstract)
Background Trk A(Neurotrophic tyrosine kinase receptor A) is the high affinity catalytic receptor for the neurotrophin, Nerve Growth Factor(NGF). Higher affinity binding of NGFR can achieved by association with higher molecular mass, low-affinity neurotrophin receptors, namely the tropomyosin receptor kinases, TRKA(NTRK1), TRKB(NTRK2), and TRKC(NTRK3). TRKA, TRKB, and TRKC are specific for or "preferred by" NGF, NTF4(Neurotrophin-4) and BDNF, and NTF3(Neurotrophin-3), respectively. NTF3 also binds to TRKA and TRKB, but with significantly lower affinity. The absence of TrkA(NGFR) expression was associated with a strong increase in the Sp3 repressor short isoform(s) and a lack of the Sp3 activator long isoform. Sp3 is a bifunctional transcription factor that has been reported to stimulate or repress the transcription of numerous genes. Indo et al.(1996) concluded that defects in TRKA cause CIPA(Congenital insensitivity to pain with anhidrosis) and that the NGF-TRKA system has a crucial role in the development and function of the nociceptive reception as well as establishment of thermoregulation via sweating in humans. These results also implicate genes encoding other TRK and neurotrophin family members as candidates for developmental defect(s) of the nervous system.

Synonyms: CIPA antibody|DKFZp781I14186 antibody|gp140trk antibody|High affinity nerve growth factor receptor antibody|High affinity nerve growth factor receptor precursor antibody|MTC antibody|neurotrophic tyrosine kinase receptor type 1 antibody|Ntrk 1 antibody|Ntrk1 antibody|NTRK1_HUMAN antibody|Oncogene TRK antibody|p140 TrkA antibody|p140-TrkA antibody|TRK 1 antibody|Trk A antibody|TRK antibody|Trk-A antibody|TRK1 antibody|TRK1 transforming tyrosine kinase protein antibody|TRK1-transforming tyrosine kinase protein antibody|Tropomyosin-related kinase A antibody|Tyrosine kinase receptor A antibody|Tyrosine kinase receptor antibody|Tyrosine Receptor Kinase A antibody
UniProt P04629
Pathways RTK Signaling, Neurotrophin Signaling Pathway, cAMP Metabolic Process

Application Details

Product Details anti-TRKA Antibody Target Details TRKA Handling References for anti-TRKA antibody (ABIN3044367) Images back to top
Application Notes WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
Comment

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions For Research Use only

Handling

Product Details anti-TRKA Antibody Target Details TRKA Application Details References for anti-TRKA antibody (ABIN3044367) Images back to top
Format Lyophilized
Reconstitution Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
Concentration 500 μg/mL
Buffer Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
Preservative Thimerosal (Merthiolate), Sodium azide
Precaution of Use This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
Expiry Date 12 months

References for anti-TRKA antibody (ABIN3044367)

Product Details anti-TRKA Antibody Target Details TRKA Application Details Handling Images back to top
Product cited in:

Li, Ma, Yi, Wang, Li, Liu, Sun, Chen, Yu, Li, Chen, Zhou: "The interactions between nerve growth factor and gonadotrophins in bovine oviduct." in: Animal reproduction science, Vol. 149, Issue 3-4, pp. 117-23, 2014

Li, Zhang, Zou, Xia, Bao: "Accumulation of nerve growth factor and its receptors in the uterus and dorsal root ganglia in a mouse model of adenomyosis." in: Reproductive biology and endocrinology : RB&E, Vol. 9, pp. 30, 2011

Images

Product Details anti-TRKA Antibody Target Details TRKA Application Details Handling References for anti-TRKA antibody (ABIN3044367) back to top
Supplier Images
Western Blotting (WB) image for anti-Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1) (AA 342-361), (Middle Region) antibody (ABIN3044367) Anti-TrkA antibody, Western blotting Lane 1: Rat Brain Tissue Lysate Lane 2: Mouse Br...
Immunohistochemistry (IHC) image for anti-Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1) (AA 342-361), (Middle Region) antibody (ABIN3044367) Anti-TrkA antibody, IHC(P) IHC(P): Rat Brain Tissue