anti-Rat (Rattus) TYRO3 antibody for Western Blotting

Recommended TYRO3 Antibody (supplied by: Log in to see )

Antigen
TYRO3 Protein Tyrosine Kinase (TYRO3) Antibodies
  • TYRO3
  • brt
  • byk
  • dtk
  • rse
  • sky
  • tif
  • Xksy
  • MGC145734
  • DKFZp469I0432
  • LOC100231598
  • BYK
  • Dtk
  • RSE
  • Sky
  • Tif
  • Brt
  • REK
  • ksy
  • xksy
  • AI323366
  • Etk-2
  • Rse
  • TYRO3 protein tyrosine kinase
  • TYRO3 protein tyrosine kinase L homeolog
  • TYRO3 protein tyrosine kinase 3
  • TYRO3
  • tyro3
  • Tyro3
  • tyro3.L
Reactivity
Human, Mouse (Murine), Rat (Rattus)
177
64
23
6
1
1
Host
Rabbit
110
69
18
Clonality
Polyclonal
Conjugate
This TYRO3 antibody is un-conjugated
5
5
5
4
4
4
4
4
4
3
3
3
2
2
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
123
72
49
45
39
25
24
20
12
10
5
4
2
2
1
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Available images

Catalog No. ABIN872341
$ 306.90
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN2747776 ELISA IP WB Rabbit IgG Log in to see Polyclonal 1
1 ABIN906157 IHC (p) WB HRP Rabbit IgG Log in to see Polyclonal 0
1 ABIN906162 IHC (p) WB Biotin Rabbit IgG Log in to see Polyclonal 0
1 ABIN5692934 ELISA FACS ICC IHC WB Rabbit AA 41-147 Log in to see Polyclonal 0
1 ABIN960394 WB Rabbit AA 470-520 Log in to see Polyclonal 0
1 ABIN4268615 WB Rabbit Log in to see Polyclonal 0
1 ABIN4268616 WB Rabbit Log in to see Polyclonal 0
1 ABIN2629701 WB Rabbit AA 854-878 Log in to see Polyclonal 0
1 ABIN2751867 ELISA IP WB FITC Rabbit IgG Log in to see Polyclonal 0
1 ABIN2151656 IHC ELISA WB Rabbit IgG pTyr749 Log in to see Polyclonal 0
1 ABIN2734697 EIA WB Rabbit IgG Log in to see Polyclonal 0

General

Antigen TYRO3 Protein Tyrosine Kinase (TYRO3) Antibodies
Reactivity Human, Mouse (Murine), Rat (Rattus)
(177), (64), (23), (6), (1), (1)
Host Rabbit
(110), (69), (18)
Clonality
Polyclonal
Conjugate This TYRO3 antibody is un-conjugated
(5), (5), (5), (4), (4), (4), (4), (4), (4), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(123), (72), (49), (45), (39), (25), (24), (20), (12), (10), (5), (4), (2), (2), (1)
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Product Details anti-TYRO3 Antibody

Target Details TYRO3 Application Details Handling Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human Tyrosine-protein kinase receptor TYRO3
Isotype IgG

Target Details TYRO3

Product Details anti-TYRO3 Antibody Application Details Handling Images back to top
Antigen
Alternative Name Tyro3 (TYRO3 Antibody Abstract)
Background

Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to several ligands including TULP1 or GAS6. Regulates many physiological processes including cell survival, migration and differentiation. Ligand binding at the cell surface induces dimerization and autophosphorylation of TYRO3 on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with PIK3R1 and thereby enhances PI3-kinase activity. Activates the AKT survival pathway, including nuclear translocation of NF-kappa-B and up-regulation of transcription of NF-kappa-B-regulated genes. TYRO3 signaling plays a role in various processes such as neuron protection from excitotoxic injury, platelet aggregation and cytoskeleton reorganization. Plays also an important role in inhibition of Toll-like receptors (TLRs)-mediated innate immune response by activating STAT1, which selectively induces production of suppressors of cytokine signaling SOCS1 and SOCS3.

Subcellular location: Extracellular

Synonyms: BYK, Dtk, RSE, Rek, Sky, Tif, Etk-2, Tyrosine-protein kinase receptor TYRO3, Tyrosine-protein kinase BYK, Tyrosine-protein kinase DTK, Tyrosine-protein kinase RSE, Tyrosine-protein kinase SKY, Tyrosine-protein kinase TIF, TYRO3

Gene ID 7301
UniProt Q06418
Pathways RTK Signaling

Application Details

Product Details anti-TYRO3 Antibody Target Details TYRO3 Handling Images back to top
Application Notes WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Restrictions For Research Use only

Handling

Product Details anti-TYRO3 Antibody Target Details TYRO3 Application Details Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

Images

Product Details anti-TYRO3 Antibody Target Details TYRO3 Application Details Handling back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-TYRO3 Protein Tyrosine Kinase (TYRO3) antibody (ABIN872341) Formalin-fixed and paraffin embedded rat brain labeled with Anti-TYRO3 Polyclonal Ant...