anti-Rat (Rattus) VEGFB antibody for Immunohistochemistry

Recommended VEGFB Antibody (supplied by: Log in to see )

Antigen
Vascular Endothelial Growth Factor B (VEGFB) Antibodies
  • VEGFL
  • VRF
  • VEGF-B
  • Vrf
  • vascular endothelial growth factor B
  • VEGFB
  • Vegfb
Reactivity
Mouse (Murine), Rat (Rattus), Human
164
74
58
5
5
5
2
1
1
1
Host
Rabbit
122
58
19
Clonality
Polyclonal
Conjugate
This VEGFB antibody is un-conjugated
14
13
6
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC), Western Blotting (WB)
175
100
69
49
14
11
11
9
8
2
1
1
1
Options
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Available images

Catalog No. ABIN3023000
€ 348.01
Plus shipping costs €45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
19.25679 ABIN3187464 ELISA IHC WB Rabbit IgG Internal Region Log in to see Polyclonal 0
19.13255 ABIN5692963 ELISA IHC WB Rabbit AA 22-207 Log in to see Polyclonal 0
13.132549 ABIN6265968 ELISA ICC IF IHC WB Rabbit IgG Log in to see Polyclonal 0
13.132549 ABIN1875323 IHC WB Rabbit IgG Log in to see Polyclonal 0
10.132549 ABIN6265966 ELISA IHC WB Rabbit IgG Log in to see Polyclonal 0
7 ABIN1078651 ICC IHC WB Rabbit IgG AA 21-137 Log in to see Polyclonal 0
7 ABIN2973512 IHC WB Rabbit IgG Log in to see Polyclonal 0
7 ABIN2905457 IF/ICC IHC IP WB Rabbit AA 21-137 Log in to see Polyclonal 0
7 ABIN5544849 IHC ELISA WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN2891733 IHC WB Rabbit Arg125 Log in to see Polyclonal 0
1 ABIN2880126 IHC WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN2894559 IHC WB Rabbit Log in to see Polyclonal 0
1 ABIN2384497 IC IHC ELISA WB Rabbit IgG AA 21-137 Log in to see Polyclonal 0
1 ABIN6091473 ELISA IHC WB Rabbit IgG AA 22-207 Log in to see Polyclonal 0
1 ABIN6104684 ELISA IHC WB Rabbit IgG Internal Region Log in to see Polyclonal 0
1 ABIN2905575 ELISA IHC WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN1994971 IHC WB Rabbit IgG Log in to see 0
1 ABIN618044 IHC WB Rabbit IgG C-Term Log in to see Polyclonal 0
1 ABIN2858470 IHC WB Rabbit Log in to see Polyclonal 0

General

Antigen Vascular Endothelial Growth Factor B (VEGFB) Antibodies
Reactivity Mouse (Murine), Rat (Rattus), Human
(164), (74), (58), (5), (5), (5), (2), (1), (1), (1)
Host Rabbit
(122), (58), (19)
Clonality
Polyclonal
Conjugate This VEGFB antibody is un-conjugated
(14), (13), (6), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (IHC), Western Blotting (WB)
(175), (100), (69), (49), (14), (11), (11), (9), (8), (2), (1), (1), (1)
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Product Details anti-VEGFB Antibody

Target Details VEGFB Application Details Handling Images
Purification Affinity purification
Immunogen Recombinant protein of human VEGFB
Isotype IgG
Plasmids, Primers & others

Target Details VEGFB

Product Details anti-VEGFB Antibody Application Details Handling Images back to top
Antigen
Alternative Name VEGFB (VEGFB Antibody Abstract)
Background Vascular endothelial growth factor (VEGF) is a highly specific mitogen for vascular endothelial cells. VEGF and its close relatives VEGF-B, -C and -D form a subfamily within PDGF family of growth factors, which belongs to the cysteine knot class of cytokines. Five VEGF isoforms of 121, 145, 165, 189 and 206 AAs (VEGF121-206) are generated as a result of alternative splicing from a single VEGF gene.The various VEGF forms bind to three tyrosine-kinase receptors, VEGFR-1, VEGFR-2 and VEGFR-3 which are expressed almost exclusively in endothelial cells. VEGFR-2 is the main angiogenic signal transducer for VEGF, while VEGFR-3 is specific for VEGF-C and -D and is necessary and sufficient for lymphangiogenic signaling. However, upon proteolytic processing VEGF-C and -D gain the ability to also bind and activate VEGFR-2. Guided by the binding properties of the ligands, the VEGFRs are able to form both homodimers and heterodimers. Receptor dimerization is accompanied by activation of receptor kinase activity leading to receptor autophosphorylation. Phosphorylated receptors recruit interacting proteins and induce downstream signaling. Recently, tumor therapies based on neutralizing anti-VEGF antibodies and small molecule tyrosine kinase inhibitors targeting VEGFRs have been developed. These new strategies for tumor treatment show the clinical relevance of inhibiting VEGF signal transduction pathways that are exaggerated in pathological angiogenesis.
Synonyms: VEGFB, VEGFL, VRF, Vascular endothelial growth factor B, VEGF-related factor
Gene ID 7423
UniProt P49765
Pathways RTK Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals

Application Details

Product Details anti-VEGFB Antibody Target Details VEGFB Handling Images back to top
Application Notes Recommended dilutions: WB: 1:500-1:2000, IHC: 1:50-1:200
Restrictions For Research Use only

Handling

Product Details anti-VEGFB Antibody Target Details VEGFB Application Details Images back to top
Format Liquid
Buffer PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid freeze / thaw cycles
Storage -20 °C/-80 °C

Images

Product Details anti-VEGFB Antibody Target Details VEGFB Application Details Handling back to top
Supplier Images
Western Blotting (WB) image for anti-Vascular Endothelial Growth Factor B (VEGFB) antibody (ABIN3023000) anti-Vascular Endothelial Growth Factor B (VEGFB) antibody
Immunohistochemistry (IHC) image for anti-Vascular Endothelial Growth Factor B (VEGFB) antibody (ABIN3023000) anti-Vascular Endothelial Growth Factor B (VEGFB) antibody (Image 2)