anti-Human VEGFC antibody for Immunohistochemistry (Frozen Sections)

Recommended VEGFC Antibody (supplied by: Log in to see )

Antigen
Vascular Endothelial Growth Factor C (VEGFC) Antibodies
  • VEGFC
  • vegf-c
  • xvegf-c
  • Flt4-L
  • VRP
  • AW228853
  • VEGF-C
  • vascular endothelial growth factor c
  • vascular endothelial growth factor C
  • vascular endothelial growth factor C S homeolog
  • vegfc
  • VEGFC
  • vegfc.S
  • Vegfc
Reactivity
Human
245
94
94
3
3
2
2
2
1
1
1
1
Host
Mouse
182
123
8
1
1
1
Clonality
Monoclonal
Conjugate
This VEGFC antibody is un-conjugated
30
25
19
8
7
7
5
5
4
4
4
4
4
4
4
4
4
3
3
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Frozen Sections) (IHC (fro)), Western Blotting (WB)
265
156
136
43
25
23
22
17
17
17
13
9
3
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Catalog No. ABIN1589951
$ 335.23
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN360866 IHC (fro) WB Mouse IgG2a Log in to see 9-00E-007 0

General

Antigen Vascular Endothelial Growth Factor C (VEGFC) Antibodies
Reactivity Human
(245), (94), (94), (3), (3), (2), (2), (2), (1), (1), (1), (1)
Host Mouse
(182), (123), (8), (1), (1), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This VEGFC antibody is un-conjugated
(30), (25), (19), (8), (7), (7), (5), (5), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (Frozen Sections) (IHC (fro)), Western Blotting (WB)
(265), (156), (136), (43), (25), (23), (22), (17), (17), (17), (13), (9), (3)
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Product Details anti-VEGFC Antibody

Target Details VEGFC Application Details Handling Images
Specificity Recombinant human VEGF-C
Cross-Reactivity Rat (Rattus)
Characteristics Chromosomal location: 11q13
This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse immunized with recombinant human VEGF-C recombinant protein).
Purification The IgG2a fraction of culture supernatant was purified by Protein G affinity chromatography.
Clone 9E7
Isotype IgG2a
Plasmids, Primers & others

Target Details VEGFC

Product Details anti-VEGFC Antibody Application Details Handling Images back to top
Antigen
Alternative Name VEGF-C (VEGFC Antibody Abstract)
Background VEGF-C, also known as Vascular Endothelial Growth Factor Related Protein (VRP), is a recently discovered VEGF growth factor family member that is most closely related to VEGF-D. The human VEGF-C cDNA encodes a pre-pro-protein of 416 amino acids residues. It is almost identical to the mouse VEGF-C protein. Similar to VEGF-D, VEGF-C has a VEGF homology domain spanning the middle third of the precursor molecule and long N- and C-terminal extensions. In adults, VEGF-C is highly expressed in heart, placenta, ovary and small intestine. Recombinant human VEGF-C, lacking the N- and C-terminal extensions and containing only the middle VEGF homology domain, forms primarily non-covalently linked dimers. This protein is a ligand for both VEGFR-2/KDR and VEGFR-3/FLT-4. Since VEGFR-3 is strongly expressed in lymphatic endothelial cells, it has been postulated that VEGF-C is involved in the regulation of the growth and/or differentiation of lymphatic endothelium. Although recombinant human VEGF-C is also a mitogen for vascular endothelial cells, it is much less potent than VEGF-A. The recombinant human VEGF-C contains 115 amino acids residues and was fused to a His-tag (6x His) at the C-terminal end. As a result of glycosylation VEGF-C migrates as an 18-24 kDa protein in SDS-PAGE under reducing conditions.
Synonyms: vascular endothelial growth factor C, VEGFC, VRP, Flt4-L
NCBI Accession NP_005420, NM_005429
UniProt P49767
Pathways RTK Signaling, Signaling Events mediated by VEGFR1 and VEGFR2

Application Details

Product Details anti-VEGFC Antibody Target Details VEGFC Handling Images back to top
Application Notes Western Blot: use at 1-5 µg/mL, IHC: use at 2-10µg/mL
Comment

Monoclonal Antibody

Restrictions For Research Use only

Handling

Product Details anti-VEGFC Antibody Target Details VEGFC Application Details Images back to top
Format Lyophilized
Reconstitution Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL.
Buffer PBS
Handling Advice Centrifuge vial prior to opening.
Storage -20 °C
Storage Comment The lyophilized antibody is stable at room temperature for up to 1 month. The reconstituted antibody is stable for at least two weeks at 2-8 °C. Frozen aliquots are stable for at least 6 months when stored at -20 °C.
Expiry Date 6 months