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|Antigen||Vascular Endothelial Growth Factor C (VEGFC) Antibodies|
|Epitope||N-Term, C-Term Alternatives|
|Reactivity||Human, Mouse (Murine) Alternatives|
|Conjugate||This VEGFC antibody is un-conjugated Alternatives|
Enzyme Immunoassay (EIA), Western Blotting (WB)
|Supplier||Log in to see|
Product Details anti-VEGFC AntibodyTarget Details VEGFC Application Details Handling Images
|Specificity||This antibody is specific to VEGFC.|
|Characteristics||Synonyms: VEGFC, VRP, Vascular endothelial growth factor C, Vascular endothelial growthfactor-related protein, Flt4 ligand|
|Purification||Protein G Chromatography eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.|
|Immunogen||This monoclonal antibody is generated from mice immunized with three KLH conjugatedsynthetic peptides selected from the N-terminal, central, and C-terminal regions of humanVEGF3.|
Target Details VEGFCProduct Details anti-VEGFC Antibody Application Details Handling Images back to top
|Alternative Name||VEGF-C / Flt4-L (VEGFC Antibody Abstract)|
|Background||VEGF-C (VEGF3) is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family, is active in angiogenesis and endothelial cell growth, and can also affect the permeability of blood vessels. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-3 receptors. Only the fully processed form can bind and activate VEGFR-2 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor D.Synonyms: Flt4 ligand, VEGFC, VRP, Vascular endothelial growth factor C, Vascular endothelial growth factor-related protein|
|Research Area||Cytokines, Growth Factors, Receptors, Immunology, Inflammation, Signaling|
|Pathways||RTK Signaling, Signaling Events mediated by VEGFR1 and VEGFR2|
Application DetailsProduct Details anti-VEGFC Antibody Target Details VEGFC Handling Images back to top
ELISA: 1/1,000Western blotting: 1/100-1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-VEGFC Antibody Target Details VEGFC Application Details Images back to top
|Buffer||PBS containing 0.09 % (W/V) Sodium Azide as preservative.|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Storage||4 °C/-20 °C|
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
|Expiry Date||12 months|
ImagesProduct Details anti-VEGFC Antibody Target Details VEGFC Application Details Handling back to top