anti-Mouse (Murine) VEGFR2 antibody for Western Blotting

Recommended VEGFR2 Antibody (supplied by: Log in to see )

Antigen
Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR) Antibodies
  • CD309
  • FLK1
  • VEGFR
  • VEGFR2
  • 6130401C07
  • Flk-1
  • Flk1
  • Krd-1
  • Ly73
  • VEGFR-2
  • sVEGFR-2
  • Vegfr-2
  • FLK-1
  • flk-1
  • vegfr-2
  • KDR
  • FLK/KDR
  • flk1
  • flk1b
  • kdrb
  • si:busm1-205d10.1
  • si:ch211-254j6.1
  • si:ch211-278f21.4
  • wu:fc31a09
  • kinase insert domain receptor
  • kinase insert domain protein receptor
  • vascular endothelial growth factor receptor kdr-like
  • kinase insert domain receptor (a type III receptor tyrosine kinase)
  • KDR
  • Kdr
  • LOC100136647
  • kdr
Reactivity
Human, Mouse (Murine), Rat (Rattus)
610
382
197
28
8
5
5
5
4
4
3
2
2
2
2
2
2
2
1
1
1
1
1
Host
Rabbit
545
144
57
4
2
1
1
Clonality
Polyclonal
Conjugate
This VEGFR2 antibody is un-conjugated
43
34
28
26
16
12
11
9
5
5
5
5
5
4
3
3
3
3
3
3
2
2
2
2
2
2
2
2
1
1
1
Application
ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
478
268
258
196
128
96
42
37
31
26
24
19
17
8
7
7
6
6
5
2
1
1
1
1
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Catalog No. ABIN6265973
$ 390.77
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
3.08196 ABIN152058 IHC (p) IP IHC WB Rabbit C-Term, AA 1158-1365 Log in to see Polyclonal 8
3.08196 ABIN2506667 ICC IF IHC (p) ELISA WB Rabbit IgG Log in to see Polyclonal 0
3.08196 ABIN783332 WB Rabbit AA 1057-1061 Log in to see Polyclonal 2
3.08196 ABIN2705327 IC IF IHC WB Rabbit C-Term, pTyr1175 Log in to see Polyclonal 0
3.08196 ABIN1531998 IHC ELISA WB Rabbit IgG AA 1141-1190, pTyr1175 Log in to see Polyclonal 1
3.08196 ABIN1532428 ELISA WB Rabbit IgG AA 1025-1074 Log in to see Polyclonal 1
3.08196 ABIN1533036 IHC ELISA WB Rabbit IgG AA 1141-1190 Log in to see Polyclonal 1
3.08196 ABIN1531999 IHC ELISA WB Rabbit IgG AA 1180-1229, pTyr1214 Log in to see Polyclonal 1
3.08196 ABIN1533037 IHC ELISA WB Rabbit IgG AA 1180-1229 Log in to see Polyclonal 1
3.08196 ABIN1531411 ELISA WB Rabbit IgG AA 1025-1074, pTyr1059 Log in to see Polyclonal 1
3.08196 ABIN1532000 IHC ELISA WB Rabbit IgG AA 917-966, pTyr951 Log in to see Polyclonal 0
3.08196 ABIN652371 FACS WB Rabbit Ig Fraction AA 1153-1182, Tyr1175 Log in to see Polyclonal 2
3.08196 ABIN1533038 IHC ELISA WB Rabbit IgG AA 917-966 Log in to see Polyclonal 0
3.08196 ABIN2180045 FACS IHC (p) WB Rabbit IgG AA 150-190 Log in to see Polyclonal 4
3.08196 ABIN3184634 ELISA IF IHC WB Rabbit IgG Ser696 Log in to see Polyclonal 0
3.08196 ABIN3182009 ELISA IHC WB Rabbit IgG pTyr1175 Log in to see Polyclonal 0
3.08196 ABIN3182010 ELISA IF IHC WB Rabbit IgG pTyr1214 Log in to see Polyclonal 0
3.08196 ABIN3184636 ELISA WB Rabbit IgG Ser70 Log in to see Polyclonal 0
3.08196 ABIN3184635 ELISA IF IHC WB Rabbit IgG Ser7 Log in to see Polyclonal 0
3.08196 ABIN151962 ICC IF WB Rabbit C-Term, AA 1300-1367 Log in to see Polyclonal 1

General

Antigen Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR) Antibodies
Reactivity Human, Mouse (Murine), Rat (Rattus)
(610), (382), (197), (28), (8), (5), (5), (5), (4), (4), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Host Rabbit
(545), (144), (57), (4), (2), (1), (1)
Clonality
Polyclonal
Conjugate This VEGFR2 antibody is un-conjugated
(43), (34), (28), (26), (16), (12), (11), (9), (5), (5), (5), (5), (5), (4), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Application ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
(478), (268), (258), (196), (128), (96), (42), (37), (31), (26), (24), (19), (17), (8), (7), (7), (6), (6), (5), (2), (1), (1), (1), (1)
Pubmed 5 references available
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Product Details anti-VEGFR2 Antibody

Target Details VEGFR2 Application Details Handling References for anti-VEGFR2 antibody (ABIN6265973) Images
Specificity VEGFR2 Antibody detects endogenous levels of total VEGFR2
Cross-Reactivity Human, Mouse (Murine), Rat (Rattus)
Purification The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
Immunogen A synthesized peptide derived from human VEGFR2
Isotype IgG
Plasmids, Primers & others

Target Details VEGFR2

Product Details anti-VEGFR2 Antibody Application Details Handling References for anti-VEGFR2 antibody (ABIN6265973) Images back to top
Antigen
Alternative Name VEGFR2 (KDR Antibody Abstract)
Background

Description: Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFC and VEGFD. Plays an essential role in the regulation of angiogenesis, vascular development, vascular permeability, and embryonic hematopoiesis. Promotes proliferation, survival, migration and differentiation of endothelial cells. Promotes reorganization of the actin cytoskeleton. Isoforms lacking a transmembrane domain, such as isoform 2 and isoform 3, may function as decoy receptors for VEGFA, VEGFC and/or VEGFD. Isoform 2 plays an important role as negative regulator of VEGFA- and VEGFC-mediated lymphangiogenesis by limiting the amount of free VEGFA and/or VEGFC and preventing their binding to FLT4. Modulates FLT1 and FLT4 signaling by forming heterodimers. Binding of vascular growth factors to isoform 1 leads to the activation of several signaling cascades. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate and the activation of protein kinase C. Mediates activation of MAPK1/ERK2, MAPK3/ERK1 and the MAP kinase signaling pathway, as well as of the AKT1 signaling pathway. Mediates phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, reorganization of the actin cytoskeleton and activation of PTK2/FAK1. Required for VEGFA-mediated induction of NOS2 and NOS3, leading to the production of the signaling molecule nitric oxide (NO) by endothelial cells. Phosphorylates PLCG1. Promotes phosphorylation of FYN, NCK1, NOS3, PIK3R1, PTK2/FAK1 and SRC.

Gene: KDR

Molecular Weight 180kDa
Gene ID 3791
UniProt P35968
Pathways RTK Signaling, Glycosaminoglycan Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling

Application Details

Product Details anti-VEGFR2 Antibody Target Details VEGFR2 Handling References for anti-VEGFR2 antibody (ABIN6265973) Images back to top
Application Notes WB 1:500-1:2000 IHC 1:50-1:200 IF 1:200
Restrictions For Research Use only

Handling

Product Details anti-VEGFR2 Antibody Target Details VEGFR2 Application Details References for anti-VEGFR2 antibody (ABIN6265973) Images back to top
Format Liquid
Concentration 1 mg/mL
Buffer PBS,  pH 7.4,50 % glycerol.

References for anti-VEGFR2 antibody (ABIN6265973)

Product Details anti-VEGFR2 Antibody Target Details VEGFR2 Application Details Handling Images back to top
Product cited in:

Zhang, Chen, Wang, Yang, Li, Wang, Liu, Ye: "Treatment of diabetes mellitus-induced erectile dysfunction using endothelial progenitor cells genetically modified with human telomerase reverse transcriptase." in: Oncotarget, Vol. 7, Issue 26, pp. 39302-39315, 2018

Gu: "IL13Rα2 siRNA inhibited cell proliferation, induced cell apoptosis, and suppressed cell invasion in papillary thyroid carcinoma cells." in: OncoTargets and therapy, Vol. 11, pp. 1345-1352, 2018

Wang, Shen, Liu, Ning, Wu, Huang: "TRIM24 siRNA induced cell apoptosis and reduced cell viability in human nasopharyngeal carcinoma cells." in: Molecular medicine reports, Vol. 18, Issue 1, pp. 369-376, 2018

Meng, Chen, Lei, Han, Zhong, Wang, Liu, Gao, Zhang, Tan, Liu, Zhou, Sun, Yang: "Hsp90β promotes aggressive vasculogenic mimicry via epithelial-mesenchymal transition in hepatocellular carcinoma." in: Oncogene, 2018

Wu, Zheng, Bai, Xia, Zhang, Guo: "HMGB1/RAGE axis mediates the apoptosis, invasion, autophagy, and angiogenesis of the renal cell carcinoma." in: OncoTargets and therapy, Vol. 11, pp. 4501-4510, 2018

Images

Product Details anti-VEGFR2 Antibody Target Details VEGFR2 Application Details Handling References for anti-VEGFR2 antibody (ABIN6265973) back to top
Supplier Images
Western Blotting (WB) image for anti-Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR) antibody (ABIN6265973) Western blot analysis of VEGFR2 expression in SK-OV3 whole cell lysates,The lane on t...
Immunofluorescence (fixed cells) (IF/ICC) image for anti-Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR) antibody (ABIN6265973) ABIN6269228 staining K562 by IF/ICC. The sample were fixed with PFA and permeabilized...
Immunohistochemistry (IHC) image for anti-Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR) antibody (ABIN6265973) ABIN6269228 at 1/50 staining human breast cancer tissue by IHC-P. The tissue was form...
Immunohistochemistry (IHC) image for anti-Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR) antibody (ABIN6265973) ABIN6269228 at 1/200 staining human breast cancer tissue sections by IHC-P. The tissu...
Western Blotting (WB) image for anti-Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR) antibody (ABIN6265973) Western blot analysis of extracts of various tissue sample,using VEGFR2 antibody.
Immunohistochemistry (IHC) image for anti-Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR) antibody (ABIN6265973) ABIN6269228 at 1/200 staining human breast cancer tissue sections by IHC-P. The tissu...