anti-Pig (Porcine) VEGFR2 antibody for Enzyme Immunoassay

Recommended VEGFR2 Antibody (supplied by: Log in to see )

Antigen
Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR) Antibodies
  • vegfr-2
  • KDR
  • 6130401C07
  • Flk-1
  • Flk1
  • Krd-1
  • Ly73
  • VEGFR-2
  • VEGFR2
  • sVEGFR-2
  • Vegfr-2
  • CD309
  • FLK1
  • VEGFR
  • FLK-1
  • flk-1
  • FLK/KDR
  • flk1
  • flk1b
  • kdrb
  • si:busm1-205d10.1
  • si:ch211-254j6.1
  • si:ch211-278f21.4
  • wu:fc31a09
  • fk52c05
  • flk
  • kdr
  • kdra
  • vegfr2
  • vegfr4
  • vegr2
  • wu:fk52c05
  • vascular endothelial growth factor receptor kdr-like
  • kinase insert domain protein receptor
  • kinase insert domain receptor
  • kinase insert domain receptor (a type III receptor tyrosine kinase)
  • kinase insert domain receptor like
  • LOC100136647
  • Kdr
  • KDR
  • kdr
  • kdrl
Epitope
3rd Extracellular Domain
76
60
56
39
25
23
22
21
18
18
16
15
15
15
13
13
13
12
12
11
11
10
9
7
6
6
6
5
5
4
4
4
4
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Pig (Porcine)
611
363
176
24
7
4
4
4
3
3
3
2
1
1
1
1
1
1
1
1
Host
Rat
532
144
59
4
2
2
1
Clonality
Monoclonal
Conjugate
This VEGFR2 antibody is un-conjugated
45
32
25
24
18
12
11
9
9
5
5
5
5
4
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
1
1
Application
Enzyme Immunoassay (EIA), Flow Cytometry (FACS)
462
242
212
202
120
109
42
34
26
25
18
17
11
9
9
8
7
6
5
2
1
1
1
1
1
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

Submit your validation data for this product and get a full refund. I want to validate this product

Learn more

Catalog No. ABIN5541982
$ 455.40
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN5541983 EIA FACS Rat IgG2a 2nd Extracellular Domain Log in to see BEP-5A1

General

Antigen Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR) Antibodies
Epitope 3rd Extracellular Domain
(76), (60), (56), (39), (25), (23), (22), (21), (18), (18), (16), (15), (15), (15), (13), (13), (13), (12), (12), (11), (11), (10), (9), (7), (6), (6), (6), (5), (5), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Pig (Porcine)
(611), (363), (176), (24), (7), (4), (4), (4), (3), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Host Rat
(532), (144), (59), (4), (2), (2), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This VEGFR2 antibody is un-conjugated
(45), (32), (25), (24), (18), (12), (11), (9), (9), (5), (5), (5), (5), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (1), (1)
Application Enzyme Immunoassay (EIA), Flow Cytometry (FACS)
(462), (242), (212), (202), (120), (109), (42), (34), (26), (25), (18), (17), (11), (9), (9), (8), (7), (6), (5), (2), (1), (1), (1), (1), (1), (1)
Supplier Log in to see

Product Details anti-VEGFR2 Antibody

Target Details VEGFR2 Application Details Handling Images
Specificity This antibody detects VEGFR2 (epitope on the third extracellular immunoglobulin-like domain).
Purification Protein G Chromatography
Immunogen genetic immunisation with cDNA encoding Human VEGFR2. Selection: based on recognition of the complete native protein expressed on transfected mammalian cells.
Clone BEP-5D8
Isotype IgG2a

Target Details VEGFR2

Product Details anti-VEGFR2 Antibody Application Details Handling Images back to top
Antigen
Alternative Name cd309,vegfr-2,flk-1 (KDR Antibody Abstract)
Background The vascular endothelial growth factor receptor-2 (VEGFR-2) plays an important role in the control of angiogenesis. This molecule is expressed on the surface of circulating endothelial stem cells as well as on adult vascular endothelial cells and other cell types (1). It is a 200- kDa type I transmembrane protein, consisting of a 19 amino acid leader peptide, a 744 amino acid extracellular domain made up of 7 immunoglobulin-like domains, a 24 amino acid transmembrane region and a 568 amino acid cytoplasmic domain. Interactions with VEGF ligands will stimulate angiogenesis, required in wound healing but also misused by tumours to promote their vascularization (2). The current monoclonal antibody was developed by genetic immunization against the complete extracellular domain of human VEGFR-2 and has been shown to be specific for the native target molecule and its counterpart in pigs using FACscan analyses on viable, transiently-transfected human BOSC23 cells (see Fig. 1). It binds to an epitope on the third extracellular immunoglobulin-like domain.
UniProt P35968
Pathways RTK Signaling, Glycosaminoglycan Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling

Application Details

Product Details anti-VEGFR2 Antibody Target Details VEGFR2 Handling Images back to top
Application Notes Flow Cytometry: 1.2 μg/10 6 cells. ELISA: 1/200-1/400. Cell based ELISA:
Restrictions For Research Use only

Handling

Product Details anti-VEGFR2 Antibody Target Details VEGFR2 Application Details Images back to top
Format Liquid
Buffer Phosphate buffered saline, pH 7.2
Storage 4 °C,-20 °C
Storage Comment Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Expiry Date 12 months