anti-Pig (Porcine) VEGFR2 antibody for Enzyme Immunoassay

Recommended VEGFR2 Antibody (supplied by: Log in to see )

Antigen
Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR) Antibodies
  • CD309
  • FLK1
  • VEGFR
  • VEGFR2
  • 6130401C07
  • Flk-1
  • Flk1
  • Krd-1
  • Ly73
  • VEGFR-2
  • sVEGFR-2
  • Vegfr-2
  • FLK-1
  • flk-1
  • vegfr-2
  • KDR
  • FLK/KDR
  • flk1
  • flk1b
  • kdrb
  • si:busm1-205d10.1
  • si:ch211-254j6.1
  • si:ch211-278f21.4
  • wu:fc31a09
  • kinase insert domain receptor
  • kinase insert domain protein receptor
  • vascular endothelial growth factor receptor kdr-like
  • kinase insert domain receptor (a type III receptor tyrosine kinase)
  • KDR
  • Kdr
  • LOC100136647
  • kdr
Epitope
3rd Extracellular Domain
65
60
57
39
25
23
22
19
16
16
15
15
15
13
13
12
12
11
10
10
10
9
7
6
6
6
6
5
5
5
4
4
4
4
4
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Pig (Porcine)
599
368
179
24
7
4
4
4
3
3
3
2
1
1
1
1
1
1
1
1
Host
Rat
520
146
59
4
2
1
1
Clonality
Monoclonal
Conjugate
This VEGFR2 antibody is un-conjugated
43
32
25
24
16
12
11
9
6
5
5
5
5
4
3
3
3
3
3
3
3
3
3
3
2
2
2
2
1
1
Application
Enzyme Immunoassay (EIA), Flow Cytometry (FACS)
459
250
219
201
125
103
42
30
26
25
18
17
11
9
9
8
7
6
5
2
1
1
1
1
1
1
Supplier
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Catalog No. ABIN5541982
$ 552.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN5541983 EIA FACS Rat IgG2a 2nd Extracellular Domain Log in to see BEP-5A1 0

General

Antigen Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR) Antibodies
Epitope 3rd Extracellular Domain
(65), (60), (57), (39), (25), (23), (22), (19), (16), (16), (15), (15), (15), (13), (13), (12), (12), (11), (10), (10), (10), (9), (7), (6), (6), (6), (6), (5), (5), (5), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Pig (Porcine)
(599), (368), (179), (24), (7), (4), (4), (4), (3), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Host Rat
(520), (146), (59), (4), (2), (1), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This VEGFR2 antibody is un-conjugated
(43), (32), (25), (24), (16), (12), (11), (9), (6), (5), (5), (5), (5), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (1), (1)
Application Enzyme Immunoassay (EIA), Flow Cytometry (FACS)
(459), (250), (219), (201), (125), (103), (42), (30), (26), (25), (18), (17), (11), (9), (9), (8), (7), (6), (5), (2), (1), (1), (1), (1), (1), (1)
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Product Details anti-VEGFR2 Antibody

Target Details VEGFR2 Application Details Handling Images
Specificity This antibody detects VEGFR2 (epitope on the third extracellular immunoglobulin-like domain).
Purification Protein G Chromatography
Immunogen genetic immunisation with cDNA encoding Human VEGFR2. Selection: based on recognition of the complete native protein expressed on transfected mammalian cells.
Clone BEP-5D8
Isotype IgG2a

Target Details VEGFR2

Product Details anti-VEGFR2 Antibody Application Details Handling Images back to top
Antigen
Alternative Name cd309,vegfr-2,flk-1 (KDR Antibody Abstract)
Background The vascular endothelial growth factor receptor-2 (VEGFR-2) plays an important role in the control of angiogenesis. This molecule is expressed on the surface of circulating endothelial stem cells as well as on adult vascular endothelial cells and other cell types (1). It is a 200- kDa type I transmembrane protein, consisting of a 19 amino acid leader peptide, a 744 amino acid extracellular domain made up of 7 immunoglobulin-like domains, a 24 amino acid transmembrane region and a 568 amino acid cytoplasmic domain. Interactions with VEGF ligands will stimulate angiogenesis, required in wound healing but also misused by tumours to promote their vascularization (2). The current monoclonal antibody was developed by genetic immunization against the complete extracellular domain of human VEGFR-2 and has been shown to be specific for the native target molecule and its counterpart in pigs using FACscan analyses on viable, transiently-transfected human BOSC23 cells (see Fig. 1). It binds to an epitope on the third extracellular immunoglobulin-like domain.
UniProt P35968
Pathways RTK Signaling, Glycosaminoglycan Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling

Application Details

Product Details anti-VEGFR2 Antibody Target Details VEGFR2 Handling Images back to top
Application Notes Flow Cytometry: 1.2 μg/10 6 cells. ELISA: 1/200-1/400. Cell based ELISA:
Restrictions For Research Use only

Handling

Product Details anti-VEGFR2 Antibody Target Details VEGFR2 Application Details Images back to top
Format Liquid
Buffer Phosphate buffered saline, pH 7.2
Storage 4 °C,-20 °C
Storage Comment Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Expiry Date 12 months