anti-Rat (Rattus) VEGFR2 antibody for Flow Cytometry

Recommended VEGFR2 Antibody (supplied by: Log in to see )

Antigen
Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR) Antibodies
  • CD309
  • FLK1
  • VEGFR
  • VEGFR2
  • 6130401C07
  • Flk-1
  • Flk1
  • Krd-1
  • Ly73
  • VEGFR-2
  • sVEGFR-2
  • Vegfr-2
  • FLK-1
  • flk-1
  • vegfr-2
  • KDR
  • FLK/KDR
  • flk1
  • flk1b
  • kdrb
  • si:busm1-205d10.1
  • si:ch211-254j6.1
  • si:ch211-278f21.4
  • wu:fc31a09
  • kinase insert domain receptor
  • kinase insert domain protein receptor
  • vascular endothelial growth factor receptor kdr-like
  • kinase insert domain receptor (a type III receptor tyrosine kinase)
  • KDR
  • Kdr
  • LOC100136647
  • kdr
Epitope
AA 150-190
79
61
56
40
27
24
24
22
21
21
19
15
15
15
14
12
12
10
10
9
8
7
7
7
7
6
6
6
6
5
5
5
5
4
4
4
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Pig (Porcine), Rat (Rattus)
760
412
212
27
14
8
5
5
5
4
3
2
2
2
2
2
2
2
1
1
1
1
1
Host
Rabbit
578
265
72
4
2
1
1
Clonality
Polyclonal
Conjugate
This VEGFR2 antibody is un-conjugated
52
39
33
32
23
22
19
13
13
13
12
11
9
9
8
8
8
8
6
6
5
5
5
5
4
3
3
3
3
3
3
2
2
2
2
2
1
1
1
Application
Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
587
331
329
296
232
156
143
60
44
31
26
19
17
8
7
7
6
6
5
2
1
1
1
1
Options
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Catalog No. ABIN2180045
$ 329.45
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
17.059835 ABIN152343 CyTOF ELISA FACS ICC IF IHC IHC (p) WB Mouse IgG1 Log in to see EIC 2
1 ABIN355020 ELISA FACS IHC IHC (fro) Mouse IgG1 Log in to see 0
1 ABIN2180046 FACS Alexa Fluor 350 Rabbit IgG AA 150-190 Log in to see Polyclonal 0
1 ABIN2180047 FACS Alexa Fluor 488 Rabbit IgG AA 150-190 Log in to see Polyclonal 0
1 ABIN2180048 FACS Alexa Fluor 555 Rabbit IgG AA 150-190 Log in to see Polyclonal 0
1 ABIN2180049 FACS Alexa Fluor 647 Rabbit IgG AA 150-190 Log in to see Polyclonal 0
1 ABIN2180050 FACS Cy3 Rabbit IgG AA 150-190 Log in to see Polyclonal 0
1 ABIN2180052 FACS Cy5.5 Rabbit IgG AA 150-190 Log in to see Polyclonal 0
1 ABIN2180054 FACS FITC Rabbit IgG AA 150-190 Log in to see Polyclonal 0
1 ABIN2180051 FACS Cy5 Rabbit IgG AA 150-190 Log in to see Polyclonal 0
1 ABIN2180053 FACS Cy7 Rabbit IgG AA 150-190 Log in to see Polyclonal 0
1 ABIN2180055 FACS PE Rabbit IgG AA 150-190 Log in to see Polyclonal 0
1 ABIN2808355 FACS Alexa Fluor 594 Rabbit IgG AA 150-190 Log in to see Polyclonal 0
1 ABIN5012366 FACS Alexa Fluor 750 Rabbit IgG AA 150-190 Log in to see Polyclonal 0
1 ABIN5012365 FACS Alexa Fluor 680 Rabbit IgG AA 150-190 Log in to see Polyclonal 0
1 ABIN6048854 FACS PE Rabbit IgG Log in to see Polyclonal 0
1 ABIN6048396 FACS APC Rabbit IgG Log in to see Polyclonal 0
1 ABIN6047938 FACS FITC Rabbit IgG Log in to see Polyclonal 0
1 ABIN6047348 FACS Rabbit IgG Log in to see Polyclonal 0
-2.440165 ABIN4365134 FACS APC Mouse IgG1 Log in to see EIC 0

General

Antigen Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR) Antibodies
Epitope AA 150-190
(79), (61), (56), (40), (27), (24), (24), (22), (21), (21), (19), (15), (15), (15), (14), (12), (12), (10), (10), (9), (8), (7), (7), (7), (7), (6), (6), (6), (6), (5), (5), (5), (5), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Pig (Porcine), Rat (Rattus)
(760), (412), (212), (27), (14), (8), (5), (5), (5), (4), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Host Rabbit
(578), (265), (72), (4), (2), (1), (1)
Clonality
Polyclonal
Conjugate This VEGFR2 antibody is un-conjugated
(52), (39), (33), (32), (23), (22), (19), (13), (13), (13), (12), (11), (9), (9), (8), (8), (8), (8), (6), (6), (5), (5), (5), (5), (4), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1)
Application Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(587), (331), (329), (296), (232), (156), (143), (60), (44), (31), (26), (19), (17), (8), (7), (7), (6), (6), (5), (2), (1), (1), (1), (1)
Pubmed 4 references available
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Product Details anti-VEGFR2 Antibody

Target Details VEGFR2 Application Details Handling References for anti-VEGFR2 antibody (ABIN2180045) Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human VEGFR2
Isotype IgG
Plasmids, Primers & others

Target Details VEGFR2

Product Details anti-VEGFR2 Antibody Application Details Handling References for anti-VEGFR2 antibody (ABIN2180045) Images back to top
Antigen
Alternative Name Vegfr2 (KDR Antibody Abstract)
Background

Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFC and VEGFD. Plays an essential role in the regulation of angiogenesis, vascular development, vascular permeability, and embryonic hematopoiesis. Promotes proliferation, survival, migration and differentiation of endothelial cells. Promotes reorganization of the actin cytoskeleton. Isoforms lacking a transmembrane domain, such as isoform 2 and isoform 3, may function as decoy receptors for VEGFA, VEGFC and/or VEGFD. Isoform 2 plays an important role as negative regulator of VEGFA- and VEGFC-mediated lymphangiogenesis by limiting the amount of free VEGFA and/or VEGFC and preventing their binding to FLT4. Modulates FLT1 and FLT4 signaling by forming heterodimers. Binding of vascular growth factors to isoform 1 leads to the activation of several signaling cascades. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate and the activation of protein kinase C. Mediates activation of MAPK1/ERK2, MAPK3/ERK1 and the MAP kinase signaling pathway, as well as of the AKT1 signaling pathway. Mediates phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, reorganization of the actin cytoskeleton and activation of PTK2/FAK1. Required for VEGFA-mediated induction of NOS2 and NOS3, leading to the production of the signaling molecule nitric oxide (NO) by endothelial cells. Phosphorylates PLCG1. Promotes phosphorylation of FYN, NCK1, NOS3, PIK3R1, PTK2/FAK1 and SRC.

Subcellular location: Extracellular

Synonyms: FLK1, CD309, VEGFR, VEGFR2, Vascular endothelial growth factor receptor 2, VEGFR-2, Fetal liver kinase 1, FLK-1, Kinase insert domain receptor, KDR, Protein-tyrosine kinase receptor flk-1

Gene ID 3791
UniProt P35968
Pathways RTK Signaling, Glycosaminoglycan Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling

Application Details

Product Details anti-VEGFR2 Antibody Target Details VEGFR2 Handling References for anti-VEGFR2 antibody (ABIN2180045) Images back to top
Application Notes WB 1:100-1000
FCM 1:20-100
IHC-P 1:100-500
Restrictions For Research Use only

Handling

Product Details anti-VEGFR2 Antibody Target Details VEGFR2 Application Details References for anti-VEGFR2 antibody (ABIN2180045) Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

References for anti-VEGFR2 antibody (ABIN2180045)

Product Details anti-VEGFR2 Antibody Target Details VEGFR2 Application Details Handling Images back to top
Product cited in:

Wang, Chen, Ke, Li: "Ghrelin inhibits atherosclerotic plaque angiogenesis and promotes plaque stability in a rabbit atherosclerotic model." in: Peptides, Vol. 90, pp. 17-26, 2017 Method employed by authors: Western Blotting (WB), Western Blotting (WB) (Sample species: Rabbit). Further details: Sample: abdominal aorta

Tan, Yang, Fu, Cui, Guo, Ma, Yin, Leng, Song: "Single-dose local simvastatin injection improves implant fixation via increased angiogenesis and bone formation in an ovariectomized rat model." in: Medical science monitor : international medical journal of experimental and clinical research, Vol. 21, pp. 1428-39, 2015 Method employed by authors: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Sample species: Rat (Rattus)).

García Fernández, Sánchez Pérez, Sánchez Maldonado, García-Palencia, Naranjo Freixa, Palomo Yagüe, Flores: "Iberian pig early pregnancy: vascular endothelial growth factor receptor system expression in the maternofetal interface in healthy and arresting conceptuses." in: Theriogenology, Vol. 83, Issue 3, pp. 334-43, 2014 Method employed by authors: Western Blotting (WB) (Sample species: Pig (Porcine)).

Kuang, Yang, Zhang, Zhang, Wu: "Schlafen 1 inhibits the proliferation and tube formation of endothelial progenitor cells." in: PLoS ONE, Vol. 9, Issue 10, pp. e109711, 2014 (Sample species: Rat (Rattus)).

Images

Product Details anti-VEGFR2 Antibody Target Details VEGFR2 Application Details Handling References for anti-VEGFR2 antibody (ABIN2180045) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR) (AA 150-190) antibody (ABIN2180045) HeLa cells probed with Rabbit Anti-VEGFR2 Polyclonal Antibody (ABIN2180045) at 1:100 ...
Western Blotting (WB) image for anti-Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR) (AA 150-190) antibody (ABIN2180045) Mouse lung lysates probed with Anti-VEGFR2 Polyclonal Antibody at 1:5000 90min in 37˚C.
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR) (AA 150-190) antibody (ABIN2180045) Formalin-fixed and paraffin embedded mouse placenta tissue labeled with Anti-VEGFR2 P...