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Sphingosine-1-Phosphate Receptor 5 Products

(Sphingosine-1-Phosphate Receptor 5 (S1PR5))

Categories

The lysosphingolipid sphingosine 1-phosphate (S1P) regulates cell proliferation, apoptosis, motility, and neurite retraction. Its actions may be both intracellular as a second messenger and extracellular as a receptor ligand. S1P and the structurally related lysolipid mediator lysophosphatidic acid (LPA) signal cells through a set of G protein-coupled receptors known as EDG receptors. Some EDG receptors (e.g., EDG1\; MIM 601974) are S1P receptors\; others (e.g., EDG2\; MIM 602282) are LPA receptors.[supplied by OMIM, Mar 2008].

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Featured Sphingosine-1-Phosphate Receptor 5 Categories

Sphingosine-1-Phosphate Receptor 5 Antibodies

High quality antibodies with extensive validation data.

Sphingosine-1-Phosphate Receptor 5 ELISA Kits

Reliable ELISA kits for a wide range of species.

Sphingosine-1-Phosphate Receptor 5 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Sphingosine-1-Phosphate Receptor 5 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Application ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC
Validations
  • (3)
Cat. No. ABIN1387928
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Human, Monkey, Mouse, Opossum, Rat
Application WB, IHC, IHC (p)
Validations
  • (3)
Cat. No. ABIN207763
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (2)
Cat. No. ABIN7170577
Quantity 100 μg
Datasheet Datasheet

Recommended Sphingosine-1-Phosphate Receptor 5 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6970411
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6970410
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6970409
Quantity 96 tests
Datasheet Datasheet

Recommended Sphingosine-1-Phosphate Receptor 5 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1319097
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3118048
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3136810
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our Sphingosine-1-Phosphate Receptor 5 products

Bock, Pfalzgraff, Weindl: "Sphingosine 1-phospate differentially modulates maturation and function of human Langerhans-like cells." in: Journal of dermatological science, Vol. 82, Issue 1, pp. 9-17, (2016) (PubMed).

Wünsche, Koch, Goldschmeding, Schwalm, Meyer Zu Heringdorf, Huwiler, Pfeilschifter: "Transforming growth factor β2 (TGF-β2)-induced connective tissue growth factor (CTGF) expression requires sphingosine 1-phosphate receptor 5 (S1P5) in human mesangial cells." in: Biochimica et biophysica acta, Vol. 1851, Issue 5, pp. 519-26, (2015) (PubMed).

Brana, Frossard, Pescini Gobert, Martinier, Boschert, Seabrook: "Immunohistochemical detection of sphingosine-1-phosphate receptor 1 and 5 in human multiple sclerosis lesions." in: Neuropathology and applied neurobiology, Vol. 40, Issue 5, pp. 564-78, (2014) (PubMed).

van Doorn, Lopes Pinheiro, Kooij, Lakeman, van het Hof, van der Pol, Geerts, van Horssen, van der Valk, van der Kam, Ronken, Reijerkerk, de Vries: "Sphingosine 1-phosphate receptor 5 mediates the immune quiescence of the human brain endothelial barrier." in: Journal of neuroinflammation, Vol. 9, pp. 133, (2012) (PubMed).

Strochlic, Dwivedy, van Horck, Falk, Holt: "A role for S1P signalling in axon guidance in the Xenopus visual system." in: Development (Cambridge, England), Vol. 135, Issue 2, pp. 333-42, (2007) (PubMed).

Niedernberg, Scherer, Busch, Kostenis: "Comparative analysis of human and rat S1P(5) (edg8): differential expression profiles and sensitivities to antagonists." in: Biochemical pharmacology, Vol. 64, Issue 8, pp. 1243-50, (2002) (PubMed).

Im, Clemens, Macdonald, Lynch: "Characterization of the human and mouse sphingosine 1-phosphate receptor, S1P5 (Edg-8): structure-activity relationship of sphingosine1-phosphate receptors." in: Biochemistry, Vol. 40, Issue 46, pp. 14053-60, (2001) (PubMed).

Im, Heise, Ancellin, ODowd, Shei, Heavens, Rigby, Hla, Mandala, McAllister, George, Lynch: "Characterization of a novel sphingosine 1-phosphate receptor, Edg-8." in: The Journal of biological chemistry, Vol. 275, Issue 19, pp. 14281-6, (2000) (PubMed).

Mannioui, Vauzanges, Fini, Henriet, Sekizar, Azoyan, Thomas, Pasquier, Giovannangeli, Demeneix, Lubetzki, Zalc: "The Xenopus tadpole: An in vivo model to screen drugs favoring remyelination." in: Multiple sclerosis (Houndmills, Basingstoke, England), pp. 1352458517721355 (PubMed).

Synonyms and alternative names related to Sphingosine-1-Phosphate Receptor 5

sphingosine-1-phosphate receptor 5 (S1PR5), sphingosine-1-phosphate receptor 5a (s1pr5a), sphingosine-1-phosphate receptor 5 (s1pr5), sphingosine-1-phosphate receptor 5 (S1pr5), sphingosine-1-phosphate receptor 5b (s1pr5b), Edg-8, edg-8, EDG8, edg8, Edg8, fd11a07, lpB4, S1P5, s1p5, SPPR-1, sppr-1, SPPR-2, sppr-2, wu:fd11a07, xts1p5, zgc:92296, zgc:158362

Protein level used designations for Sphingosine-1-Phosphate Receptor 5

  • S1P receptor 5
  • S1P receptor Edg-8
  • endothelial differentiation G-protein-coupled receptor 8
  • endothelial differentiation, sphingolipid G-protein-coupled receptor, 8
  • sphingosine 1-phosphate receptor 5
  • sphingosine 1-phosphate receptor EDG8
  • sphingosine 1-phosphate receptor Edg-8
  • sphingosine-1-phosphate receptor 1
  • NRG-1
  • S1P5
  • nerve growth factor-regulated G-protein-coupled receptor 1
  • lysophospholipid receptor B4
  • sphingosine-1-phosphate receptor LPB4
  • Sphingosine 1-phosphate receptor Edg-8
  • endothelial differentiation, sphingolipid G-protein-coupled receptor 8
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