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Data indicate that miR (show MLXIP Proteins)-206's effect on Myc (show MYC Proteins) was mediated through MAP3K13.
LZK cooperates with DLK (show DAPK3 Proteins) to promote retinal ganglion cell death in response to axon injury.
Chromosomal localization studies involving FISH mapping demonstrated that the human LZK gene is located at 3q27.
Scaffold protein (show HOMER1 Proteins) POSH (show SH3RF1 Proteins), in association with Shroom3 and mixed lineage kinase LZK, relays axon outgrowth inhibition downstream of NogoA (show RTN4 Proteins) and PirB (show LILRB3 Proteins) proteins.
The protein encoded by this gene is a member of serine/threonine protein kinase family. This kinase contains a dual leucine-zipper motif, and has been shown to form dimers/oligomers through its leucine-zipper motif. This kinase can phosphorylate and activate MAPK8/JNK, MAP2K7/MKK7, which suggests a role in the JNK signaling pathway.
leucine zipper-bearing kinase
, mitogen-activated protein kinase kinase kinase 13
, mitogen activated protein kinase kinase kinase 13 type A
, mitogen-activated protein kinase kinase kinase 13-A
, mixed lineage kinase
, mitogen activated protein kinase kinase kinase 13