anti-Cow (Bovine) Mediator Complex Subunit 6 antibody for Immunohistochemistry

Recommended Mediator Complex Subunit 6 Antibody (supplied by: Log in to see )

Antigen
Mediator Complex Subunit 6 (MED6) Antibodies
  • NY-REN-28
  • wu:fa14c11
  • zgc:86933
  • 1500012F11Rik
  • AU019660
  • AV213303
  • RNA polymerase transcriptional regulation mediator-like protein
  • mediator complex subunit 6
  • hypothetical protein
  • MED6
  • Med6
  • med6
  • CAALFM_C306170CA
Epitope
C-Term
14
10
10
10
8
8
8
7
3
1
1
1
1
1
1
1
Reactivity
Cow (Bovine), Dog (Canine), Horse (Equine), Human, Mouse (Murine), Rabbit, Rat (Rattus)
78
19
17
6
5
5
4
4
4
3
1
1
1
1
1
Host
Rabbit
67
12
Clonality
Polyclonal
Conjugate
Un-conjugated
4
4
4
4
4
4
Application
Immunohistochemistry (IHC), Western Blotting (WB)
79
43
3
2
2
2
Options
Supplier
Log in to see
Supplier Product No.
Log in to see

Available images

Catalog No. ABIN2780688
$ 289.00
Plus shipping costs $45.00

General

Antigen Mediator Complex Subunit 6 (MED6) Antibodies
Epitope C-Term
(14), (10), (10), (10), (8), (8), (8), (7), (3), (1), (1), (1), (1), (1), (1), (1)
Reactivity Cow (Bovine), Dog (Canine), Horse (Equine), Human, Mouse (Murine), Rabbit, Rat (Rattus)
(78), (19), (17), (6), (5), (5), (4), (4), (4), (3), (1), (1), (1), (1), (1)
Host Rabbit
(67), (12)
Clonality
Polyclonal
Conjugate Un-conjugated
(4), (4), (4), (4), (4), (4)
Application Immunohistochemistry (IHC), Western Blotting (WB)
(79), (43), (3), (2), (2), (2)
Supplier Log in to see

Product details

Target Details Application Details Handling Images
Blocking Peptide Blocking peptide for this product available: ABIN2182523
Sequence KPGEKPVPVD QTKKEAEPIP ETVKPEEKET TKNVQQTVSA KGPPEKRMRL
Predicted Reactivity Cow: 79%, Dog: 86%, Horse: 93%, Human: 100%, Mouse: 79%, Rabbit: 93%, Rat: 86%
Characteristics This is a rabbit polyclonal antibody against MED6. It was validated on Western Blot.
Purification Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the C-terminal region of Human MED6

Target Details

Product details Application Details Handling Images back to top
Antigen
Alternative Name MED6 (MED6 Antibody Abstract)
Background MED6 is a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. And mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Alias Symbols: NY-REN-28
Protein Interaction Partner: TARDBP, UBC, CDK19, CDK8, MED10, MED23, CCNC, MED19, MED26, FBXW7, MED11, MED28, MED29, MED4, MED12, MED7, MED21, MED1, SMARCA4, BCL6, SUZ12, CUL1, SKP1, CTDP1, MED25, SREBF1, MED15, VDR, OBFC1, MED18, ZC3H13, TADA2A, RARA, PARP1, SMAD3, SMAD2, SMAD1, MED
Protein Size: 246
Molecular Weight 28 kDa
Gene ID 10001
NCBI Accession NM_005466, NP_005457
UniProt O75586
Pathways Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha

Application Details

Product details Target Details Handling Images back to top
Restrictions For Research Use only

Handling

Product details Target Details Application Details Images back to top
Format Liquid
Concentration 1 mg/mL
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeat freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Images

Product details Target Details Application Details Handling back to top
Supplier Images
Western Blotting (WB) image for anti-Mediator Complex Subunit 6 (MED6) (C-Term) antibody (ABIN2780688) Host: Rabbit Target Name: MED6 Sample Type: Lung Tumor lysates Antibody Dilutio...
Immunohistochemistry (IHC) image for anti-Mediator Complex Subunit 6 (MED6) (C-Term) antibody (ABIN2780688) Rabbit Anti-MED6 Antibody Paraffin Embedded Tissue: Human Lung cell Cellula...