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Human Monoclonal MTF2 Primary Antibody for WB - ABIN2668833
Li, Isono, Yamada, Endo, Endoh, Shinga, Mizutani-Koseki, Otte, Casanova, Kitamura, Kamijo, Sharif, Ohara, Toyada, Bernstein, Brockdorff, Koseki: Mammalian polycomb-like Pcl2/Mtf2 is a novel regulatory component of PRC2 that can differentially modulate polycomb activity both at the Hox gene cluster and at Cdkn2a genes. in Molecular and cellular biology 2010
the F61L/S86F mutant of MTF2 Tudor-PHD1 (show EGLN2 Antibodies) was able to bind to H3K36me3 as strong as the PHF1 (show PHF1 Antibodies) Tudor bound to this PTM . We concluded that the hydrophobic patch plays an essential role in binding of these Tudors to methylated chromatin
these studies identify JARID2 (show JARID2 Antibodies), MTF2, and esPRC2p48 as important regulatory subunits of PRC2 in ES cells and reveal critical functions of these subunits
Data show that Pcl2 differentially regulates Polycomb-mediated repression of Hox and Cdkn2a genes.
Binds to the metal-regulating-element (MRE) of metallothionein-1A gene promoter. Binding is zinc-dependent.
metal-response element-binding transcription factor 2
, polycomblike 2
, metal response element binding transcription factor 2
, metal response element binding transcription factor 2 a
, metal response element-binding transcription factor 2
, metal regulatory transcription factor 2
, metal-response element-binding transcription factor 2-like
, metal-response element DNA-binding protein M96
, polycomb-like 2
, polycomb-like protein 2
, putative DNA binding protein
, tudor domain containing 19A
, metal response element DNA-binding protein M96
, zinc-regulated factor 1