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|Antigen||Bone Morphogenetic Protein 7 (BMP7) Antibodies|
|Conjugate||This BMP7 antibody is un-conjugated Alternatives|
Blocking Antibody (Inhibition), ELISA, Western Blotting (WB)
|Supplier||Log in to see|
Product Details anti-BMP7 AntibodyTarget Details BMP7 Application Details Handling Images
|Purification||Protein A affinity chromatography|
|Immunogen||BMP7 antibody was raised in mouse using recombinant human BMP-7/OP-1 as the immunogen.|
|Plasmids, Primers & others|
Target Details BMP7Product Details anti-BMP7 Antibody Application Details Handling Images back to top
|Alternative Name||BMP7 (BMP7 Antibody Abstract)|
|Background||TGF beta family members are key modulators of cell proliferation, differentiation, matrix synthesis, and apoptosis. As implied by their name, BMPs initiate, promote, and regulate the development, growth and remodeling of bone and cartilage. In addition to this role, BMPs are also involved in prenatal development and postnatal growth, remodeling and maintenance of a variety of other tissues and organs. BMP-7, also known as osteogenic protein-1 or OP-1, is a potent bone inducing agent, which in the presence of appropriate osteoconductive carrier (e.g. collagen sponge or synthetic hydroxyapatite) can be used in the treatment of bone defects. A bone-graft substitute, called OP-1TM implant, made of recombinant human BMP-7 associated with bovine bone-derived collagen, has recently been approved by the FDA as a device for treating critical-size bone fractures. Synonyms: Monoclonal BMP7 antibody, Anti-BMP7 antibody, BMP-7 antibody, Bone Morphogenetic antibody, 7 antibody,OP-1 antibody.|
|Molecular Weight||28.8 kDa (predicted detection band MW)|
|Pathways||Steroid Hormone Mediated Signaling Pathway, Stem Cell Maintenance|
Application DetailsProduct Details anti-BMP7 Antibody Target Details BMP7 Handling Images back to top
ELISA: 2-4 µg/mL
Optimal conditions should be determined by the investigator.
|Restrictions||For Research Use only|
HandlingProduct Details anti-BMP7 Antibody Target Details BMP7 Application Details Images back to top
|Buffer||Lyophilized from PBS.|
Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.
|Storage Comment||Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.|