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SNP genotyping of an affected proband with primary ciliary dyskinesia reveals homozygous nonsense variant in DNAH8 gene which can be a candidate for disease susceptibility.
Cocaine could inhibit the activities of ATPase, LDH and SDH (show SDS ELISA Kits) in cultured splenocytes.
T complex distorter 2 candidate gene, Dnahc8, encodes at least two testis-specific axonemal dynein heavy chains that differ extensively at their amino and carboxyl termini
The interactions of MAP1B with LIS1 in hippocampal neurons, and the association of LIS1 with dynein are reported.
major isoform of DNAHC8 (show Dnah5 ELISA Kits) is copiously expressed, carries an extended N-terminus and full-length C-terminus, and is stable and equally abundant in both testis and sperm from +/+ and t/t animals
Lis1 does not interact with all dynein complexes found in the brain.
The protein encoded by this gene is a heavy chain of an axonemal dynein involved in sperm and respiratory cilia motility. Axonemal dyneins generate force through hydrolysis of ATP and binding to microtubules.
axonemal beta dynein heavy chain 8
, ciliary dynein heavy chain 8
, dynein heavy chain 8, axonemal
, dynein, axonemal, heavy polypeptide 8
, axonemal dynein heavy chain 8 Dnahc8
, dynein, axon, heavy chain 8
, dynein-like protein 8
, dynein, axonemal, heavy chain 8
, dynein heavy chain 8, axonemal-like