Browse our anti-Dystrobrevin Binding Protein 1 (DTNBP1) Antibodies

Full name:: anti-Dystrobrevin Binding Protein 1 Antibodies (DTNBP1)

On www.antibodies-online.com are 120 Dystrobrevin Binding Protein 1 (DTNBP1) Antibodies from 18 different suppliers available. Additionally we are shipping Dystrobrevin Binding Protein 1 Proteins (16) and Dystrobrevin Binding Protein 1 Kits (9) and many more products for this protein. A total of 154 Dystrobrevin Binding Protein 1 products are currently listed.

Synonyms:: 5430437B18Rik, AW048963, Bloc1s8, CG6856, DBND, Ddysb, Dmel\\CG6856, DTNBP1, dysbindin, HPS7, MGC83903, MGC85477, My031, sdy, zgc:56462

list all antibodies	Gene Name	GeneID	UniProt
	DTNBP1	84062	Q96EV8
	DTNBP1	94245	Q91WZ8
	DTNBP1	641528	Q5M834
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Top referenced anti-Dystrobrevin Binding Protein 1 Antibodies

Human Polyclonal DTNBP1 Primary Antibody for IHC, IHC (p) - ABIN4306530 : Gokhale, Mullin, Zlatic, Easley, Merritt, Raj, Larimore, Gordon, Peden, Sanyal, Faundez: The N-ethylmaleimide-sensitive factor and dysbindin interact to modulate synaptic plasticity. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2015 (PubMed)
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More Antibodies against Dystrobrevin Binding Protein 1 Interaction Partners

Fruit Fly (Drosophila melanogaster) Dystrobrevin Binding Protein 1 (DTNBP1) interaction partners

Dysbindin levels regulate the access to EGTA-sensitive vesicles at the neuromuscular junction.
Results indicate that perturbations downstream of DTNBP1, confer susceptibility to copper, a metal that in excess (show RCC1 Antibodies) is a neurotoxin and whose depletion constitutes a micronutrient deficiency.
Loss-of-function alleles of dysbindin or Blos1 (show BLOC1S1 Antibodies) impaired neurotransmitter release and synaptic function and plasticity.
optimal binding ratio between Dysb and Ebony might contribute to such non-linear effects. Thus, Ddysb-dependent regulation of Ebony could be one of the mechanisms that mediate dopamine signal
study found that dysbindin (CG6856) is required presynaptically for the retrograde, homeostatic modulation of neurotransmission, and functions in a dose-dependent manner downstream or independently of calcium influx

Human Dystrobrevin Binding Protein 1 (DTNBP1) interaction partners

Our results suggest that DTNBP1 and NRN1 (show NRN1 Antibodies) genes show a joint effect on the risk for schizophrenia spectrum disorders. Although the precise mechanism underlying this effect is unclear, the fact that these genes have been involved in synaptic maturation, connectivity and glutamate (show GRIN1 Antibodies) signalling suggests that our findings could be of value as a link to the schizophrenia aetiology.
Study analyzed human-specific dysbindin-1B expression in multiple brain areas in mouse models and showed that dysbindin-1B exerts a dominant-negative effect on the BLOC-1 (show BLOC1S1 Antibodies) complex; this effect may lead to cognitive impairment.
This study demonstrated that BDNF (show BDNF Antibodies) and dysbindin-1 linked to risk for schizophrenia function together to regulate interneuron development and cortical network activity.
This is the first study to suggest that known and newly described polymorphisms in COMT (show COMT Antibodies), BDNF (show BDNF Antibodies), and DTNBP1, genes associated with executive and memory functions in healthy individuals and other clinical populations may modulate cognitive outcome in patients with brain tumors
Data suggest that, in cardiomyocytes, TRIM32 attenuates activation of SRF signaling and hypertrophy due to dysbindin; TRIM24 promotes these effects. TRIM32 promotes dysbindin degradation; TRIM24 protects dysbindin from degradation. (TRIM = tripartite motif-containing protein; SRF = serum response factor)
Authors report the examination of DNA methylation status of DTNBP1 promoter region, one of the most credible candidate genes affected in SCZ.
DTNBP1 is likely to play a role in development of auditory related, visual and olfactory hallucinations
dysbindin-1A protein levels are highly regulated in the nucleus and that dysbindin-1A regulates transcription factor NF-kappa B (show NFKB1 Antibodies) activity to promote the expression of MMP-9 (show MMP9 Antibodies) and TNF-alpha (show TNF Antibodies)
Study demonstrated that dysbindin-1B, rather than dysbindin-1A and dysbindin-1C, has the ability to aggregate
The present findings intransgenic mice expressing human DTNBP1 support the role of dysbindin-1 in psychiatric disorders.

Mouse (Murine) Dystrobrevin Binding Protein 1 (DTNBP1) interaction partners

Nuclear SREBP1 (show SREBF1 Antibodies) is dramatically reduced in dysbindin-1 knockout mice.
loss of DTNBP1 in pyramidal neurons diminished activity-dependent secretion of brain-derived neurotrophic factor (BDNF (show BDNF Antibodies)).
Dysbindin-1 modulates thus D2 and D3 receptor (show DRD3 Antibodies) signaling, supporting a link to schizophrenia
Results indicate that perturbations downstream of DTNBP1, confer susceptibility to copper, a metal that in excess (show RCC1 Antibodies) is a neurotoxin and whose depletion constitutes a micronutrient deficiency.
Results suggest that Dtnbp1 deficiency may lead to increased vulnerability to schizophrenia under environmental conditions where circadian rhythms are altered
Snapin-dysbindin interaction regulates synaptic vesicle positional priming through BLOC-1/AP-3-dependent sorting.
Dysbindin has three isoforms associating with different complexes in the P2 fraction of mouse brain.
Dysbindin-1C deficiency causes impaired autophagy, which is likely implicated in the pathogenesis of schizophrenia.
The neurite outgrowth defect induced by knockdown of DISC1 (show DISC1 Antibodies) was partially reversed by coexpression of dysbindin.
dysbindin-1C, rather than dysbindin-1A, regulates adult hippocampal neurogenesis in a non-cell autonomous manner

Dystrobrevin Binding Protein 1 (DTNBP1) Antigen Profile

Antigen Summary

This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. A similar protein in mouse is a component of a protein complex termed biogenesis of lysosome-related organelles complex 1 (BLOC-1), and binds to alpha- and beta-dystrobrevins, which are components of the dystrophin-associated protein complex (DPC). Mutations in this gene are associated with Hermansky-Pudlak syndrome type 7. This gene may also be associated with schizophrenia. Multiple transcript variants encoding distinct isoforms have been identified for this gene.

Alternative names and synonyms associated with Dystrobrevin Binding Protein 1 (DTNBP1)

dystrobrevin binding protein 1 (DTNBP1) antibody
Dysbindin (Dysb) antibody
Dysbindin (dtbp1) antibody
dystrobrevin binding protein 1a (dtnbp1a) antibody
dystrobrevin binding protein 1 L homeolog (dtnbp1.L) antibody
dystrobrevin binding protein 1 S homeolog (dtnbp1.S) antibody
dystrobrevin binding protein 1 (dtnbp1) antibody
dystrobrevin binding protein 1 (Dtnbp1) antibody

5430437B18Rik antibody
AW048963 antibody
Bloc1s8 antibody
CG6856 antibody
DBND antibody
Ddysb antibody
Dmel\\CG6856 antibody
DTNBP1 antibody
dysbindin antibody
HPS7 antibody
MGC83903 antibody
MGC85477 antibody
My031 antibody
sdy antibody
zgc:56462 antibody

Protein level used designations for DTNBP1

, , , , , , , , , , , , , , , , , , , , dysbindin CG6856-PA CG6856-PB dysb-PA dysb-PB Dysbindin BLOC-1 subunit 8-A biogenesis of lysosome-related organelles complex 1 subunit 8-A dysbindin-A dystrobrevin binding protein 1 dystrobrevin-binding protein 1-A BLOC-1 subunit 8 Hermansky-Pudlak syndrome 7 protein biogenesis of lysosomal organelles complex-1, subunit 8 biogenesis of lysosome-related organelles complex 1 subunit 8 dysbindin-1 HPS7 protein homolog dystrobrevin-binding protein 1 hermansky-Pudlak syndrome 7 protein homolog sandy distrobrevin binding protein 1

GENE ID	SPECIES
100145862	Ovis aries
40052	Drosophila melanogaster
100195576	Salmo salar
394109	Danio rerio
446421	Xenopus laevis
447615	Xenopus laevis
747324	Pan troglodytes
100216117	Xenopus (Silurana) tropicalis
84062	Homo sapiens
94245	Mus musculus
420840	Gallus gallus
100049697	Sus scrofa
506612	Bos taurus
641528	Rattus norvegicus

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Show all anti-Dystrobrevin Binding Protein 1 (DTNBP1) Antibodies with Pubmed References