anti-Rat (Rattus) GRIN1 antibody for Immunofluorescence

Recommended GRIN1 Antibody

Antigen
Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 1 (GRIN1) Antibodies
  • GluN1
  • MRD8
  • NMDA1
  • NMDAR1
  • NR1
  • nmda1
  • nmdar1
  • GB19253
  • GRIN1
  • NMD-R1
  • GluRdelta1
  • GluRzeta1
  • M100174
  • Nmdar
  • Rgsc174
  • NMDAR1.1
  • zgc:152678
  • glutamate ionotropic receptor NMDA type subunit 1
  • glutamate receptor, ionotropic, N-methyl D-aspartate 1 S homeolog
  • NMDA receptor 1
  • glutamate receptor, ionotropic, NMDA1 (zeta 1)
  • glutamate receptor, ionotropic, N-methyl D-aspartate 1a
  • GRIN1
  • grin1.S
  • grin1
  • Grin1
  • Nmdar1
  • grin1a
Reactivity
Human, Mouse (Murine), Rat (Rattus)
285
283
233
15
5
5
5
3
3
3
2
2
1
1
Host
Mouse
279
52
13
Clonality
Monoclonal
Conjugate
This GRIN1 antibody is un-conjugated
13
9
9
9
9
9
9
7
6
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
1
Application
Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
229
149
87
41
36
24
21
14
10
9
2
2
2
1
Options

Available images

Catalog No. ABIN152467
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Clonality References Details
14.593022 ABIN1532466 IF IHC ELISA WB Rabbit IgG AA 856-905 Polyclonal 0
13.551264 ABIN2140947 IF IHC ELISA Rabbit IgG pSer890 Polyclonal 0
13 ABIN6263664 ELISA ICC IF IHC WB Rabbit IgG Polyclonal 0
11.593022 ABIN1531449 IF IHC ELISA Rabbit IgG AA 856-905, pSer890 Polyclonal 0
10 ABIN6256445 ELISA ICC IF IHC WB Rabbit IgG pSer890 Polyclonal 0
8.593022 ABIN6580458 IF Rabbit IgG Polyclonal 0
7 ABIN2888740 ELISA IF IHC IHC (p) WB Rabbit IgG AA 856-905 Polyclonal 0
4.9463387 ABIN5952549 FACS ICC IF IHC IHC (p) WB Rabbit IgG C-Term JM11-26 0
1 ABIN2568395 IF IHC Rabbit IgG pSer890 Polyclonal 0
1 ABIN596802 IF Rabbit IgG Polyclonal 0
1 ABIN2884116 ELISA IF IHC IHC (p) Rabbit IgG pSer890 Polyclonal 0
1 ABIN2891800 IF IHC IHC (p) WB Rabbit Ser885 Polyclonal 0
1 ABIN1578256 IF IHC ELISA Rabbit pSer890 Polyclonal 0
1 ABIN363000 IF Rabbit IgG Polyclonal 1
1 ABIN6582272 ICC IF IHC WB Rabbit pSer890 Polyclonal 0
1 ABIN1578257 IF IHC ELISA WB Rabbit Polyclonal 0
1 ABIN6583102 ICC IF IHC WB Rabbit Polyclonal 0
-2.460639 ABIN5078402 ICC IF IHC WB Mouse IgG1 AA 42-361 S308-48 0
-5.5536613 ABIN251579 ICC IF ELISA WB Goat all Isoforms Polyclonal 2
-13.053661 ABIN6246100 ICC IF IHC Janelia Fluor® 549 Mouse IgG1 AA 42-361, N-Term S308-48 0

General

Antigen Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 1 (GRIN1) Antibodies
Reactivity Human, Mouse (Murine), Rat (Rattus)
(285), (283), (233), (15), (5), (5), (5), (3), (3), (3), (2), (2), (1), (1)
Host Mouse
(279), (52), (13)
Clonality (Clone)
Monoclonal   ( )
Conjugate This GRIN1 antibody is un-conjugated
(13), (9), (9), (9), (9), (9), (9), (7), (6), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1)
Application Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
(229), (149), (87), (41), (36), (24), (21), (14), (10), (9), (2), (2), (2), (1)
Pubmed 13 references available
Supplier

Product Details anti-GRIN1 Antibody

Target Details GRIN1 Application Details Handling References for anti-GRIN1 antibody (ABIN152467) Images
Specificity Specific for the ~120k NR1 subunit of the NMDA receptor.
Purification Tissue culture supernatant
Immunogen Fusion protein containing amino acids 1-564 of the NR1 subunit of rat NMDA receptor.
Clone R1JHL
Isotype IgG
Plasmids, Primers & others

Target Details GRIN1

Product Details anti-GRIN1 Antibody Application Details Handling References for anti-GRIN1 antibody (ABIN152467) Images back to top
Antigen
Alternative Name NMDAR1 (GRIN1 Antibody Abstract)
Background Gene Symbol: GRIN1
Molecular Weight Theoretical MW: 120 kDa
Gene ID 2902
UniProt P35439
Pathways Synaptic Membrane, Feeding Behaviour, Regulation of long-term Neuronal Synaptic Plasticity

Application Details

Product Details anti-GRIN1 Antibody Target Details GRIN1 Handling References for anti-GRIN1 antibody (ABIN152467) Images back to top
Application Notes Western Blot 1:1000, Immunocytochemistry/Immunofluorescence, Immunoprecipitation 3 μg/200 μg lysate, Immunohistochemistry-Paraffin, Immunohistochemistry-FrozenUse in Immunocytochemistry/immunofluorescence and Immunohistochemistry-Frozen reported in scientific literature (PMID: 20414717). Use in Immunohistochemistry-Paraffin reported in scientific literature (PMID 26635527). The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Comment

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Restrictions For Research Use only

Handling

Product Details anti-GRIN1 Antibody Target Details GRIN1 Application Details References for anti-GRIN1 antibody (ABIN152467) Images back to top
Format Lyophilized
Reconstitution Reconstitute with 50 μL PBS to desired concentration.
Buffer Culture supernatant
Buffer contains: No Preservative
Preservative Without preservative
Handling Advice Avoid freeze-thaw cycles
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze-thaw cycles.

References for anti-GRIN1 antibody (ABIN152467)

Product Details anti-GRIN1 Antibody Target Details GRIN1 Application Details Handling Images back to top
Product cited in:

Stewart, Lau, Banks, Bains, Castroflorio, Oliver, Dixon, Kruer, Kullmann, Acevedo-Arozena, Wells, Corrochano, Nolan: "Loss of Frrs1l disrupts synaptic AMPA receptor function, and results in neurodevelopmental, motor, cognitive and electrographical abnormalities." in: Disease models & mechanisms, Vol. 12, Issue 2, 2019 Method employed by authors: Western Blotting (WB) (Sample species: Mouse (Murine)).

Shi, Hung, Rocha, Lin, Linares, Staats, Seah, Wang, Chickering, Lai, Sugawara, Sagare, Zlokovic, Ichida: "Identification and therapeutic rescue of autophagosome and glutamate receptor defects in C9ORF72 and sporadic ALS neurons." in: JCI insight, Vol. 5, 2019 Method employed by authors: Western Blotting (WB) (Sample species: Human).

Shi, Lin, Staats, Li, Chang, Hung, Hendricks, Linares, Wang, Son, Wen, Kisler, Wilkinson, Menendez, Sugawara, Woolwine, Huang, Cowan, Ge, Koutsodendris, Sandor, Komberg, Vangoor, Senthilkumar, Hennes et al.: "Haploinsufficiency leads to neurodegeneration in C9ORF72 ALS/FTD human induced motor neurons. ..." in: Nature medicine, Vol. 24, Issue 3, pp. 313-325, 2018

Gorska-Ponikowska, Perricone, Kuban-Jankowska, Lo Bosco, Barone: "2-methoxyestradiol impacts on amino acids-mediated metabolic reprogramming in osteosarcoma cells by its interaction with NMDA receptor." in: Journal of cellular physiology, 2017 Method employed by authors: Western Blotting (WB) (Sample species: Human).

Hewett, Shi, Gong, Dhandapani, Pilbeam, Hewett et al.: "Spontaneous Glutamatergic Synaptic Activity Regulates Constitutive COX-2 Expression in Neurons: OPPOSING ROLES FOR THE TRANSCRIPTION FACTORS CREB (cAMP RESPONSE ELEMENT BINDING) PROTEIN AND Sp1 ..." in: The Journal of biological chemistry, Vol. 291, Issue 53, pp. 27279-27288, 2016 Method employed by authors: Western Blotting (WB) (Sample species: Rat (Rattus)).

Brai, Marathe, Astori, Fredj, Perry, Lamy, Scotti, Alberi: "Notch1 Regulates Hippocampal Plasticity Through Interaction with the Reelin Pathway, Glutamatergic Transmission and CREB Signaling." in: Frontiers in cellular neuroscience, Vol. 9, pp. 447, 2015 (Sample species: Mouse (Murine)). Further details: Immunohistochemistry (Paraffin-embedded Sections)

Plaza-Zabala, Li, Milovanovic, Loweth, Maldonado, Berrendero, Wolf: "An investigation of interactions between hypocretin/orexin signaling and glutamate receptor surface expression in the rat nucleus accumbens under basal conditions and after cocaine exposure." in: Neuroscience letters, Vol. 557 Pt B, pp. 101-6, 2013 (Sample species: Rat (Rattus)). Further details: Western Blotting

Ferrario, Loweth, Milovanovic, Wang, Wolf: "Distribution of AMPA receptor subunits and TARPs in synaptic and extrasynaptic membranes of the adult rat nucleus accumbens." in: Neuroscience letters, Vol. 490, Issue 3, pp. 180-4, 2011 (Sample species: Rat (Rattus)). Further details: Western Blotting

Tao, Chen, Huang: "Dextromethorphan attenuated the higher vulnerability to inflammatory thermal hyperalgesia caused by prenatal morphine exposure in rat offspring." in: Journal of biomedical science, Vol. 18, pp. 64, 2011 (Sample species: Rat (Rattus)). Further details: Western Blotting

Mashkina, Cizkova, Vanicky, Boldyrev: "NMDA receptors are expressed in lymphocytes activated both in vitro and in vivo." in: Cellular and molecular neurobiology, Vol. 30, Issue 6, pp. 901-7, 2010 Further details: Immunocytochemistry,Immunofluorescence,Immunohistochemistry (Frozen Sections)

Garraway, Xu, Inturrisi: "siRNA-mediated knockdown of the NR1 subunit gene of the NMDA receptor attenuates formalin-induced pain behaviors in adult rats." in: The journal of pain : official journal of the American Pain Society, Vol. 10, Issue 4, pp. 380-90, 2009 (Sample species: Rat (Rattus)).

Lim, Wang, Zeng, Sung, Yang, Mao: "Expression of spinal NMDA receptor and PKCgamma after chronic morphine is regulated by spinal glucocorticoid receptor." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 25, Issue 48, pp. 11145-54, 2005 (Sample species: Rat (Rattus)). Further details: Immunocytochemistry,Western Blotting,Immunofluorescence

Nagy, Kolok, Dezso, Boros, Szombathelyi: "Differential alterations in the expression of NMDA receptor subunits following chronic ethanol treatment in primary cultures of rat cortical and hippocampal neurones." in: Neurochemistry international, Vol. 42, Issue 1, pp. 35-43, 2002

Images

Product Details anti-GRIN1 Antibody Target Details GRIN1 Application Details Handling References for anti-GRIN1 antibody (ABIN152467) back to top
Supplier Images
Western Blotting (WB) image for anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 1 (GRIN1) antibody (ABIN152467) Detection of 120 kDa NMDA NR1 protein in rat brain lysate using ABIN152467.
Western Blotting (WB) image for anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 1 (GRIN1) antibody (ABIN152467) Western Blot: NMDAR1 Antibody (R1JHL) [ABIN152467]
Immunofluorescence (IF) image for anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 1 (GRIN1) antibody (ABIN152467) Immunofluorescence: NMDAR1 Antibody (R1JHL) [ABIN152467] - Mouse neuron stained with ...
Immunocytochemistry (ICC) image for anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 1 (GRIN1) antibody (ABIN152467) Immunocytochemistry: NMDAR1 Antibody (R1JHL) - NR1 surface staining of mouse corical...
Immunocytochemistry (ICC) image for anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 1 (GRIN1) antibody (ABIN152467) Immunocytochemistry: NMDAR1 Antibody (R1JHL) - Mixed rat cortical cultures (21 DIV) ...