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SALM4 cis-interacts with SALM3, inhibits trans-synaptic SALM3 interaction with presynaptic LAR family receptor tyrosine phosphatases and suppresses SALM3-dependent presynaptic differentiation.
Data show that the C-terminal PDZ binding domains of synaptic adhesion-like molecules (SALMs)1-3 are required for neurite outgrowth, and that the N-termini of SALMs 2 and 4 are alsoinvolved in neurite outgrowth.
Cell adhesion molecule that mediates homophilic cell- cell adhesion in a Ca(2+)-independent manner. Promotes neurite outgrowth in hippocampal neurons (By similarity).
leucine rich repeat and fibronectin type III domain containing 3
, leucine-rich repeat and fibronectin type-III domain-containing protein 3-like
, fibronectin type III, immunoglobulin and leucine rich repeat domains 1
, leucine-rich repeat and fibronectin type-III domain-containing protein 3
, synaptic adhesion-like molecule 4
, Leucine-rich repeat and fibronectin type-III domain-containing protein 3
, Synaptic adhesion-like molecule 4