anti-Horse (Equine) NMDAR2A antibody for Western Blotting

Recommended NMDAR2A Antibody

Antigen
Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A) Antibodies
  • NMDAR2A
  • nr2a
  • GRIN2A
  • EPND
  • GluN2A
  • NR2A
  • glutamate ionotropic receptor NMDA type subunit 2A
  • glutamate receptor, ionotropic, N-methyl D-aspartate 2A L homeolog
  • glutamate receptor ionotropic, NMDA 2A
  • glutamate receptor, ionotropic, NMDA2A (epsilon 1)
  • GRIN2A
  • grin2a.L
  • LOC100438553
  • Grin2a
Epitope
Middle Region
118
57
27
19
17
15
10
9
8
8
8
8
7
5
4
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Reactivity
Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rat (Rattus)
270
218
217
6
3
3
1
1
1
1
1
Host
Rabbit
199
137
1
Clonality
Polyclonal
Conjugate
This NMDAR2A antibody is un-conjugated
21
17
15
12
10
10
8
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
4
2
2
2
2
2
2
2
2
2
2
2
2
2
2
Application
Immunohistochemistry (IHC), Western Blotting (WB)
265
205
76
67
59
43
33
26
20
18
3
3
2
2
Options

Available images

Catalog No. ABIN2776120
$ 289.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Clonality References Details
4 ABIN6742541 WB Rabbit AA 1115-1164 Polyclonal 0

General

Antigen Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A) Antibodies
Epitope Middle Region
(118), (57), (27), (19), (17), (15), (10), (9), (8), (8), (8), (8), (7), (5), (4), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rat (Rattus)
(270), (218), (217), (6), (3), (3), (1), (1), (1), (1), (1)
Host Rabbit
(199), (137), (1)
Clonality
Polyclonal
Conjugate This NMDAR2A antibody is un-conjugated
(21), (17), (15), (12), (10), (10), (8), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application Immunohistochemistry (IHC), Western Blotting (WB)
(265), (205), (76), (67), (59), (43), (33), (26), (20), (18), (3), (3), (2), (2)
Pubmed 1 reference available
Supplier

Product Details anti-NMDAR2A Antibody

Target Details NMDAR2A Application Details Handling References for anti-NMDAR2A antibody (ABIN2776120) Images
Blocking Peptide Blocking peptide for this product available: ABIN977683
Sequence DKIYTIDGEK EPGFHLDPPQ FVENVTLPEN VDFPDPYQDP SENFRKGDST
Predicted Reactivity Cow: 77%, Dog: 93%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Mouse: 79%, Rat: 79%
Characteristics This is a rabbit polyclonal antibody against GRIN2A. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human GRIN2A
Plasmids, Primers & others

Target Details NMDAR2A

Product Details anti-NMDAR2A Antibody Application Details Handling References for anti-NMDAR2A antibody (ABIN2776120) Images back to top
Antigen
Alternative Name GRIN2A (GRIN2A Antibody Abstract)
Background N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate-gated ion channels. These receptors have been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C) and NMDAR2D (GRIN2D).N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C), and NMDAR2D (GRIN2D). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: NMDAR2A, NR2A, EPND, GluN2A
Protein Interaction Partner: Nedd4, SPTAN1, DLG4, DLG1, UBC, GRIN1, ARHGAP32, CAMK2B, GRIN3B, GRIN3A, DLGAP1, CAMK2A, DLG2, AP1M1, INADL, IL16, AP4M1, RGS3, PTK2B, DLG3, CASK, SRC, PRKCA, PTPN4, PLCG1, GRIN2A, FYN, CDK5, ACTN1, Dlgap2,
Protein Size: 1464
Molecular Weight 163 kDa
Gene ID 2903
NCBI Accession NM_000833, NP_000824
UniProt Q12879
Pathways Synaptic Membrane, Regulation of long-term Neuronal Synaptic Plasticity

Application Details

Product Details anti-NMDAR2A Antibody Target Details NMDAR2A Handling References for anti-NMDAR2A antibody (ABIN2776120) Images back to top
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 1464 AA

Restrictions For Research Use only

Handling

Product Details anti-NMDAR2A Antibody Target Details NMDAR2A Application Details References for anti-NMDAR2A antibody (ABIN2776120) Images back to top
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-NMDAR2A antibody (ABIN2776120)

Product Details anti-NMDAR2A Antibody Target Details NMDAR2A Application Details Handling Images back to top
Background publications

Kim, Chang, Nagpal, Yamashita, Baek, Dasgupta, Wu, Osada, Woo, Westra, Trink, Ratovitski, Moon, Sidransky: "The N-methyl-D-aspartate receptor type 2A is frequently methylated in human colorectal carcinoma and suppresses cell growth." in: Oncogene, Vol. 27, Issue 14, pp. 2045-54, 2008

Images

Product Details anti-NMDAR2A Antibody Target Details NMDAR2A Application Details Handling References for anti-NMDAR2A antibody (ABIN2776120) back to top
Supplier Images
Western Blotting (WB) image for anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A) (Middle Region) antibody (ABIN2776120) WB Suggested Anti-GRIN2A Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:62500 Pos...
Immunohistochemistry (IHC) image for anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A) (Middle Region) antibody (ABIN2776120) Sample Type : Rat Hippocampal Neurons - 14DIV Primary Antibody Dilution : 1:200 S...