anti-Rat (Rattus) NMDAR2A antibody for Immunohistochemistry

Recommended NMDAR2A Antibody (supplied by: Log in to see )

Antigen
Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A) Antibodies
  • NMDAR2A
  • nr2a
  • GRIN2A
  • EPND
  • GluN2A
  • NR2A
  • glutamate ionotropic receptor NMDA type subunit 2A
  • glutamate receptor, ionotropic, N-methyl D-aspartate 2A L homeolog
  • glutamate receptor ionotropic, NMDA 2A
  • glutamate receptor, ionotropic, NMDA2A (epsilon 1)
  • GRIN2A
  • grin2a.L
  • LOC100438553
  • Grin2a
Epitope
N-Term
87
28
28
19
15
11
10
10
8
8
7
5
3
3
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Rat (Rattus)
212
173
173
7
4
3
2
2
1
1
1
Host
Rabbit
173
106
1
Clonality
Polyclonal
Conjugate
This NMDAR2A antibody is un-conjugated
16
16
14
11
9
9
7
5
5
5
5
5
5
5
5
5
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
Application
Immunohistochemistry (IHC), Western Blotting (WB)
236
176
63
60
53
34
26
26
21
16
3
3
2
1
Options
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Available images

Catalog No. ABIN361397
$ 508.20
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
22.280954 ABIN361396 IHC IP WB Rabbit C-Term Log in to see Polyclonal 0
19.280954 ABIN2483869 ICC IF IHC WB Atto 390 Mouse IgG2a AA 75-325 Log in to see S327-95 1
19.280954 ABIN2483870 ICC IF IHC WB Atto 488 Mouse IgG2a AA 75-325 Log in to see S327-95 1
19.280954 ABIN2483871 ICC IF IHC WB Atto 565 Mouse IgG2a AA 75-325 Log in to see S327-95 1
19.280954 ABIN2483872 ICC IF IHC WB Atto 594 Mouse IgG2a AA 75-325 Log in to see S327-95 1
19.280954 ABIN2483873 ICC IF IHC WB Atto 633 Mouse IgG2a AA 75-325 Log in to see S327-95 1
19.280954 ABIN2483874 ICC IF IHC WB Atto 655 Mouse IgG2a AA 75-325 Log in to see S327-95 1
19.280954 ABIN2483875 ICC IF IHC WB Atto 680 Mouse IgG2a AA 75-325 Log in to see S327-95 1
19.280954 ABIN2483876 ICC IF IHC WB Atto 700 Mouse IgG2a AA 75-325 Log in to see S327-95 1
19.280954 ABIN2483878 ICC IF IHC WB APC Mouse IgG2a AA 75-325 Log in to see S327-95 1
19.280954 ABIN2483880 ICC IF IHC WB FITC Mouse IgG2a AA 75-325 Log in to see S327-95 1
19.280954 ABIN2483882 ICC IF IHC WB PE-Atto 594 Mouse IgG2a AA 75-325 Log in to see S327-95 1
19.280954 ABIN2483883 ICC IF IHC WB PerCP Mouse IgG2a AA 75-325 Log in to see S327-95 1
19.280954 ABIN2483892 ICC IF IHC WB Atto 680 Mouse IgG2b AA 75-325 Log in to see S327A-38 1
19.280954 ABIN2483895 ICC IF IHC WB APC Mouse IgG2b AA 75-325 Log in to see S327A-38 1
19.280954 ABIN2483886 ICC IF IHC WB Atto 390 Mouse IgG2b AA 75-325 Log in to see S327A-38 1
19.280954 ABIN2483887 ICC IF IHC WB Atto 488 Mouse IgG2b AA 75-325 Log in to see S327A-38 1
19.280954 ABIN2483888 ICC IF IHC WB Atto 565 Mouse IgG2b AA 75-325 Log in to see S327A-38 1
19.280954 ABIN2483889 ICC IF IHC WB Atto 594 Mouse IgG2b AA 75-325 Log in to see S327A-38 1
19.280954 ABIN2483891 ICC IF IHC WB Atto 655 Mouse IgG2b AA 75-325 Log in to see S327A-38 1

General

Antigen Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A) Antibodies
Epitope N-Term
(87), (28), (28), (19), (15), (11), (10), (10), (8), (8), (7), (5), (3), (3), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Rat (Rattus)
(212), (173), (173), (7), (4), (3), (2), (2), (1), (1), (1)
Host Rabbit
(173), (106), (1)
Clonality
Polyclonal
Conjugate This NMDAR2A antibody is un-conjugated
(16), (16), (14), (11), (9), (9), (7), (5), (5), (5), (5), (5), (5), (5), (5), (5), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application Immunohistochemistry (IHC), Western Blotting (WB)
(236), (176), (63), (60), (53), (34), (26), (26), (21), (16), (3), (3), (2), (1)
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Product Details anti-NMDAR2A Antibody

Target Details NMDAR2A Application Details Handling Images
Specificity Specific for the ~180k NR2A subunit of the NMDA receptor.
Cross-Reactivity Rat (Rattus)
Predicted Reactivity bovine, canine, mouse
Purification Antigen Affinity Purified from Pooled Serum
Immunogen Synthetic peptide corresponding to amino acid residues from the N-terminal region of the NR2A subunit conjugated to KLH
Plasmids, Primers & others

Target Details NMDAR2A

Product Details anti-NMDAR2A Antibody Application Details Handling Images back to top
Antigen
Alternative Name GRIN2A (GRIN2A Antibody Abstract)
Background The ion channels activated by glutamate are typically divided into two classes. Glutamate receptors that are activated by kainate and a-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid (AMPA) are known as kainate/AMPA receptors (K/AMPAR). Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR). The NMDAR plays an essential role in memory, neuronal development and it has also been implicated in several disorders of the central nervous system including Alzheimer’s, epilepsy and ischemic neuronal cell death (Grosshans et al., 2002, Wenthold et al., 2003, Carroll and Zukin, 2002). The NMDA receptor is also one of the principal molecular targets for alcohol in the CNS (Lovinger et al., 1989, Alvestad et al., 2003, Snell et al., 1996). The NMDAR is also potentiated by protein phosphorylation (Lu et al., 1999). The rat NMDAR1 (NR1) was the first subunit of the NMDAR to be cloned. The NR1 protein can form NMDA activated channels when expressed in Xenopus oocytes but the currents in such channels are much smaller than those seen in situ. Channels with more physiological characteristics are produced when the NR1 subunit is combined with one or more of the NMDAR2 (NR2 A-D) subunits. Anti-NMDA Receptor, NR2A Subunit Western blot of 10 ug of rat hippocampal lysate showing specific immunolabeling of the ~180k NR2A subunit of the NMDA receptor.
Molecular Weight '180 kDa
Gene ID 24409
UniProt Q00959
Pathways Synaptic Membrane, Regulation of long-term Neuronal Synaptic Plasticity

Application Details

Product Details anti-NMDAR2A Antibody Target Details NMDAR2A Handling Images back to top
Application Notes Recommended Dilution: WB: 1:1000 IHC: 1:500 Quality Control: Western blots performed on each lot.
Restrictions For Research Use only

Handling

Product Details anti-NMDAR2A Antibody Target Details NMDAR2A Application Details Images back to top
Format Liquid
Buffer 100 μL in 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.
Storage -20 °C

Images

Product Details anti-NMDAR2A Antibody Target Details NMDAR2A Application Details Handling back to top
Supplier Images
Western Blotting (WB) image for anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A) (N-Term) antibody (ABIN361397) Western blots of 10 ug of rat hippocampal lysate showing specific immunolabeling of t...
Western Blotting (WB) image for anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A) (N-Term) antibody (ABIN361397) Western blot of 10 µg of rat hippocampal lysate showing specific immunolabeling of th...
Immunostaining (ISt) image for anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A) (N-Term) antibody (ABIN361397) Immunostaining of 21 DIV nucleofected mouse striatal neuron (green) co-cultured with ...