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|Antigen||Neurexin 1 (NRXN1) Antibodies|
ELISA, Flow Cytometry (FACS), Western Blotting (WB)
|1 reference available|
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|Blocking Peptide||Blocking peptide for this product available: ABIN369260|
|Specificity||This antibody is expected to recognise all reported isoforms.|
|Predicted Reactivity||Human, Mouse, Rat, Dog|
|Purification||Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.|
|Immunogen||Peptide with sequence C-KEKQPSSAKSSNKN, from the C Terminus of the protein sequence according to NP_004792.1 , NP_620072.1.|
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|Alternative Name||NRXN1 (NRXN1 Antibody Abstract)|
|Background||Neurexin 1, DKFZp313P2036, NRXN1, FLJ35941, Hs.22998, KIAA0578, neurexin I|
|NCBI Accession||NP_004792, NP_620072|
|Pathways||Synaptic Membrane, Skeletal Muscle Fiber Development|
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DS WB Results: In transfected HEK293 transiently expressing full-length Human NRXN1 (myc and DYKDDDDK tagged), bands of approx. 75 and 60 kDa were observed. No bands were observed in mock-transfected HEK293 and the same band was observed using anti-DYKDDDDK tag antibody. Recommended concentration: 0.5-1 μg/mL. Primary incubations were for 1 hour.
Peptide ELISA Statement: Peptide ELISA: antibody detection limit dilution 1:128000.
Flow Cytometry: Flow cytometric analysis of Kelly cells. Recommended concentration: 10ug/ml.
|Restrictions||For Research Use only|
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|Buffer||Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.|
|Precaution of Use||This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||Minimize freezing and thawing.|
|Storage Comment||Aliquot and store at -20 °C.|
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Feng, Schroer, Yan, Song, Yang, Bockholt, Cook, Skinner, Schwartz, Sommer: "High frequency of neurexin 1beta signal peptide structural variants in patients with autism." in: Neuroscience letters, Vol. 409, Issue 1, pp. 10-3, 2006
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