anti-Human Neurexin 1 antibody for Immunofluorescence

Recommended Neurexin 1 Antibody (supplied by: Log in to see )

Antigen
Neurexin 1 (NRXN1) Antibodies
  • Hs.22998
  • PTHSL2
  • SCZD17
  • CG7050
  • CT21808
  • Dmel\\CG7050
  • Nrx
  • Nrx1
  • dnrx
  • dnrx-1
  • nrx
  • Nrxn1b
  • NRXN1
  • Nrx-1
  • GB13455
  • GB18754
  • 1700062G21Rik
  • 9330127H16Rik
  • A230068P09Rik
  • mKIAA0578
  • neurexin 1
  • Neurexin 1
  • neurexin I
  • neurexin 1b
  • NRXN1
  • Nrx-1
  • Nrxn1
  • nrxn1
  • nrxn1b
Reactivity
Human
71
37
35
4
3
1
Host
Rabbit
49
20
5
2
2
Clonality
Polyclonal
Conjugate
Un-conjugated
3
3
3
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Western Blotting (WB)
54
40
14
11
5
5
3
1
1
1
Options
Supplier
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Available images

Catalog No. ABIN6263607
$ 390.77
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
-8.125582 ABIN5948833 ICC IF Rabbit IgG Log in to see Polyclonal 0

General

Antigen Neurexin 1 (NRXN1) Antibodies
Reactivity Human
(71), (37), (35), (4), (3), (1)
Host Rabbit
(49), (20), (5), (2), (2)
Clonality
Polyclonal
Conjugate Un-conjugated
(3), (3), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Western Blotting (WB)
(54), (40), (14), (11), (5), (5), (3), (1), (1), (1)
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Product details

Target Details Application Details Handling Images
Specificity Neurexin I Antibody detects endogenous levels of total Neurexin I
Cross-Reactivity Human
Purification The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
Immunogen A synthesized peptide derived from human Neurexin I
Isotype IgG

Target Details

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Antigen
Alternative Name Neurexin I (NRXN1 Antibody Abstract)
Background

Description: Cell surface protein involved in cell-cell-interactions, exocytosis of secretory granules and regulation of signal transmission. Function is isoform-specific. Alpha-type isoforms have a long N-terminus with six laminin G-like domains and play an important role in synaptic signal transmission. Alpha-type isoforms play a role in the regulation of calcium channel activity and Ca2+-triggered neurotransmitter release at synapses and at neuromuscular junctions. They play an important role in Ca2+-triggered exocytosis of secretory granules in pituitary gland. They may effect their functions at synapses and in endocrine cells via their interactions with proteins from the exocytotic machinery. Likewise, alpha-type isoforms play a role in regulating the activity of postsynaptic NMDA receptors, a subtype of glutamate-gated ion channels. Both alpha-type and beta-type isoforms may play a role in the formation or maintenance of synaptic junctions via their calcium-dependent interactions (via the extracellular domains) with neuroligin family members, CBLN1 or CBLN2. In vitro, triggers the de novo formation of presynaptic structures. May be involved in specification of excitatory synapses. Alpha-type isoforms were first identified as receptors for alpha-latrotoxin from spider venom (By similarity).

Gene: NRXN1

Molecular Weight 150kDa
Gene ID 9378
UniProt Q9ULB1
Pathways Synaptic Membrane, Skeletal Muscle Fiber Development

Application Details

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Application Notes WB 1:1000, IF/ICC 1:100-1:500
Restrictions For Research Use only

Handling

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Format Liquid
Concentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20 °C.Stable for 12 months from date of receipt
Expiry Date 12 months

Images

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Supplier Images
Western Blotting (WB) image for anti-Neurexin 1 (NRXN1) antibody (ABIN6263607) Western blot analysis Neurexin I using Jurkat whole cell lysates
Immunofluorescence (fixed cells) (IF/ICC) image for anti-Neurexin 1 (NRXN1) antibody (ABIN6263607) ABIN6272359 staining Hela by IF/ICC. The sample were fixed with PFA and permeabilized...