anti-Human Neurexin 1 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended Neurexin 1 Antibody

Antigen
Neurexin 1 (NRXN1) Antibodies
  • Hs.22998
  • PTHSL2
  • SCZD17
  • CG7050
  • CT21808
  • Dmel\\CG7050
  • Nrx
  • Nrx1
  • dnrx
  • dnrx-1
  • nrx
  • Nrxn1b
  • NRXN1
  • Nrx-1
  • GB13455
  • GB18754
  • 1700062G21Rik
  • 9330127H16Rik
  • A230068P09Rik
  • mKIAA0578
  • neurexin 1
  • Neurexin 1
  • neurexin I
  • neurexin 1b
  • NRXN1
  • Nrx-1
  • Nrxn1
  • nrxn1
  • nrxn1b
Epitope
AA 40-90
16
15
4
3
2
2
2
2
2
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
77
36
33
4
3
1
Host
Rabbit
55
20
5
2
2
Clonality
Polyclonal
Conjugate
Un-conjugated
4
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
53
41
13
11
5
3
3
2
1
1
1
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Available images

Catalog No. ABIN1386379
$ 317.90
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Clonality References Details
1 ABIN1409330 IHC (p) WB HRP Rabbit IgG AA 280-330 Polyclonal 0
1 ABIN1391437 IHC (p) WB Biotin Rabbit IgG AA 280-330 Polyclonal 0
1 ABIN1387438 IF (p) IHC (p) WB Rabbit IgG AA 280-330 Polyclonal 0

General

Antigen Neurexin 1 (NRXN1) Antibodies
Epitope AA 40-90
(16), (15), (4), (3), (2), (2), (2), (2), (2), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(77), (36), (33), (4), (3), (1)
Host Rabbit
(55), (20), (5), (2), (2)
Clonality
Polyclonal
Conjugate Un-conjugated
(4), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(53), (41), (13), (11), (5), (3), (3), (2), (1), (1), (1)
Supplier

Product details

Target Details Application Details Handling Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human Neurexin 1
Isotype IgG

Target Details

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Antigen
Alternative Name Neurexin 1 (NRXN1 Antibody Abstract)
Background

Neurexins comprise a family of neuronal cell surface proteins, which include neurexin I (NRXN1), neurexin II (NRXN2), neurexin III (NRXN3) and Caspr (neurexin IV). Neurexins I-III are expressed as a and b isoforms. The a isoforms are made of three cassettes, which contain two LNS (Laminin A, Neurexins, Sex hormone-binding)-domains separated by EGF domains, followed by a transmembrane region and a 55 amino acid cytoplasmic C-terminal. The a isoforms bind to neurexophilins at the second LNS site and to the excitatory neurotoxin a-latrotoxin. The b isoforms have only one LNS-domain, bind to neuroligins, and play a role in the formation and remodeling of synapes. Caspr (for Contactin-Associated Protein 1, also designated Paranodin in mouse), contains an extracellular domain similar to the other three neurexins, and binds to the surface glycoprotein Contactin. Caspr and the closely related Caspr2, a mammalian homolog of Drosophila Neurexin IV (Nrx-IV), demarcate distinct subdomains in myelinated axons. Specifically, Caspr exists at the paranodal junctions, while Caspr2 colocalizes with Shaker-like K+ channels in the juxtaparanodal region. Caspr may play a role in the communication of glial cells and neurons during development.

Subcellular location: Extracellular

Synonyms: Neurexin 1 alpha, Neurexin 1 beta, Neurexin I-alpha, Neurexin-1-alpha, NRX1A_HUMAN, NRXN1, PTHSL2.

Gene ID 9378
UniProt Q9ULB1
Pathways Synaptic Membrane, Skeletal Muscle Fiber Development

Application Details

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Application Notes WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Restrictions For Research Use only

Handling

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Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

Images

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Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Neurexin 1 (NRXN1) (AA 40-90) antibody (ABIN1386379) Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti-Neurexin 1 Po...