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MAP3K7 Proteins

(Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7))
The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2\; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008].
MAP3K7 Protein (AA 1-579) (GST tag) MAP3K7 Protein (AA 1-579) (GST tag) MAP3K7 Protein (AA 1-579) (GST tag) (ABIN1310225)

MAP3K7 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA, KAA

MAP3K7 Protein (AA 1-303) (His tag) MAP3K7 Protein (AA 1-303) (His tag) MAP3K7 Protein (AA 1-303) (His tag) (ABIN5570455)

MAP3K7 Origin: Human Host: Insect cells (Sf21) Recombinant SDS, Func Active

MAP3K7 Protein (AA 471-579) (GST tag) MAP3K7 Protein (AA 471-579) (GST tag) MAP3K7 Protein (AA 471-579) (GST tag) (ABIN1310227)

MAP3K7 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA

MAP3K7 Proteins by Grade

Find MAP3K7 Proteins with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

MAP3K7 Proteins by Origin

Find MAP3K7 Proteins for a variety of species such as anti-Human MAP3K7, anti-Mouse MAP3K7, anti-Rat MAP3K7. The species listed below are among those available. Click on a link to go to the corresponding products.

MAP3K7 Proteins by Source

Here you will find MAP3K7 Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

MAP3K7 Proteins by Protein Type

Here you can find MAP3K7 Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

MAP3K7 Proteins by Application

Find MAP3K7 Proteins validated for a specific application such as ELISA, WB, SDS, AP. Some of the available applications are listed below. Click on a link to go to the corresponding products.

MAP3K7 Proteins by Biological Activity

Find MAP3K7 Proteins with a specific Biological Activity. The Biological Activity listed below are among those available. Click on a link to go to the corresponding products.

Popular MAP3K7 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (3)
  • (1)
Cat. No. ABIN1310225
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect cells (Sf21)
Validations
  • (2)
Cat. No. ABIN5570455
Quantity 5 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1310227
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3093681
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3135494
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2733206
Quantity 20 μg
Datasheet Datasheet
Reactivity Rat
Source Yeast
Validations
Cat. No. ABIN1473820
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our MAP3K7 Proteins

Salazar, Kashiwada, Krejci, Meyer, Casale, Hallowell, Wilcox, Donoghue, Thompson: "Fibroblast growth factor receptor 3 interacts with and activates TGF?-activated kinase 1 tyrosine phosphorylation and NF?B signaling in multiple myeloma and bladder cancer." in: PLoS ONE, Vol. 9, Issue 1, pp. e86470, (2014) (PubMed).

Sorrentino, Thakur, Grimsby, Marcusson, von Bulow, Schuster, Zhang, Heldin, Landström: "The type I TGF-beta receptor engages TRAF6 to activate TAK1 in a receptor kinase-independent manner." in: Nature cell biology, Vol. 10, Issue 10, pp. 1199-207, (2008) (PubMed).

Liu, Yao, Li, Wang, Zheng, Cao: "CaMKII promotes TLR-triggered proinflammatory cytokine and type I interferon production by directly binding and activating TAK1 and IRF3 in macrophages." in: Blood, Vol. 112, Issue 13, pp. 4961-70, (2008) (PubMed).

Aliases for MAP3K7 Proteins

mitogen-activated protein kinase kinase kinase 7 (map3k7) Proteins
mitogen activated protein kinase kinase kinase 7 (Map3k7) Proteins
mitogen-activated protein kinase kinase kinase 7 (MAP3K7) Proteins
mitogen-activated protein kinase kinase kinase 7 (Map3k7) Proteins
B430101B05 Proteins
C87327 Proteins
MEKK7 Proteins
si:ch211-225h9.1 Proteins
Tak1 Proteins
TAK1 Proteins
TGF1a Proteins
zgc:110612 Proteins
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